Gene Information

Name : B446_20840 (B446_20840)
Accession : YP_008387791.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Virulence
Product : Clp family ATP-binding protease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4814055 - 4816580 bp
Length : 2526 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGTCTCATCCACGAGGGCGAAGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGCA
TTTCGCTTGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGTCAGGGCCAGCAGGCCCCGTCCGGCCACATCCCCTTC
ACCCCCCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTTCAGCTGGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTGGTCAAGCTGGGCGCAGACCTCAACCGGG
TGCGGCAGCAGGTGATCCAGCTGCTCTCCGGTTACCAGGGCAAGGAGACCGCCACCGCCGGCGGCCCGGCCGAGGGCACG
CCCTCGACCTCTCTGGTCCTGGACCAGTTCGGCCGGAACCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGCACCAAGAACAACCCGGTGCTGATCGGTGAGC
CCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTCGCCCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTCGACCTCGGCGCGCTGGTGGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTGCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTCGGTGCGGGTGCCG
CCGAGGGCGCCATCGACGCCGCCTCCATCCTGAAGCCGATGCTGGCCCGTGGTGAGCTCCAGACCATCGGTGCGACCACG
CTGGACGAGTACCGCAAGCACCTGGAGAAGGACGCGGCCCTCGAGCGCCGCTTCCAGCCCATCCAGGTCGCGGAGCCGTC
CCTGCCGCACACGATCGAGATCCTCAAGGGTCTGCGCGACCGGTACGAGGCGCACCACCGCGTGTCCATCACGGACGAGG
CGCTGGTCCAGGCCGCCACGCTGGCCGACCGCTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGTTCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCCGCCGT
CCGCCGGGACAAGGAGTCCGCGATCGACTCGCAGGACTTCGAGAAGGCCGCCTCCCTGCGCGACAAGGAGAAGCAGCTCC
TGGCCGCCAAGGCCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGCGAGCTGATC
GCCGAGGTCCTCGCCACGGCCACGGGCATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCAGCCGCCTGCTCCGCATGGA
GGACGAGCTCCACAAGCGGGTCATCGGCCAGGTCGACGCCGTCAAGGCGCTGTCGAAGGCGATCCGCCGTACGCGTGCCG
GTCTGAAGGACCCGAAGCGTCCCGGTGGTTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACCGAGCTGTCCAAG
GCGCTCGCCGAGTTCCTCTTCGGCGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
CTCGCGTCTCTTCGGTTCGCCCCCCGGCTACGTGGGCTACGAGGAGGGCGGCCAGCTGACCGAGAAGGTCCGCCGCAAGC
CGTTCTCCGTCGTCCTCTTCGACGAGGTCGAGAAGGCGCACCCGGACATCTTCAACTCGCTGCTGCAGATCCTGGAGGAC
GGTCGTCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGCACCCG
GGACATCTCCAAGGGCTTCAACCTGGGCTTCGCGGCCTCGGGTGACACGAAGACCAACTACGAGCGCATGAAGAACAAGG
TCCAGGACGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGCGTCGACGACGTGGTCGTCTTCCCGCAGCTGACG
CAGGAGGACATCCTGCGGATCGTCGACCTGATGATCAGCAAGGTGGACGAGCGCCTGAAGGACCGGGACATGGGCATCGA
GCTCTCCCAGTCCGCCAAGGAGCTGCTGTCCAAGAAGGGTTACGACCCGGTGCTGGGCGCGCGTCCGCTGCGCCGCACGA
TCCAGCGTGAGGTCGAGGACACGCTCTCGGAGAAGATCCTCTTCGGCGAGCTGCGTCCCGGTCACATCGTGGTCGTGGAC
ACCGAGGGCGAGGGCGACGCCGCCACCTTCACCTTCCGGGGTGAGGAGAAGTCGGCGCTGCCGGACGTCCCGCCGATCGA
GCAGGCGGCCGGCGGTGCCGGGCCGAACCTGAGCAAGGACGCGTAA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKETATAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAAVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQVDAVKALSKAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
ALAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAASGDTKTNYERMKNKVQDELKQHFRPEFLNRVDDVVVFPQLT
QEDILRIVDLMISKVDERLKDRDMGIELSQSAKELLSKKGYDPVLGARPLRRTIQREVEDTLSEKILFGELRPGHIVVVD
TEGEGDAATFTFRGEEKSALPDVPPIEQAAGGAGPNLSKDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
B446_20840 YP_008387791.1 Clp family ATP-binding protease VFG0079 Protein 0.0 62
B446_20840 YP_008387791.1 Clp family ATP-binding protease VFG0080 Protein 5e-152 52