Gene Information

Name : ureC2 (B446_25930)
Accession : YP_008388805.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 5968347 - 5970071 bp
Length : 1725 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAGCCGCTCCAAGGGCCGGGAGATCAGCCGCGCCACCCAGGTCGACCCGCACGCGTACGCCGCCACGCACGGCCCCCG
GGCCGGCGACCGCGTCCGGCTCGGCGACTCCGGCCTCGTCGTCCGGGTCGAGTCGGACGCCCAGAAGTACGGCGACGAGT
TCCTCGCCGGCTTCGGCAAGACCGCCCGCGACGGACTGCACCTGAAGGCCGCCGCCGTCCGCGACACCTGCGACGTCGTG
ATCAGCAACGTCCTCGTGATCGACGCCGCGCAGGGCATCCGCAAGGTCTCGATCGGCATCCGCGAGGGCCGGATCTGCGC
CGTCGGACGCGCGGGGAACCCGGACACCCTCGACGGGGTCGACGTCGTCGTGGGCACGGGCACGTCCATCGTCTCCGGCG
AGGGCCTGATCGCCACCGCCGGCGCCGTCGACACCCATGTCCACCTGCTGTCGCCGCGGATCATGGAGGCCTCGCTGGCC
TCCGGCGTCACCACGATCATCGGGCAGGAGTTCGGCCCGGTGTGGGGGGTCGGCGTCAACTCGCCGTGGGCGCTGCGGCA
CGCCTTCAACGCCTTCGACGCCTGGCCGGTCAACATCGGCTTCCTGGGCCGCGGCTCGTCCTCGCACGACGCTCCCCTGG
TCGAGGCGCTGGCCGAGGGCGGGGCCTCGGGGTTCAAGGTGCACGAGGACATGGGCGCCCACACCCGTGCCCTGGACACC
GCCCTGCGGGTCGCGGAGGAGCACGACGTCCAGGTCGCCCTGCACAGCGACGGCCTCAACGAGTGCCTCTCGGTCGAGGA
CACCCTCCGCGTCCTGGAGGGCCGCACGATCCACGCCTTCCACATCGAGGGCTGCGGCGGCGGGCACGTGCCCAACGTGC
TGAAGATGGCCGGGGTCCCGAACGTCATCGGCTCCTCCACCAACCCGACCCTGCCCTTCGGCCGGGACGCGGTCGCCGAG
CACTACGGCATGATCGTCTCCGTCCACGACCTGAAGACCGACCTGCCCGGCGACGCGGCCATGGCCCGCGACCGCATCCG
GGCCGGCACGATGGGCGCCGAGGACGTGCTGCACGACCTGGGCGCGATCGGCATCACCTCCTCCGACGCCCAGGGCATGG
GCCGCGCGGGCGAGACGGTCCGGCGCACCTTCGCCATGGCGGGGAAGATGAAGGCCGAACTGGGCCCGATGGAGGGCGAC
GGCGAGGGCGACGACAACGCCCGCGTCCTGCGCTACATGGCCAAGCTGACCATCAACCCGGCCATCGCCCACGGTCTCGC
GCACGAGGTCGGCTCGATCGAGGCCGGCAAGCTCGCCGACATCGTGCTGTGGCGCCCCGAGTACTTCGGCGCCAAGCCGC
AGCTCGTCCTCAAGTCCGGCTTCCCGGCGTACGGCGTGGTCGGCGACCCCAACGCGGCCACCGACACCTGCGAACCGCTC
GTGCTCGGACCGCAGTTCGGCGCGCACGGCAGCACGCCCGCCGACATCTCGGTCGCCTTCGTCGCCCAGGCCGCCGTGGA
CCAGGGCAACGACACGATGCCCACCCGCCGCCGCCGGGTCGCGGTGCGCGGCACCCGGGGGATCGGCCCGGCCGACCTGC
GCCTGAACGCCCGCGTCGGAGCGGTCGACGTCGACCAGCGCACCGGCCTGGTCACCCTCGACGGCGACCCGCTGCGCTCC
GAGCCCGCCGAGTCCGTCTCCCTCAACCGCCTCTACTTCCTCTAA

Protein sequence :
MSRSKGREISRATQVDPHAYAATHGPRAGDRVRLGDSGLVVRVESDAQKYGDEFLAGFGKTARDGLHLKAAAVRDTCDVV
ISNVLVIDAAQGIRKVSIGIREGRICAVGRAGNPDTLDGVDVVVGTGTSIVSGEGLIATAGAVDTHVHLLSPRIMEASLA
SGVTTIIGQEFGPVWGVGVNSPWALRHAFNAFDAWPVNIGFLGRGSSSHDAPLVEALAEGGASGFKVHEDMGAHTRALDT
ALRVAEEHDVQVALHSDGLNECLSVEDTLRVLEGRTIHAFHIEGCGGGHVPNVLKMAGVPNVIGSSTNPTLPFGRDAVAE
HYGMIVSVHDLKTDLPGDAAMARDRIRAGTMGAEDVLHDLGAIGITSSDAQGMGRAGETVRRTFAMAGKMKAELGPMEGD
GEGDDNARVLRYMAKLTINPAIAHGLAHEVGSIEAGKLADIVLWRPEYFGAKPQLVLKSGFPAYGVVGDPNAATDTCEPL
VLGPQFGAHGSTPADISVAFVAQAAVDQGNDTMPTRRRRVAVRGTRGIGPADLRLNARVGAVDVDQRTGLVTLDGDPLRS
EPAESVSLNRLYFL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-99 46
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-99 46
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-95 46
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-95 45
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-95 45
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-95 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC2 YP_008388805.1 urease subunit alpha VFG0270 Protein 3e-96 43