Gene Information

Name : dhbE (RBAU_3034)
Accession : YP_008414010.1
Strain : Bacillus amyloliquefaciens UCMB-5033
Genome accession: NC_022075
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 3179321 - 3180946 bp
Length : 1626 bp
Strand : -
Note : Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; PubMedId:8921902, 9214294, 11112781, 11790741, 12354229, 12221282, 16672620, 16403027; Product type e:enzyme

DNA sequence : 
GTGCTGACTGGATTTACGCCATGGCCGGAAGAATGGGCTGACAAATACCGAAAAGACGGCTGCTGGAAGGGTGAGACGTT
CGGAGGAATGCTGAAAGAGCGCGCGGCTTTATACGGAAATCAAACTGCCGTGACGTGTAAAGATGTACATTGGACCTACA
AAGAATTAGATGAAAGGGCAGATCGTTTAGCGGCGGGGCTGCATAAGCTCGGAATTCAAAAGGAAGACCGCGTTGTCGTT
CAGCTGCCGAATATCGCTGAGTTTTTTGAAGTGATTTTCGCGCTGTTCCGGCTGGGAGCGCTGCCCGTTTTCGCGCTGCC
TTCTCATAGAAGCAGTGAGATTACGTATTTCTGCGAGTTTGCAGAGGCGAAAGCATACATCATTCCTGATATGCATTCAG
GTTTTGATTACAGGGCGCTTGCCAGACAGGTGAAAGACAAACTTCCGGATTTGGCGCATGTCATTGTGGCCGGCGAAGCT
GAAGAGTTTCAAGAACTGAGCAGCCTGCATAGAGAGCCTGTTCAGCTGGAAGAGGTAAGCCCGGCGGAAGTCGCCTTTTT
ACAGCTTTCAGGAGGCAGTACGGGGCTGTCCAAGCTGATTCCGCGAACACACGACGATTACATATACAGTTTGCGCATCA
GCGCGGAAATATGCGGCTTGGATCAACACAGCGTTTATTTGGCCGCTCTGCCGACAGCGCATAATTATCCGCTCAGCTCG
CCAGGTGTGCTGGGAACTTTATATGCCGGGGGCCGGGTTGTTCTGTCACCGACGCCGAGTCCGGATGACTGCTTCCCGTT
AATTGAAAAAGAACGTGTCACGATTACAGCGCTCGTCCCGCCGCTTGCGATGGTGTGGATGGACGCATCCGGTTCGCGAA
GTGATGATTTATCAAGCCTTCAAGTGCTGCAGGTGGGAGGCGCCAAATTCAGTGCTGAGGCGGCCCGCCGCGTGAAGAGC
GCTTTCGGATGCACCCTTCAGCAGGTTTTCGGAATGGCGGAAGGATTGGTGAATTATACGAGACTGGATGATCCTGAAGA
GATCATTGTCAATACGCAAGGCAGACCGATGTCCCCTTTTGATGAGGTAAGGGTTTTAGACGATGACGGGCGGGATGTCG
CCCCCGGTGAAGCGGGACATTTGTTTACACGCGGCCCTTACACGATTCGCGGATATTATAAAGCGCCTGAACATAATGAA
AGATCATTCACAGCCGACGGATTTTATCAGACCGGCGATATCGTCAAACTGACGGCGGACGGCTATATCATCGTCGAAGG
ACGTGCGAAAGATCAAATCAATCGGGGCGGTGAAAAAATAGCCGCTGAGGAGGTGGAAAATCACCTTCTTGCGCATCCTG
CCGTTCATGATGCGGCCATGGTTTCAATGCCGGATGATTTTCTCGGGGAGCGTTCCTGTGTGTTCGTCATCCCGAAAGGA
GAAGCGCCGAAACCGGGAGAGCTGAAAGCATTTTTGCGTGAGCGCGGACTGGCGGCATATAAAATCCCCGACCGGATTGA
ATTTATCGCTTCTTTTCCGAAAACCGGCGTCGGCAAGGTCAGTAAAAAGGATCTTCGCGAAACGATCGCCCAAAAAGTAA
AGCCGGCTGAAATCAAACAATCTTAA

Protein sequence : 
MLTGFTPWPEEWADKYRKDGCWKGETFGGMLKERAALYGNQTAVTCKDVHWTYKELDERADRLAAGLHKLGIQKEDRVVV
QLPNIAEFFEVIFALFRLGALPVFALPSHRSSEITYFCEFAEAKAYIIPDMHSGFDYRALARQVKDKLPDLAHVIVAGEA
EEFQELSSLHREPVQLEEVSPAEVAFLQLSGGSTGLSKLIPRTHDDYIYSLRISAEICGLDQHSVYLAALPTAHNYPLSS
PGVLGTLYAGGRVVLSPTPSPDDCFPLIEKERVTITALVPPLAMVWMDASGSRSDDLSSLQVLQVGGAKFSAEAARRVKS
AFGCTLQQVFGMAEGLVNYTRLDDPEEIIVNTQGRPMSPFDEVRVLDDDGRDVAPGEAGHLFTRGPYTIRGYYKAPEHNE
RSFTADGFYQTGDIVKLTADGYIIVEGRAKDQINRGGEKIAAEEVENHLLAHPAVHDAAMVSMPDDFLGERSCVFVIPKG
EAPKPGELKAFLRERGLAAYKIPDRIEFIASFPKTGVGKVSKKDLRETIAQKVKPAEIKQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 5e-120 51
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-120 51
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 4e-120 51
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-120 51
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-120 51
ybtE CAA21394.1 - Virulence HPI Protein 4e-120 51
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 3e-120 51
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-119 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-119 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_008414010.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-143 55
dhbE YP_008414010.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 1e-117 48
dhbE YP_008414010.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 7e-114 44