Gene Information

Name : JCM7686_pAMI4p271 (JCM7686_pAMI4p271)
Accession : YP_008408280.1
Strain :
Genome accession: NC_022049
Putative virulence/resistance : Resistance
Product : heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.5
Position : 312535 - 314835 bp
Length : 2301 bp
Strand : -
Note : -

DNA sequence :
ATGACAGCGGCAAACCAGCGTCAGGAATGGACGGTCACCGGGATGGATTGTGCCTCGTGCACGGTGAAGATCACGCGGGC
GGTTGAGCGCATGCCCGGGGTCTCGCAGGTCCAGATCGCCTTGATGGCCGAGAAACTGAGCCTCGATCTCGACAAGGGGC
AGACCGCGCCCGAGGTGATTGAAGAGGTCGTGCGCAAGCTGGGCTTCGGCATTGCCCGCAAGGGCGAGGTGGCGCCGCGC
AAGAAGGCTTTCGTGCTGCCCGATGCCGCCCCGGCGGGCTGGCAGGGCCATGATCACGGGCACGACCATGCGCACGGGCA
TGACCACGATCACAGCCACGACCATGCCGCCACAGCAGAGGCCGCGCCGGGTCTCGCCGCCCCCAATCTCGCCACACGCC
CGGCCGAGCTTTCCTGGTATCGCAAGCCGAAGGGCCGGCTCGTGCTCTTCACGGCAGCCCTTCTGGCGCTGGCCTGGGCG
GTCGAGCTGATCGCCGGGGCAGGGGCGGGCCATTGGGCCTTCGTGCTCGCCAGCCTGATCGGCGTCGCCCCGGTCGCGCG
CCGCGCCTATGAGGCCACGCGCTTTGGCCAGCCCTTCACCATCGAGGCGCTGATGACGATTGCCGCCTTGGGCGCGCTCG
CGATCGGGGCCGCGGAAGAGGCCGCGCTCGTGGTCTTTCTCTTCGCGGTGGGCGAGCTCTTGGAAGGGGTCGCGGCGAAC
AAGGCCCGCGCCGGGATCCGCGCTCTGGCCGATCTCGTGCCGAAAACCGCGCTGGTCGAGCGCGGCGGCACGCTGCTCGA
AGTGCCCGCCGAGACGCTCGATCTGGGCGAGATCGTTCTCGTCCGCCCCGGCGAGCGCATTCCGGCGGATGGCGAGATCG
TCGAGGGGGTCAGCGGCATCGACGAAAGCCCGGTCTCGGGCGAAAGCGTGCCGCGCGTCAAGGCGCCGGGCGAGGCGGTC
TTTGCCGGTTCGGTCAATCTTGAAGCGGCGCTGCGCCTCAAGGTGACGCGCGCGGCCAGCGACAACACGATTTCGCGCAT
CATCCGTCTGGTCGAAGAGGCCGAAGAGGCGCGCGCGCCGACCGAGCGGTTCATCGACCGCTTCAGCCGCTGGTATATGC
CCTTCGTCGTGCTGCTCTCGGCGCTGGTGATCGTGGTGCCGCCGCTGGCCTTTGGCGCCGATTGGCAGGTCTGGATCTAT
CGCGGTCTGGCGCTTTTGCTGATCGGTTGCCCCTGCGCGCTGGTGATCTCGGTCCCGGCCTCGATCGCCTCGGCGCTGTC
CTCGGGGGCGCGGCGCGGGCTCTTGATGAAGGGCGGCGCGGTGATCGAGGCGGCGGCCTCCGTCACCCAGATCGCCTTTG
ACAAGACCGGCACGCTGACCGAGGGCCAGCCGCAGGTCGTCCGGCTGCTCGCGCCGGTTGCTGCGGGGGGCGGCCTCTCG
CCCGAGGTCGAGGCCGAGCTGCTCGCCACCGCCGCCGGGGTCGAGACCGGCTCGAACCACCCGCTCGCGCAGGCGATCTT
GCGCCGGGCCGAGGCGGCGGGGATCGCGGCTTTGCCCGCCAGCGGCGCGCGCGCCTTGCCCGGCAAGGGGGCGACCGCGC
TGGTTGCCGGGGCGCCCGCATATGTCGCCTCGCCGCGGGAGGCCGAGGCTGCGGGCGTGCTGACGCCCGCAGACCGCGCC
GCCGCCGCCGCAATCGAGGCCGAGGGCGCGACCGTCGTCGCGGTCTATCGCCCCGAGCGGCTGATCGGCCTGATCGGCCT
GCGCGACGAGCCGCGCGCCGATGCTGCCCCGGCGATGGCGCGGCTGCGCGAGATGGGGATCCGCGCGACCATGCTCACCG
GCGACAACCCCCGCACGGCGCAGGCGATTGCGGGCGCGCTGGGGCTCGAAGCCCGCGCCGAGATGATGCCCGAGGACAAG
CTGACCGCCATCCGCGAGATGAGCGCGGCCGGTCCGGTGATGATGATCGGCGACGGCATCAATGACGCGCCCGCGCTGAA
ACAGGCGGCGGTGGGCGTCGCGATGGGCTCGGGCACGGATGTCGCGCTCGAGACCGCCGATGCCGCGATCCTGCGCGACC
GGGTCGGCGATGCGGCCGAGCTCATTGCGCTCTCGCGTCGCACCATGGGCAATATCCGCCAGAATGTCGGCATCGCTTTG
GGGCTGAAATCGGTCTTTCTGGTGACCTCGGTTCTGGGCATGACCGGGCTCTGGCTCGCGATTCTGGCCGATACCGGCGC
GACCGTGCTGGTGACGCTGAACGCTTTGCGCCTCTTGCGCCTGCCGCGCGGCGAGGGGTGA

