Gene Information

Name : gbsA (RBAU_2927)
Accession : YP_008413903.1
Strain : Bacillus amyloliquefaciens UCMB-5033
Genome accession: NC_022075
Putative virulence/resistance : Virulence
Product : glycine betaine aldehyde dehydrogenase, NAD+-dependent
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.8
Position : 3072897 - 3074369 bp
Length : 1473 bp
Strand : -
Note : Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; PubMedId:8752328, 9297465; Product type e:enzyme

DNA sequence :
ATGAGCAAAACGCTTTATATCGGCGGCGAATGGATCAGTGCAGAAAAAAAACAGACGCGCCGTATCATTAATCCATTTAA
TCAAGAAGAAATTGCAACGGTATGCGAAGGAGACCGGAACGATGCGGTGAAAGCCATCGCCGCAGCCAGAAAAGCATTTG
ATGAAGGGGAGTGGCCGGTGCTTTCCGGGCTCGAGCGCGGACAATTTGTTCTGAAAATTGCGGAATTAATCAGACGCGAT
CTGAACGAATTAGCTGAGCTGGAATCGCTCGATACAGGAAAAACGATTGAAGAAAGTAAAGCCGATATGGATGATATCGC
AAATGTATTTCAATATTATGCCGGTTTGGCGGATAAAGACGGAGGCGAGGTCATTTCATCTCCGATTCCCGATTCCGTAA
GTAAAATCGTCAGAGAGCCAATTGGCGTATGCGGACAAATTACGCCGTGGAACTATCCGCTCCTTCAGGCGAGCTGGAAA
ATCGCTCCCGCTCTTGCGGCCGGAAACACGATCGTTTTAAAGCCGAGCGAGATTACTCCGCTGACAACCATTAAAGTCTT
TCAATTAATAGAAGAAGCCGGTATTCCGAAAGGGGTCGCCAATCTTGTGCTGGGGCCGGGCGCCTCTGTCGGCGATGAGC
TGGCGAGAAACCTCGACGTCGATTTGGTCTCTTTTACGGGCGGAATTGAAACAGGCAAAAAAATCATGCAGGCGGCAAGC
GGCAATGTGAAAAAGATTGCCCTGGAGCTTGGCGGCAAAAATCCGAATATCGTATTTCAAGATGCAGATCTCGAAACAGC
TGCAGATCAAGCGCTGAACGCCGTGTTTTTCCATGCCGGCCAAGTTTGTTCGGCAGGGTCACGTCTTTTGGTGGACGAAG
CCATTCATGATGAATTTTTAGCCGAGCTGATCAAGCGCACGAAACGCATCAAATTAGGAAATGGTTTTCATGAAGATACG
GAAAGCGGTCCGCTGATTTCCGCCGAGCATCGGGCCAAAGTCGAAAAATACGTAGAAATCGGTATCGAAGAAGGGGCAAA
ACTGGAAACAGGCGGCAAACGTCCTGATGATCCCGCCCTTCAAAACGGTTTCTTCTATGAACCTACTATTTTCTCAAACT
GCAAGTCTGGTATGCGGATAGTCCAAGAGGAGATTTTCGGCCCCGTTTTAACAGTTGAGTCATTTTCATCTGAAGAAGAA
GTGATCAGACTTGCCAACGATACCATTTACGGGCTGGCCGGAGCGGTATGGTCAAAGGATATTGAAAAATGCGAACGCGT
AGCCGCCAAACTGCGGATGGGAACGGTATGGATCAATGATTTCCACCCGTATTTCGCGCAAGCGCCATGGGGCGGGTACA
AACAATCGGGCTTCGGCCGCGAACTCGGCAAAATCGGTCTGGAAGAATACACGGAAATCAAACATATTTACCGCAACACG
AAACCAGCGGCTGTGAACTGGTTTCAAGCATAA

Protein sequence :
MSKTLYIGGEWISAEKKQTRRIINPFNQEEIATVCEGDRNDAVKAIAAARKAFDEGEWPVLSGLERGQFVLKIAELIRRD
LNELAELESLDTGKTIEESKADMDDIANVFQYYAGLADKDGGEVISSPIPDSVSKIVREPIGVCGQITPWNYPLLQASWK
IAPALAAGNTIVLKPSEITPLTTIKVFQLIEEAGIPKGVANLVLGPGASVGDELARNLDVDLVSFTGGIETGKKIMQAAS
GNVKKIALELGGKNPNIVFQDADLETAADQALNAVFFHAGQVCSAGSRLLVDEAIHDEFLAELIKRTKRIKLGNGFHEDT
ESGPLISAEHRAKVEKYVEIGIEEGAKLETGGKRPDDPALQNGFFYEPTIFSNCKSGMRIVQEEIFGPVLTVESFSSEEE
VIRLANDTIYGLAGAVWSKDIEKCERVAAKLRMGTVWINDFHPYFAQAPWGGYKQSGFGRELGKIGLEEYTEIKHIYRNT
KPAAVNWFQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-75 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-77 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-77 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-77 41
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 6e-72 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
gbsA YP_008413903.1 glycine betaine aldehyde dehydrogenase, NAD+-dependent VFG0082 Protein 5e-76 42