Gene Information

Name : N559_5247 (N559_5247)
Accession : YP_008415028.1
Strain :
Genome accession: NC_022078
Putative virulence/resistance : Resistance
Product : chloramphenicol and florfenicol resistance protein (CmlA)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 149195 - 150409 bp
Length : 1215 bp
Strand : -
Note : -

DNA sequence :
ATGACCACCACACGCCCCGCGTGGGCCTATACGCTGCCGGCAGCCTTGCTGCTTATGGCTCCCTTCGACATCCTCGCCTC
GCTGGCGATGGATATTTATCTTCCAGTCGTTCCGGCGATGCCGGGCGTCCTGAACACGACTCCATCCATAATCCAACTCA
CGTTGAGCCTCTACATGGTGATGCTCGGTGTGGGCCAAGTGATCTTTGGGCCACTCTCCGATCGCGTCGGGCGACGGCCG
ATCCTGCTTGTAGGCGCAACGGCTTTCGTTGCTGCGTCTCTGGGAGCGGCTTGTTCTTCAACTGCATTAGCCTTTGTTGC
GTTTCGTCTGGTTCAGGCTGTTGGAGCATCGGCCATGCTGGTGGCCACCTTCGCGACCGTGCGCGACGTATATGCCAATC
GTCCCGAAGGTGCCGTCATCTACGGCCTTTTCAGTTCGATGCTGGCGTTCGTGCCTGCGCTCGGCCCTATAGCCGGTGCG
CTGATCGGCGAGTTTTGGGGATGGCAGGCGATCTTCATCACACTGGCTGCACTGGCTTCGCTCGCACTCTTAAACGCCAG
TTTCAGGTGGCATGAAACCCGACCGTTGGATCAGGCCAGAACGCAACGATCTGTTTTGCCGATCTTCGCGAGTCCGGCCT
TTTGGGTTTACACGGTCGGATTTAGTGCCGGCATGGGCACATTCTTCGTTTTCTTCTCGACAGCCCCCCGTGTTCTCATA
GGCCAAGCCGGCTATTCCGAGATCGGATTTAGCTTGGCCTTCGCGACTGTCGCGCTGGTCATGGTCACGACAACCCGCTT
CGCAAAGTCCTTCGTTGCCAAATGGGGTATCGCGGGATGCGTAGCGCGCGGGATGGCGTTGCTCGTTTCCGGCGCGATCC
TGTTGGGGATCGGCCAACTTTTCGGATCGCCGTCATTTTTCAGCTTCATCCTGCCGATGTGGGTTGTCGCGGTCGGCATT
GTCTTCACGGTGTCCGTTACCGCCAACGGCGCACTTGCGCAGTTCGACGACATCGCTGGATCAGCGGTTGCGTTCTACTT
CTGCATCCAAAGCCTGATAGTCAGTATCGTCGGGACATTGGCGGTGACGCTGTTAAACGGCGATACAGCGTGGCCCGTGA
TTTGTTACGCCACGGCAATGGCAGTGCTGGTGTCGTTGGGGCTGGCGCTCCTTCGATCCCGTGATGCTGCCACCGAGAAG
TCGCCAGTCGTCTAG

Protein sequence :
MTTTRPAWAYTLPAALLLMAPFDILASLAMDIYLPVVPAMPGVLNTTPSIIQLTLSLYMVMLGVGQVIFGPLSDRVGRRP
ILLVGATAFVAASLGAACSSTALAFVAFRLVQAVGASAMLVATFATVRDVYANRPEGAVIYGLFSSMLAFVPALGPIAGA
LIGEFWGWQAIFITLAALASLALLNASFRWHETRPLDQARTQRSVLPIFASPAFWVYTVGFSAGMGTFFVFFSTAPRVLI
GQAGYSEIGFSLAFATVALVMVTTTRFAKSFVAKWGIAGCVARGMALLVSGAILLGIGQLFGSPSFFSFILPMWVVAVGI
VFTVSVTANGALAQFDDIAGSAVAFYFCIQSLIVSIVGTLAVTLLNGDTAWPVICYATAMAVLVSLGLALLRSRDAATEK
SPVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 5e-173 100
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 5e-173 100
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 2e-161 93
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 2e-161 93
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 2e-161 93
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 2e-152 92
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 3e-84 50
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 6e-84 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
N559_5247 YP_008415028.1 chloramphenicol and florfenicol resistance protein (CmlA) DQ522237.1.gene4.p01 Protein 2e-84 50
N559_5247 YP_008415028.1 chloramphenicol and florfenicol resistance protein (CmlA) NC_010410.6003586.p0 Protein 2e-84 50
N559_5247 YP_008415028.1 chloramphenicol and florfenicol resistance protein (CmlA) AF294653.1.gene4.p01 Protein 7e-84 50
N559_5247 YP_008415028.1 chloramphenicol and florfenicol resistance protein (CmlA) DQ984668.gene.p01 Protein 2e-84 50
N559_5247 YP_008415028.1 chloramphenicol and florfenicol resistance protein (CmlA) AF156486.gene.p01 Protein 3e-83 49