Protein sequence :
MTAANQRQEWTVTGMDCASCTVKITRAVERMPGVSQVQIALMAEKLSLDLDKGQTAPEVIEEVVRKLGFGIARKGEVAPR
KKAFVLPDAAPAGWQGHDHGHDHAHGHDHDHSHDHAATAEAAPGLAAPNLATRPAELSWYRKPKGRLVLFTAALLALAWA
VELIAGAGAGHWAFVLASLIGVAPVARRAYEATRFGQPFTIEALMTIAALGALAIGAAEEAALVVFLFAVGELLEGVAAN
KARAGIRALADLVPKTALVERGGTLLEVPAETLDLGEIVLVRPGERIPADGEIVEGVSGIDESPVSGESVPRVKAPGEAV
FAGSVNLEAALRLKVTRAASDNTISRIIRLVEEAEEARAPTERFIDRFSRWYMPFVVLLSALVIVVPPLAFGADWQVWIY
RGLALLLIGCPCALVISVPASIASALSSGARRGLLMKGGAVIEAAASVTQIAFDKTGTLTEGQPQVVRLLAPVAAGGGLS
PEVEAELLATAAGVETGSNHPLAQAILRRAEAAGIAALPASGARALPGKGATALVAGAPAYVASPREAEAAGVLTPADRA
AAAAIEAEGATVVAVYRPERLIGLIGLRDEPRADAAPAMARLREMGIRATMLTGDNPRTAQAIAGALGLEARAEMMPEDK
LTAIREMSAAGPVMMIGDGINDAPALKQAAVGVAMGSGTDVALETADAAILRDRVGDAAELIALSRRTMGNIRQNVGIAL
GLKSVFLVTSVLGMTGLWLAILADTGATVLVTLNALRLLRLPRGEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-86 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 5e-88 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 5e-88 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
JCM7686_pAMI4p271 YP_008408280.1 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase BAC0461 Protein 2e-98 50
JCM7686_pAMI4p271 YP_008408280.1 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase BAC0298 Protein 1e-77 42