Gene Information

Name : B446_31975 (B446_31975)
Accession : YP_008390010.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Virulence
Product : DNA binding ATP-dependent peptidase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 7402862 - 7405342 bp
Length : 2481 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAGCACACCCGGCTTCGGATTCGGCCGCAGCCCCTTCGAGGAGTTCGACGAGCTGATGTCCCGGTTCTTCGGGCCGGG
CGGGCAGACGGCGCCGGCCGCCCGCAGGCCCCAGCGCGTCGACATCGGCAGTCTGCTCTCCGAGCGGGCCATGGAGCTGG
TGGCGGAGGCCAGGGACATCGCGGGCGCCGAGGGCAGCGAGGAGCTGGACGCCCGCCACCTGCTGGCCGCGGCGACCCGC
AACGAGTCCACGCGGCGCCTGCTCACCGAGTCCGGCACCGACCCGGACCGGCTCCGCGAGCAGCTCGGCACCACGGGGAA
CGGCGGCGAGCGGACCGAACCCACGACGCTCACCCCGTCGGCCAAGCGCGCCCTCCTCGACGCCTACCGTGTCTCCCGGG
CCGAGGACGCCTCCTACATCGGCCCCGGCCATCTGCTGCGGGCCCTCGCCGCCAACCCGGAGTCGGCCGCCGGGCAGGCG
CTCGGCGACGGCGGCTGGGAGCCCACCCGGCTGCCCACCGAGGGCCAGGCCGAGCGGAAGAAGCCCAGCAGCACCCCGAC
CGTCGACGAGTACGGCCGCGATCTCACCCAGGACGCCCGCGACGGCCGCCTCGACCCGGTGATCGGGCGCGACGACGAGG
TCGAGCAGACCATCGAGGTGCTCTCCCGGCGCAGCAAGAACAACCCCGTCCTGATCGGCGACCCCGGAGTCGGCAAGACC
GCCGTGGTCGAGGGCATCGCCCAGCGCATCGTCGCCGGCGACGTGCCCAGGACGCTCGCCGGCAAGCGGCTCGTCTCCCT
GGACCTGGCCGGCATGGTGGCCGGCACCAAGTACCGGGGCGAGTTCGAGGAACGGCTGAAGAAGCTGCTGGACGAGGTCG
GTGAGCACGGCGACGAACTCATCCTGTTCCTCGACGAGTTGCACACCGTGGTCGGGGCGGGAGGCGGCGGTGAGGGTGCG
ATGGACGCGGGCAACATGCTCAAGCCCGCCCTCGCCCGCGGGGAGCTGCACCTGATCGGCGCGACGACGGTGGACGAGTA
CCGCAGGCACATCGAGAAGGACGCCGCCCTGGAGCGCCGCTTCGCACCCATCCTGGTCGGCGAGCCCGGCGTGGACGACA
CCATCGAGATCCTGCGCGGCCTGCGCGACCGCTACGAGGCCCACCACCAGGTCCGCATCACCGACGAGGCGGTGGTGGCC
GCGGCCGAGCTGTCCGACCGGTACATCACCTCCCGCTTCCTGCCCGACAAGGCGATCGACCTGATGGACCAGGCCGCCGC
CCGGGTCCGGCTGCGGGCCGGGACCCCGCTGGAGGACACCCGGGAGATCGAGGACCGCGTCGCCGCCCTGAACCGGGAGA
AGGACCAGGCCGTCGCCGACGAGGAGTACGAGCGCGCCAAGGAGCTCAGGGACCGGATCAAGGAGGCGGAGGCCGAACTG
GCCGCGGCGGGCCGGACCGACGAGCACGCCCCGAAGGTCACCGCCGAGGACATCGCCCAGGTCGTCTCCCGCACCACCGG
CATCCCGGTCGCCCAGCTCACCGAGGAGGAGCGGGAACGGCTGATGAAGCTGGAGGAACACCTGCACGGGCGGGTGGTCG
GCCAGGACGAGGCGATCACCGCCGTCGCCCGGGCCGTGCGCCGTGCCCGGGCCGGCATGAGCGACCCCAACCGTCCCGTC
