Gene Information

Name : lysS (B446_31890)
Accession : YP_008389993.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Unknown
Product : lysyl-tRNA ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 7381387 - 7384665 bp
Length : 3279 bp
Strand : +
Note : COG2898 Uncharacterized conserved protein

DNA sequence :
ATGACTGCCACCGCCGGGCCGGACGCACGCGGGTCGGCCGCGGGCCGGACACTCCCGCCCGCCGGCGGCCGCCTCGGCTG
GGTGCCCGAGGCCTTCGGGACCCTGTTCGCCTTCCTCGGCCTGCTCTGCGCGCTGCTCGCGTTCATCGCCCCCCTGCGCA
CCGTGCTCCGCCCGGTCGTGCGCGCCCTCGACCTGCTCCTGGTGCCGATCAGCGCCAACCTGGCGTACGCGGTCTTCCTG
TTCCTGCTGGCCGGCGCCACCGCCGCCCGCAAGAAGGTCGCCTGGTGGCTGGTCGTGGTCTACCTGGGCCTGCTGGTCGT
CTTCGACGTCCTCGGCCTGGCCCTGGGCCAGTACGCCGTCTCGCTGCCCTCCTTCGTGCTCTGCGGCCTGCTGCTGCTCC
TGCTGGTGCTCGCCCGCGCGGAGTTCTACGCGGCCTCCCGCCGCGGTGCCGTGTGGCGCGCCCTGGGGGTGCTGGTGGCC
GGGCTCGTCGTCGCCATCGTCGTCGGCTGGGGGCTGGTCTCGCTGTTCCCGGGCACCCTGCCGGAGGGCCAGCACCTGGC
GTGGGCGGCGGACCGGGTGTGCGGCGGGCTGGTCTCCAACAGCTCCTTCGACGGCCGGCCGCCGCGCAAGGTCACCTTCC
TGCTCGGCCTGTTCGGCGCGCTCGCGCTGCTGAACGCGGCCGCCGCGCTCTTCCGCTCCCAGCGCCTGGAAGCGGCCCTG
CACGGCGACGAGGAGGCACGTATCCGCGCCCTCCTCGGGGCCTACGGCGCACAGGACTCGCTCGGCTACTTCGCCACCCG
GCGGGACAAGGCCGTCGTCTTCTCCTCCAGCGGCAAGGCCGCCGTCACCTACCGCGTCGAGGCCGGCGTGTGCCTGGCCA
GCGGCGACCCCGTGGGCGACCCCGAGGCGTGGCCGCACGCGATCGCCGCGTGGCTGGACGTGGCCCGCCGGCACGCCTGG
GCGCCCGCGGTGATGGGCGCCTCGGAGTCCGGGGCCCGCGCCTTCGCCCGCGCCGGGCTCGGCGCCCTCCAGCTCGGCGA
CGAGGCGATCGTGCACGTGTCCGGGTTCGACCTGAACGGCCGGGACATGCGTGTCACCCGGCAGGCCGTGCACCGCGTCC
GCCGCACCGGGGCCACCTCGCGCATCCGCCGCCACGCCACCCTCACCGACCGCGAGATGGAGGAGATCGTCGACAAGGCC
GACGCCTGGCGCGACACCGAGACCGAGCGCGGCTTCTCCATGGCCCTGGACCGGCTCGGCGACCCCAGCGACGGCGACTG
CCTCCTCGTGGAGGCCCTGAGCGAGGACGGCAGGCTGCTCGCCCTGCTCTCCTTCGTGCCCTGGGGCCGCGGCGGCGTCT
CCCTGGACCTGATGCGCCGTGACCGCAGCGCCCCCAACGGGGTGATGGAGTTCATGGTCGCCGAACTGTGCGCGGCCGCC
CCGAAGCTGGGGGTGCGCAGGATCTCGCTGAACTTCGCCGTCTTCCGGTCGGTGTTCGAGGAGGGCGCCCGCATCGGCGC
GGGCCCGGTGCTGAGGCTGTGGCGCCGGCTGCTGCTGTTCTTCTCCCGCTGGTGGCAGCTGGAGGCCCTCTACCGCTCCA
ACGCCAAGTACCGCCCGGAGTGGTACCCGCGCTTCATCTGCTACGGCGAGACCGCCTCCCTCGCCCGCATCGGCCTCGCC
TCCGCCATCGCCGAGGGGTTCGTCTCCGTGCCTTCGCTGCGCAAACTCTGGGGAAAGGGGCACCCGAAGACAGGGCAGCG
GCCCGCCACCACCGAGGGCCTGCCGCCCCTGGCGGCGCTCGGCCTCGACGGAGGGGACGAGGCCGGGACCGCCGTCCCGG
ACGCGGGCCTGTCCGACCAGGTCCGCGTCCGGCTCCGCAAGCTCGACCGGCTGCGCGCCACCGGCACCGACCCGTACCCG
GTCGGCGGTCCCACCCCGACCCACGCCCTCGCCGACGTCCCGCACGGCGGGGACGTCACCGTGGCAGGCCGGGTCATGCT
GGTCCGCGACTTCGGCGGCATCGTCTTCGCCGTGCTGCGGGACTGGTCCGGGGACCGTCAACTCGCCCTCATCCGCGACC
GGTCCGGCGCCGCCCTCGACCGTTTCCGGGACACGGCCGACATCGGCGACCACATCACCGCCACCGGCCGCGCGGGGGTG
AGCGACAAGGGCGAGCCCACCGTCTTCGTCACCTCGTGGCACCTGGCCGGCAAGTGCCTGCACCCGCTGCCCGACAAGCG
CCGCGGCCTCGCCGACCCCGAGGCCCGGGTCCGCCGCCGCTACCTCGACCTGGTCACCAGCCCCGCCGCCCGCCAGGTGG
TCCGCACCCGCTCCACCGTCGTCCAGGCCCTGCGCCAGGGCCTGCTGGACCGCGGCTACGTCGAGGTCGAGACGCCGATG
CTGCAGCAGATCCACGGCGGCGCCAACGCACGCCCCTTCACCACCCACATCAACGCCTACGACCTCGACCTCTACCTGCG
CATCGCGCCCGAGCTGTACCTCAAACGGCTGTGCGTGGGCGGCCTGGAGCGGGTCTTCGAGATGGGCCGCACCTTCCGCA
ACGAGGGCGTCTCCTACAAGCACAACCCCGAGTTCACGATGCTGGAGGCCTACCAGGCGCACGCCGACTACGACGTGATG
CGCGACCTGGCCCGTGAGCTGATCCAGGGCGCGGCGACCGCCGCCTTCGGCTCCGCGGTCGCCCGCAAGGACGGCCGGGA
GTACGACATCTCGGGGGACTGGCCCGTGAAGACGGTCCACGGGGCGCTCTCCGAGGCCCTGGGCGAGGAGATCGGCCCCG
GCACCGAACTGCTCAGGCTGCACCGGCTGTGCGACCGCACGGGCGTGCCGTACACCCCCGACGACACCCCGGGCGACGTG
GTCCTGGAGATGTACGAGCGGCTGGTCGAGGAGCGCACCCGGCTGCCCACGTTCTACAAGGACTTCCCCACCGAGGTCTC
CCCGCTCACCCGGCAGCACCGCGCCGACCCGCGCCTCGCCGAGCGCTGGGACCTCGTCGCCTTCGGCACCGAACTCGGCA
CCGCCTACTCCGAACTGACCGACCCCGTCGAACAGCGCCGCCGGCTCACCGAGCAGTCCCTGCTGGCCGCGGGCGGCGAC
CCCGAGGCCATGGAGCTCGACGAGGACTTCCTCGACGCCCTGGAGTACGCGATGCCGCCGACCGGCGGCCTCGGCATCGG
CGTCGACCGGCTGGTCATGTTCCTCACCGGCCTCACCATCCGCGAGACCCTGCCCTTCCCGCTGGTGCGCCGCCGCTAG

