Gene Information

Name : aadE (EFAU085_p3016)
Accession : YP_008390868.1
Strain :
Genome accession: NC_021988
Putative virulence/resistance : Resistance
Product : Streptomycin adenyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.-
Position : 11040 - 11948 bp
Length : 909 bp
Strand : -
Note : -

DNA sequence : 
ATGAGATCAGAAAAAGAAATGATGGATTTAGTACTTTCTTTAGCAGAACAGGATGAACGTATTCGAATTGTGACCCTTGA
GGGGTCACGCGCAAATATTAATATACCTAAAGATGAATTTCAGGATTATGATATTACATATTTTGTAAGTGATATAGAAC
CGTTTATATCTAATGATGACTGGCTTAATCAATTTGGGAATATAATAATGATGCAAAAGCCGGAGGATATGGAATTATTC
CCACCTGAAGAAAAGGGATTTTCCTATCTTATGCTATTTGATGATTACAATAAAATTGATCTTACCTTATTGCCCTTGGA
AGAGTTAGATAATTACCTAAAGGGCGATAAATTAATAAAGGTTCTAATTGATAAAGATTGTAGAATTAAAAGGGACATAG
TTCCGACTGATATAGATTATCATGTAAGAAAGCCAAGCGCAAGGGAGTATGATGATTGCTGCAATGAATTTTGGAATGTA
ACACCTTATGTTATTAAAGGATTGTGCCGTAAGGAAATTTTATTTGCTATTGATCATTTTAATCAGATTGTTCGCCATGA
GCTGCTGAGAATGATATCATGGAAGGTCGGCATCGAAACAGGCTTTAAATTAAGTGTAGGCAAGAACTATAAGTTTATTG
AAAGGTATATATCCGAGGATTTGTGGGAGAAACTTTTGTCCACCTACCGGATGGATTCCTATGAAAACATATGGGAAGCA
TTATTTCTATGCCATCAATTGTTCAGGGCGGTATCCGGTGAGGTGGCGGAAAGGCTTCATTATGCCTATCCGGAGTATGA
TAGGAATATAACAAAATATACCAGGGACATGTATAAAAAATACACTGGTAAAACCGGCTGCCTGGATAGCACATATGCCG
CTGATATAGAAGAGAGGCGGGAACAGTGA

Protein sequence : 
MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELF
PPEEKGFSYLMLFDDYNKIDLTLLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLWEKLLSTYRMDSYENIWEA
LFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKYTGKTGCLDSTYAADIEERREQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadE AFJ97257.1 streptomycin aminoglycoside 6-adenyltransferase Not tested Not named Protein 5e-104 97
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 1e-133 94
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 3e-120 90
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 3e-120 90
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 7e-88 64

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadE YP_008390868.1 Streptomycin adenyltransferase NC_006663.1.orf0.gen Protein 1e-129 99
aadE YP_008390868.1 Streptomycin adenyltransferase AJ489618.1.orf2.gene Protein 1e-99 88
aadE YP_008390868.1 Streptomycin adenyltransferase FN594949.1.gene25.p0 Protein 3e-88 64