GGCAGCTTCCTGTTCCTCGGCCCGACCGGCGTCGGCAAGACCGAACTGGCCCGCGCGCTCGCCGCCGCCCTCTTCGGCGA
CGAGAGCCGCATGATCCGCCTGGACATGAGCGAGTTCCAGGAGCGGCACACCGTCTCCCGGCTGGTCGGCGCCCCGCCCG
GATACGTCGGCCACGAGGAGGCCGGCCAGCTCACCGAGGCCGTGCGCAGGCAGCCGTACGCCGTCCTGCTGCTGGACGAG
GTGGAGAAGGCCCACCCCGACGTCTTCAACACCCTGCTGCAGCTCCTGGACGACGGCCGCCTCACCGACTCCCAGGGCCG
CACCGTCGACTTCAAGAACACCGTCGTCATCATGACGTCGAACATCGGCGCCGACCGCATCCTGGCCGCGGGCACGGAGG
ACTACGGCAAGATCCGCGAGGCGGTCATGCCGGTCCTCCAGCAGCACTTCCGGCCGGAGTTCCTCAACCGCATCGACGAG
ATCATCGTCTTCCGCGGCCTGGACCGCACCGAACTGCGCCAGGTCGTGGACCTGATGCTGGAGCACACCCGGCGCCGCCT
GCACGCCCAGGACGTCTCCCTGGAGGTCACCGACGCGGCCGCCGACCTGCTCGCGAACCTCGGCCACCAGCCCGACTTCG
GCGCACGCCCGCTGCGCCGCACCATCCAGCGCGAGGTGGACGACCGCCTCGCCGACCTGCTCCTCTCCGGCCGGCTCGGC
GCGGGCGACCGGGCGGTGGTGGACGCGCCGGACGGCTCGGTGGAGATCCGGACGGACAAGCCGGCCGCCGTGGAGGGCTG
A

Protein sequence :
MSTPGFGFGRSPFEEFDELMSRFFGPGGQTAPAARRPQRVDIGSLLSERAMELVAEARDIAGAEGSEELDARHLLAAATR
NESTRRLLTESGTDPDRLREQLGTTGNGGERTEPTTLTPSAKRALLDAYRVSRAEDASYIGPGHLLRALAANPESAAGQA
LGDGGWEPTRLPTEGQAERKKPSSTPTVDEYGRDLTQDARDGRLDPVIGRDDEVEQTIEVLSRRSKNNPVLIGDPGVGKT
AVVEGIAQRIVAGDVPRTLAGKRLVSLDLAGMVAGTKYRGEFEERLKKLLDEVGEHGDELILFLDELHTVVGAGGGGEGA
MDAGNMLKPALARGELHLIGATTVDEYRRHIEKDAALERRFAPILVGEPGVDDTIEILRGLRDRYEAHHQVRITDEAVVA
AAELSDRYITSRFLPDKAIDLMDQAAARVRLRAGTPLEDTREIEDRVAALNREKDQAVADEEYERAKELRDRIKEAEAEL
AAAGRTDEHAPKVTAEDIAQVVSRTTGIPVAQLTEEERERLMKLEEHLHGRVVGQDEAITAVARAVRRARAGMSDPNRPV
GSFLFLGPTGVGKTELARALAAALFGDESRMIRLDMSEFQERHTVSRLVGAPPGYVGHEEAGQLTEAVRRQPYAVLLLDE
VEKAHPDVFNTLLQLLDDGRLTDSQGRTVDFKNTVVIMTSNIGADRILAAGTEDYGKIREAVMPVLQQHFRPEFLNRIDE
IIVFRGLDRTELRQVVDLMLEHTRRRLHAQDVSLEVTDAAADLLANLGHQPDFGARPLRRTIQREVDDRLADLLLSGRLG
AGDRAVVDAPDGSVEIRTDKPAAVEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-162 55
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-87 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
B446_31975 YP_008390010.1 DNA binding ATP-dependent peptidase VFG0080 Protein 3e-148 51
B446_31975 YP_008390010.1 DNA binding ATP-dependent peptidase VFG0079 Protein 4e-171 49
B446_31975 YP_008390010.1 DNA binding ATP-dependent peptidase VFG2084 Protein 1e-89 41