Gene Information

Name : metB (cgp_2687)
Accession : YP_008402306.1
Strain : Corynebacterium glutamicum MB001
Genome accession: NC_022040
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 2358523 - 2359683 bp
Length : 1161 bp
Strand : -
Note : Cystathionine beta-lyases/cystathionine gamma- synthases

DNA sequence :
TTGTCTTTTGACCCAAACACCCAGGGTTTCTCCACTGCATCGATTCACGCTGGGTATGAGCCAGACGACTACTACGGTTC
GATTAACACCCCAATCTATGCCTCCACCACCTTCGCGCAGAACGCTCCAAACGAACTGCGCAAAGGCTACGAGTACACCC
GTGTGGGCAACCCCACCATCGTGGCATTAGAGCAGACCGTCGCAGCACTCGAAGGCGCAAAGTATGGCCGCGCATTCTCC
TCCGGCATGGCTGCAACCGACATCCTGTTCCGCATCATCCTCAAGCCGGGCGATCACATCGTCCTCGGCAACGATGCTTA
CGGCGGAACCTACCGCCTGATCGACACCGTATTCACCGCATGGGGCGTCGAATACACCGTTGTTGATACCTCCGTCGTGG
AAGAGGTCAAGGCAGCGATCAAGGACAACACCAAGCTGATCTGGGTGGAAACCCCAACCAACCCAGCACTTGGCATCACC
GACATCGAAGCAGTAGCAAAGCTCACCGAAGGCACCAACGCCAAGCTGGTTGTTGACAACACCTTCGCATCCCCATACCT
GCAGCAGCCACTAAAACTCGGCGCACACGCAGTCCTGCACTCCACCACCAAGTACATCGGAGGACACTCCGACGTTGTTG
GCGGCCTTGTGGTTACCAACGACCAGGAAATGGACGAAGAACTGCTGTTCATGCAGGGCGGCATCGGACCGATCCCATCA
GTTTTCGATGCATACCTGACCGCCCGTGGCCTCAAGACCCTTGCAGTGCGCATGGATCGCCACTGCGACAACGCAGAAAA
GATCGCGGAATTCCTGGACTCCCGCCCAGAGGTCTCCACCGTGCTCTACCCAGGTCTGAAGAACCACCCAGGCCACGAAG
TCGCAGCGAAGCAGATGAAGCGCTTCGGCGGCATGATCTCCGTCCGTTTCGCAGGCGGCGAAGAAGCAGCTAAGAAGTTC
TGTACCTCCACCAAACTGATCTGTCTGGCCGAGTCCCTCGGTGGCGTGGAATCCCTCCTGGAGCACCCAGCAACCATGAC
CCACCAGTCAGCTGCCGGCTCTCAGCTCGAGGTTCCCCGCGACCTCGTGCGCATCTCCATTGGTATTGAAGACATTGAAG
ACCTGCTCGCAGATGTCGAGCAGGCCCTCAATAACCTTTAG

Protein sequence :
MSFDPNTQGFSTASIHAGYEPDDYYGSINTPIYASTTFAQNAPNELRKGYEYTRVGNPTIVALEQTVAALEGAKYGRAFS
SGMAATDILFRIILKPGDHIVLGNDAYGGTYRLIDTVFTAWGVEYTVVDTSVVEEVKAAIKDNTKLIWVETPTNPALGIT
DIEAVAKLTEGTNAKLVVDNTFASPYLQQPLKLGAHAVLHSTTKYIGGHSDVVGGLVVTNDQEMDEELLFMQGGIGPIPS
VFDAYLTARGLKTLAVRMDRHCDNAEKIAEFLDSRPEVSTVLYPGLKNHPGHEVAAKQMKRFGGMISVRFAGGEEAAKKF
CTSTKLICLAESLGGVESLLEHPATMTHQSAAGSQLEVPRDLVRISIGIEDIEDLLADVEQALNNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-71 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-72 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-59 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_008402306.1 cystathionine gamma-synthase BAC0207 Protein 4e-66 42