Gene Information

Name : B446_21250 (B446_21250)
Accession : YP_008387873.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Virulence
Product : response regulator mprA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4906546 - 4907217 bp
Length : 672 bp
Strand : -
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
ATGCACTACCTGGTCGTCGACGACGAGGCGCGCCTCACGGACCTCGTCGTCCGCTACCTCAGCGAGTCGGGCCACACCGC
TGAGGGCCGCTACGACGGGCCCTCGGGACTCGCCGCCGCCCGCGATCCCCGGCTGGACGGGGTGGTCCTGGACGTGATGC
TGCCGGGCCTCGACGGCGTCGAGGTGTGCCGCACGCTGCGCGGTGAGGGCATCGACGTGCCCGTGGTCCTGCTCACCGCG
CGCGGCGCGGTCGGCGAACGCGTCGCGGGTCTGGACGCGGGCGCCGACGACTACATGGTCAAGCCGTTCGCCATGGAGGA
GCTGCTGGCCCGGCTGCGCGCGATATCCCGGCGCCGCCCGGAGTGCTCCGGCCGCCTCCAGGTGGGCGACCTCGTGCTGG
ACGCCGAGCGACGGCGCGCCTGGCGGGCGGACACGGAGCTGGACCTGTCCCGGCGGGAGTTCGCCGTGCTGCGGGTGCTG
ATGGAGAACGCCGGCCGGGTGGTGACCCGGCTCCAGTTGCTCGACGAGGTCTGGGACGGTGAGACCGACCTGCGCAGCAA
CGCCATCGACGTGCACGTCTCCAAGGTCCGCGCGAAGGTCGACCGCGCCTTCGGACGCACCTCGATCACCACCCTGCGCG
GGGTCGGCTACCGCCTGGAGACGGCCCCGTGA

Protein sequence : 
MHYLVVDDEARLTDLVVRYLSESGHTAEGRYDGPSGLAAARDPRLDGVVLDVMLPGLDGVEVCRTLRGEGIDVPVVLLTA
RGAVGERVAGLDAGADDYMVKPFAMEELLARLRAISRRRPECSGRLQVGDLVLDAERRRAWRADTELDLSRREFAVLRVL
MENAGRVVTRLQLLDEVWDGETDLRSNAIDVHVSKVRAKVDRAFGRTSITTLRGVGYRLETAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 4e-32 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
B446_21250 YP_008387873.1 response regulator mprA BAC0083 Protein 1e-29 43
B446_21250 YP_008387873.1 response regulator mprA HE999704.1.gene1528. Protein 1e-30 43
B446_21250 YP_008387873.1 response regulator mprA BAC0125 Protein 5e-32 41
B446_21250 YP_008387873.1 response regulator mprA BAC0197 Protein 5e-26 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
B446_21250 YP_008387873.1 response regulator mprA VFG1390 Protein 7e-33 45
B446_21250 YP_008387873.1 response regulator mprA VFG1389 Protein 3e-28 43
B446_21250 YP_008387873.1 response regulator mprA VFG0596 Protein 1e-32 41
B446_21250 YP_008387873.1 response regulator mprA VFG1386 Protein 4e-30 41