Gene Information

Name : L144_01710 (L144_01710)
Accession : YP_008407530.1
Strain : Borrelia burgdorferi CA382
Genome accession: NC_022048
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 357016 - 358449 bp
Length : 1434 bp
Strand : +
Note : COG0469 Pyruvate kinase

DNA sequence :
ATGATTTCAAAGTTAACAAAAATTGTAGCAACAATATCTGATCTTAGATGCGAACCAGAACATATAAAAGATTTACACGA
TGCAGGGGTAAATGTTATAAGACTAAATACTGCTCATCAATCACACGAAGATACAATAAAAGTAATAGACAATGTTAGAA
AAATTTCAAATAAAATAGCTTTAATGATTGATACAAAAGGACCAGAAGTTAGAACAGCAAATATTGAAAATCCTATTATT
GTAAAAACTGGAGACAAGGTAATCATTTCAACCTCGCCTATTAATGAGCCTAATAACTTTCAAACCAATTATGATGGATT
TGTTAAAGAAGTACCCCAAGGATCTAAAGTGCTAATTGATGACGGTGAACTTGAAATGACTGTTGTTGCCAAATTGCCTG
ACAGATTAATTTGTGAAATTAAAAATGACGGCCAAATTAAAAATAAAAAATCAATCAATACCCCCGGAATTTCTCTTAAG
CTACAATCAGTAACCGAAAAAGACAAAGGATTTATTGAGCTTGCAGCAAAATATAATGTTGATTTTATTGCCCATTCGTT
TGTAAGACATTCCAAAGACGTTCAAGATGTTCAAGAAATTTTAACTGCCTCTGGAAATCCTGATGTAAAAATTATATCCA
AAATCGAAAATCAAGAGGGAATTGACAACATTGAAGAAATTGCAAAAGCTTCTTACGGAATAATGGTTGCAAGGGGAGAC
ATGGGAGTTGAAATTCCTGCAGAAGATGTACCCATTGCTCAACTTAAAATAACACAAACCTGTATAAAGCATGGAATACC
CGTGATTACAGCAACTCAAATGCTTCATACAATGATTGAAAATCCAAGACCTACTAGAGCAGAAGTGTCTGACATCGCTA
ACGCTATTTTAAACGGCACAGACGCAATTATGTTATCCGGAGAAACCGCCTACGGGAAATATCCAATTGAAGCTGTAAAA
ATGATGACAAGCATTGCTAAAAAAGTTGAAAAACACAGAAAAATGACCTTATATAAGGATGAACTTTTTTACGATAAAAG
TATCACAAGAAACTATATTATCAAATGTGCAATTGATGCCACAAAACTTATGGACATAAAAGCAATTATTGTAGATTCTC
TAAAAGGCAAAACCGCAAGAATAATGGCAACCTACAGAGCAAGTGTTCCATTATTCATTACAACAAATAGCGAAAGACTA
GCAAGAGAATTAGCATTATCTTACGGGGTTTATTCTAATCTTGTAGACAATAATTTCAAAAGAACTACCGAATTTGTAGT
AACTTCTCTTAAAATGTTAAAAGAACAAGGTGTTGTTAATGACAAAGATACTGTAATAATTATTTCTGGAAATCCAAATA
GAAATATTGAAAAAGGAACAGAATTTATGGAAATAAACACAGTAGAAGATGCAATCAAAGGACGAAATATATAA

Protein sequence :
MISKLTKIVATISDLRCEPEHIKDLHDAGVNVIRLNTAHQSHEDTIKVIDNVRKISNKIALMIDTKGPEVRTANIENPII
VKTGDKVIISTSPINEPNNFQTNYDGFVKEVPQGSKVLIDDGELEMTVVAKLPDRLICEIKNDGQIKNKKSINTPGISLK
LQSVTEKDKGFIELAAKYNVDFIAHSFVRHSKDVQDVQEILTASGNPDVKIISKIENQEGIDNIEEIAKASYGIMVARGD
MGVEIPAEDVPIAQLKITQTCIKHGIPVITATQMLHTMIENPRPTRAEVSDIANAILNGTDAIMLSGETAYGKYPIEAVK
MMTSIAKKVEKHRKMTLYKDELFYDKSITRNYIIKCAIDATKLMDIKAIIVDSLKGKTARIMATYRASVPLFITTNSERL
ARELALSYGVYSNLVDNNFKRTTEFVVTSLKMLKEQGVVNDKDTVIIISGNPNRNIEKGTEFMEINTVEDAIKGRNI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-68 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-68 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-68 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
L144_01710 YP_008407530.1 pyruvate kinase VFG0479 Protein 8e-69 41