Gene Information

Name : guaA (B446_22455)
Accession : YP_008388114.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 5159509 - 5161089 bp
Length : 1581 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
GTGTCATCAGCGACTTCCACTGCCGCCAGTCCCGACACCGTCCTGGTCGTGGACTTCGGTGCGCAGTACGCCCAGCTCAT
CGCCCGTCGTGTCCGCGAGGCGCGGGTCTACAGCGAGATCGTGCCGAGCACCATGCCGGTCCAGGAGATGCTCGCCAGGA
ACCCCGCGGCGATCATCCTCTCCGGCGGCCCCTCGTCCGTGTACGAGGAGGGTGCCCCCCGCCTCGACGGCGCGCTGTTC
GAGGCGGGTGTCCCCGTCTTCGGCATGTGCTACGGCTTCCAGCTGATGGCACAGGTGCTCGGCGGCACCGTCGACAACAC
CGGCGCCCGCGAGTACGGCCGCACCGACCTGCACGTCTCCCGGTCCGGTTCCACCCTCTTCGAGGGCACCCCCGACGAGC
AGCACGTGTGGATGTCGCACGGCGACGCCTGCTCCGCCGCCCCCGAGGGCTTCTCGGTCACCGCGTCCACGGACGTCGTC
CCGGTCGCCGCCTTCGAGAACGACGAGAAGCGGCTCTACGGCGTCCAGTACCACCCCGAGGTCATGCACTCCACGCACGG
CCAGCAGGTGCTGGAGCACTTCCTGTACCGCGGCGCGGGCCTGAAGCCCGACTGGACCACCGGCAACGTCATCGACGAGC
AGGTGGCCGCCATCCGCGAGCAGGTCGGCGACAAGCGGGCGATCTGCGGTCTGTCCGGCGGCGTGGACTCCGCGGTCGCC
GCCGCCCTCGTGGCGCGCGCCATCGGTGACCAGCTCACCTGCGTGTACGTCGACCACGGCCTGATGCGCAAGGGCGAGAC
CGAGCAGGTCGAGAAGGACTTCGTGGCCGCGACCGGCGTCAAGCTGGTCGTCGTGGACGCCGAGGAGCGGTTCCTCGCCG
CGCTCAAGGGCGTCAGCGACCCCGAGGAGAAGCGCAAGATCATCGGCCGTGAGTTCATCCGCGTCTTCGAGCAGGCGCAG
GCCGAGATCATCGCCGACCAGGGCCCGGCCGTCGAGTTCCTGGTCCAGGGCACCCTGTACCCGGACGTGGTCGAGTCCGG
CGGCGGCACCGGCACCGCCAACATCAAGTCGCACCACAACGTCGGCGGCCTGCCCGAGGACCTGGAGTTCCAGCTCATCG
AGCCGCTGCGCAAGCTGTTCAAGGACGAGGTCCGCATGGTCGGCCAGGAGCTCGGCCTGCCGGAGGAGATCGTCCAGCGC
CAGCCCTTCCCGGGCCCCGGCCTCGGCATCCGCATCGTCGGCGAGGTCACCAAGGAGCGCCTGGACCTGCTGCGCGACGC
GGACGCCATCGCCCGCGAGGAGCTGACCGCGGCCGGCCTCGACCGGGACATCTGGCAGTGCCCGGTGGTGCTGCTCGCGG
ACGTCCGCTCCGTCGGCGTCCAGGGCGACGGCCGCACCTACGGCCACCCGATCGTGCTGCGCCCGGTCTCCTCCGAGGAC
GCCATGACGGCCGACTGGTCCCGCCTGCCGTACGACGTCCTCGCCCGCATCTCGACCCGGATCACCAACGAGGTCCGGGA
CGTCAACCGGGTCGTCCTCGACGTGACCTCGAAGCCGCCGGGCACCATCGAGTGGGAGTAG

Protein sequence :
MSSATSTAASPDTVLVVDFGAQYAQLIARRVREARVYSEIVPSTMPVQEMLARNPAAIILSGGPSSVYEEGAPRLDGALF
EAGVPVFGMCYGFQLMAQVLGGTVDNTGAREYGRTDLHVSRSGSTLFEGTPDEQHVWMSHGDACSAAPEGFSVTASTDVV
PVAAFENDEKRLYGVQYHPEVMHSTHGQQVLEHFLYRGAGLKPDWTTGNVIDEQVAAIREQVGDKRAICGLSGGVDSAVA
AALVARAIGDQLTCVYVDHGLMRKGETEQVEKDFVAATGVKLVVVDAEERFLAALKGVSDPEEKRKIIGREFIRVFEQAQ
AEIIADQGPAVEFLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPEDLEFQLIEPLRKLFKDEVRMVGQELGLPEEIVQR
QPFPGPGLGIRIVGEVTKERLDLLRDADAIAREELTAAGLDRDIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSED
AMTADWSRLPYDVLARISTRITNEVRDVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-176 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-132 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-132 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-132 52