Gene Information

Name : topB (BB2000_1529)
Accession : YP_008398080.1
Strain : Proteus mirabilis BB2000
Genome accession: NC_022000
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1670389 - 1672356 bp
Length : 1968 bp
Strand : -
Note : matching_protein_id: YP_002151227.1; matching_locus_tag: PMI1496

DNA sequence :
ATGAGATTATTTATTGCAGAAAAACCCAGCCTTGCTCGAGCTATTGCTGATGTATTACCAAAACCGCATAAACGTGGTGA
TGGTTTTATTGTTTGTGGTGATAACCAGTATGTGACGTGGTGTGTTGGTCATTTACTTGAGCAGGCTGAGCCGGATGCAT
ATGATCCGCGCTATGCGCGTTGGTCGTTAGATGATTTGCCCATTATTCCGAATAAATGGCAACTCAAACCGCGCGCTGAT
GTGAAAAAACAGCTAGATACGATCAACACATTACTAAAACAAGCCGATGAAGTGATCCACGCAGGAGACCCCGATCGCGA
AGGGCAACTGTTGGTAGATGAAGTACTTAATTACCTTAATATTAGTGATGCTCAAAGAAAACAGGCACGCCGCTGCCTGA
TTAACGATTTAAACCCCGCCGCGGTATCTCGAGCAATTGATAAGCTCCGCTACAATCATGAATTTATTCCATTATGTGTT
TCTGCCTTAGCAAGAGCGAGGGCGGATTGGCTATATGGCATTAACATGACACGCGCTTACACGTTATTAGGACAGCGCAA
TGGTTACCAAGGCGTACTTTCTGTTGGGCGAGTACAAACCCCGGTGCTGGGTTTAGTCGTACGCCGTGATGAAGAAATTG
AAAACTTTGTACCGAAAGATTTTTTTGAAGTCAAAGCGCATATCGTTACTCCTGCAGATGAGCGATTTACCGCTATTTGG
CAGCCGAGTGAACACTGCGAGCCTTGGCAAGATGAAGAAGGGCGTTTATTACATCGCAAATTAGCAGAGCATGTTGTTGA
TAGAATAGCTGGCAAGCCTGCTAATGTTACCGATTATCAAGATAAACAAGAGTCTGAAATAGCACCTTTGCCTTTTTCAT
TATCTGCTTTACAAATTGAAGCGGCGAAACGCTTTGGTTTAAGCGCTCAACAAGTGTTAGACACATGTCAACGCTTATAT
GAAACGCATAAACTTATTACTTATCCACGCTCCGATAGTCGCTATCTGCCTGATGAACACTTTGCTGGGCGTCATGCGGT
GATGAATGCCATTAGTGTGCATGATAATAGTCTTTTACCACAAGAAACATTAGATATTGATAAAAAGAACCGTTGCTGGG
ATGACAAGAAAGTAGATGCGCACCATGCCATTATTCCTACTGCGAAAACAGGTAATATTTCATTAAGTGAAAATGAAAAG
AATATTTACTATTTGATTGCCCGACAATATCTAATGCAATTTATGCCAGATGCGGTGTACCGCAAATGTGTGATTGAACT
CGATATTGAGAATGGAAAGTTTATTGCTAAGGCACGATTTTTAGCACAAGCTGGCTGGCGTACCTTATTAGGTAGTAAAG
AGCAAGATGCGGAAAATGATGGTAGCGCCTTACCTATTGTGGCTAAAGGTGATGAGTTACTTTGTGAAAAAGGCGAAATT
GTTGCCAAGCAGACCCAACCACCAAGACCTTTTACAGATGCTACGCTACTTTCGGCTATGACCGGTATTGCACGTTTTGT
GCAAGACAAAGAGCTAAAGAAAATCCTAAGAGCGACGGATGGGCTAGGTACTGAAGCGACTAGGGCTGGTATTATTGAAT
TACTGTTTAAACGCGGCTTTCTGCAAAAGAAAGGGCGAGCTATCAACTCGACACCAGCAGGAAGAGCATTAATTCATGTT
TTGCCAGATATGGCGACATTACCCGATATGACCGCTCATTGGGAATCAATATTAACGCAAATTAGTGAGAAGCAATTTAA
GTATCAAGATTTTATGATGCCATTAAGTAACACACTATTTGAATTAATTACTCAAGCTAAACGTCGTCCTAATATTCAAG
CGTTTAGAAACCTGCCTGCGCCTGCGCAGAATAAAAAACGTAAAGGTGCGACGAAAAAAAGTGCACAAGGGAAAAGTCGT
TCAGCGCAGTCTCAATCTACGAATCGCAATATAAAGAGTGATGCTTAG

Protein sequence :
MRLFIAEKPSLARAIADVLPKPHKRGDGFIVCGDNQYVTWCVGHLLEQAEPDAYDPRYARWSLDDLPIIPNKWQLKPRAD
VKKQLDTINTLLKQADEVIHAGDPDREGQLLVDEVLNYLNISDAQRKQARRCLINDLNPAAVSRAIDKLRYNHEFIPLCV
SALARARADWLYGINMTRAYTLLGQRNGYQGVLSVGRVQTPVLGLVVRRDEEIENFVPKDFFEVKAHIVTPADERFTAIW
QPSEHCEPWQDEEGRLLHRKLAEHVVDRIAGKPANVTDYQDKQESEIAPLPFSLSALQIEAAKRFGLSAQQVLDTCQRLY
ETHKLITYPRSDSRYLPDEHFAGRHAVMNAISVHDNSLLPQETLDIDKKNRCWDDKKVDAHHAIIPTAKTGNISLSENEK
NIYYLIARQYLMQFMPDAVYRKCVIELDIENGKFIAKARFLAQAGWRTLLGSKEQDAENDGSALPIVAKGDELLCEKGEI
VAKQTQPPRPFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFKRGFLQKKGRAINSTPAGRALIHV
LPDMATLPDMTAHWESILTQISEKQFKYQDFMMPLSNTLFELITQAKRRPNIQAFRNLPAPAQNKKRKGATKKSAQGKSR
SAQSQSTNRNIKSDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 1e-109 42
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 1e-109 42
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 9e-110 42
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-111 41