Gene Information

Name : B446_25410 (B446_25410)
Accession : YP_008388704.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5843244 - 5844671 bp
Length : 1428 bp
Strand : -
Note : COG0469 Pyruvate kinase

DNA sequence :
ATGCGCCGTTCGAAAATCGTCTGTACTCTCGGCCCCGCGGTCGACTCCCACGAAAAGCTCGTCGCCATGATCGAGGCGGG
CATGAACGTGGCCCGTTTCAACTTCAGCCACGGCTCCCACGCCGAGCACCAGGCGCGGTACGACCGCGTCCGGGCCGCCG
CCAAGGAGACCGGTCGGGCCATCGGTGTCCTCGCCGACCTCCAGGGCCCGAAGATCCGCCTGGAGACCTTCGCCGAAGGT
CCCGTCGAGCTGGAGCGCGGTGACGAGTTCGTCATCACGACCGAGGACGTACCGGGCGACAAGCACATCTGCGGTACGAC
GTACAAGGGGCTGCCGGGCGACGTCTCGCGCGGCGACCAGATCCTGATCAACGACGGCAACGTCGAGCTCAAGGTCGTGG
ACGTCGAGGGCCCGCGGGTGAAGACGATCGTGATCGAGGGCGGTGTCGTCTCCGACCACAAGGGGATCAACCTGCCCGGC
GCGGCCGTCAACGTGCCCGCGCTGTCCGACAAGGACGTCGAGGACCTGCGCTTCGCCCTCCGCATGGGCTGCGACATGGT
CGCGCTGTCCTTCGTCCGGGACGCCAAGGACGTCGCCGACGTCCACCGCGTGATGGACGAGGAGGGTCGCCGGGTCCCGG
TCATCGCCAAGGTGGAGAAGCCGCAGGCGGTGGAGAACATGGAGGACGTCGTCGCGGCGTTCGACGCCGTGATGGTCGCC
CGCGGTGACCTCGCCGTCGAGTACCCGCTCGAGAAGGTCCCCATGGTGCAGAAGCGCCTGATCGAGCTGTGCCGGCGCAA
CGCCAAGCCGGTGATCGTGGCGACCCAGATGATGGAGTCGATGATCACCAACTCCCGTCCGACCCGCGCCGAGGCCTCCG
ACGTGGCCAACGCGATCCTGGACGGCGCGGACGCGGTCATGCTGTCCGCCGAGTCCTCGGTCGGCGCCTACCCGGTCGAG
ACGGTCAAGACGATGTCGAAGATCGTCACCGCGGCCGAGCAGGAACTGCTCTCCAAGGGCCTGCAGCCCCTGGTGCCCGG
CAAGAAGCCGCGCACGCAGGGCGGTTCGGTGGCCCGCGCGGCCTGCGAGATCGCCGACTTCCTCGGCGGCCGCGGCCTGA
TCGCCTTCACCCAGTCCGGTGACACCGCCCGCCGGCTGTCCCGCTACCGGGCGGCCCAGCCGATCCTCGCCTTCACCACC
GACGAGGGCACCCGCAACCAGCTCACCCTGAGCTGGGGCGTGGAGCCGCACGTCGTGCCGTTCGTCAACAGCACCGACGA
GATGGTCGACATGGTGGACCAGGAGCTGGCCAACCTGGGCCGCTTCAACCCCGGCGACACGGTGATCATCACCGCCGGCT
CGCCCCCCGGTGTCCCCGGCACGACCAACATGGTCCGGGTCCACCACGTGGGCGGCCAGGGCGCCTGA

Protein sequence :
MRRSKIVCTLGPAVDSHEKLVAMIEAGMNVARFNFSHGSHAEHQARYDRVRAAAKETGRAIGVLADLQGPKIRLETFAEG
PVELERGDEFVITTEDVPGDKHICGTTYKGLPGDVSRGDQILINDGNVELKVVDVEGPRVKTIVIEGGVVSDHKGINLPG
AAVNVPALSDKDVEDLRFALRMGCDMVALSFVRDAKDVADVHRVMDEEGRRVPVIAKVEKPQAVENMEDVVAAFDAVMVA
RGDLAVEYPLEKVPMVQKRLIELCRRNAKPVIVATQMMESMITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPVE
TVKTMSKIVTAAEQELLSKGLQPLVPGKKPRTQGGSVARAACEIADFLGGRGLIAFTQSGDTARRLSRYRAAQPILAFTT
DEGTRNQLTLSWGVEPHVVPFVNSTDEMVDMVDQELANLGRFNPGDTVIITAGSPPGVPGTTNMVRVHHVGGQGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-74 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-75 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-75 42
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-63 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-74 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
B446_25410 YP_008388704.1 pyruvate kinase VFG0479 Protein 3e-75 42