Protein sequence :
MTATAGPDARGSAAGRTLPPAGGRLGWVPEAFGTLFAFLGLLCALLAFIAPLRTVLRPVVRALDLLLVPISANLAYAVFL
FLLAGATAARKKVAWWLVVVYLGLLVVFDVLGLALGQYAVSLPSFVLCGLLLLLLVLARAEFYAASRRGAVWRALGVLVA
GLVVAIVVGWGLVSLFPGTLPEGQHLAWAADRVCGGLVSNSSFDGRPPRKVTFLLGLFGALALLNAAAALFRSQRLEAAL
HGDEEARIRALLGAYGAQDSLGYFATRRDKAVVFSSSGKAAVTYRVEAGVCLASGDPVGDPEAWPHAIAAWLDVARRHAW
APAVMGASESGARAFARAGLGALQLGDEAIVHVSGFDLNGRDMRVTRQAVHRVRRTGATSRIRRHATLTDREMEEIVDKA
DAWRDTETERGFSMALDRLGDPSDGDCLLVEALSEDGRLLALLSFVPWGRGGVSLDLMRRDRSAPNGVMEFMVAELCAAA
PKLGVRRISLNFAVFRSVFEEGARIGAGPVLRLWRRLLLFFSRWWQLEALYRSNAKYRPEWYPRFICYGETASLARIGLA
SAIAEGFVSVPSLRKLWGKGHPKTGQRPATTEGLPPLAALGLDGGDEAGTAVPDAGLSDQVRVRLRKLDRLRATGTDPYP
VGGPTPTHALADVPHGGDVTVAGRVMLVRDFGGIVFAVLRDWSGDRQLALIRDRSGAALDRFRDTADIGDHITATGRAGV
SDKGEPTVFVTSWHLAGKCLHPLPDKRRGLADPEARVRRRYLDLVTSPAARQVVRTRSTVVQALRQGLLDRGYVEVETPM
LQQIHGGANARPFTTHINAYDLDLYLRIAPELYLKRLCVGGLERVFEMGRTFRNEGVSYKHNPEFTMLEAYQAHADYDVM
RDLARELIQGAATAAFGSAVARKDGREYDISGDWPVKTVHGALSEALGEEIGPGTELLRLHRLCDRTGVPYTPDDTPGDV
VLEMYERLVEERTRLPTFYKDFPTEVSPLTRQHRADPRLAERWDLVAFGTELGTAYSELTDPVEQRRRLTEQSLLAAGGD
PEAMELDEDFLDALEYAMPPTGGLGIGVDRLVMFLTGLTIRETLPFPLVRRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 6e-154 46
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-153 46
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 6e-154 46
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 6e-154 46