Gene Information

Name : vanHB (EFAU085_00734)
Accession : YP_008394258.1
Strain : Enterococcus faecium AUS0085
Genome accession: NC_021994
Putative virulence/resistance : Resistance
Product : VanH protein, D-specific alpha-keto acid dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.1.1.-
Position : 773954 - 774925 bp
Length : 972 bp
Strand : +
Note : van locus

DNA sequence :
ATGAGAAAAAGTGTGGGCATTACTGTTTTTGGATGCGAACAGGATGAGGCAAATGCTTTCCGCGCTTTATCGCCGGATTT
TCATATTATCCCTACGCTGATTAGCGATGCGATATCGGCAGACAACGCAAAATTGGCCGCTGGCAATCAATGCGTTAGCG
TAGGCCATAAGTCCGAGGTTTCCGAGGCGACAATTCTTGCGCTGAGAAAGGTCGGGGTAAAATACATTTCTACCCGCAGC
ATCGGCTGCGATCACATTGATACGACTGCCGCCGAGAGAATGGGAATCTCGGTTGGCACGGTTGCGTATTCGCCGGACAG
CGTTGCGGATTATGCTTTGATGCTGATGCTGATGGCCATACGGGGTGCAAAACCCACCATGCACGCCGTGGCGCAACAAG
ATTTCAGATTGGATCGTATCCGGGGGAAAGAACTGGGGGATATGACTGTGGGAGTTATTGGAACCGGCCATATCGGGCAA
GCGGTCGTCAAAAGGCTGCGGGGATTTGGATGCCATGTGCTGGCCTATGATAACAGCCGAAAAATGGATGCAGATTATGT
CCAGCTTGATGAGCTTCTAAAAAACAGCGATATTGTTACGCTCCATGTGCCGCTTTGTGCGGATACCCGCCATCTGATCG
GTCAGAAGCAAATTGGAGAGATGAAGCAAGGCGCATTTTTAATCAACACCGCGCGCGGAGCGCTTGTCGATACCGGGGCG
CTGGTGGAGGCGTTGGAAAGCGGAAAGCTGGGTGGTGCGGCACTGGATGTGTTGGAGGGCGAGGATCAGTTTGTTTATAC
CGATTGCTCGCAGAAAGTGCTTGACCATCCCTTTTTGTCGCAGCTTTTAAGGATGCCGAATGTGATCATCACACCCCATA
CGGCGTACTACACTGAGCGTGTGCTGCAGGATACTACAGAAAAAACAATCAGGAATTGTCTCAATTTTGAAAGGAGTTTA
CAGCATGAATAG

Protein sequence :
MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAKLAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRS
IGCDHIDTTAAERMGISVGTVAYSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQIGEMKQGAFLINTARGALVDTGA
LVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSL
QHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 2e-152 100
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 8e-146 95

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase AF310956.2.orf4.gene Protein 1e-152 99
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase U35369.1.gene5.p01 Protein 1e-145 95
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase AF155139.2.orf4.gene Protein 4e-106 68
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase NC_014475.1.orf2.gen Protein 5e-111 67
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase NC_005054.2598279.p0 Protein 5e-111 67
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase AF130997.1.orf3.gene Protein 4e-94 63
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase FJ349556.1.orf3.gene Protein 1e-101 62