Gene Information

Name : B446_18910 (B446_18910)
Accession : YP_008387407.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4353554 - 4355338 bp
Length : 1785 bp
Strand : -
Note : COG0422 Thiamine biosynthesis protein ThiC

DNA sequence :
ATGACCAACAAGGACGCACGCACGCCTGCCTCCGTTCAGGACGACATGTCCCAGGAGGCCGGGAAGTCCATCGGCTGGCA
CAAGGCGTACGTCGAGGGCACCCGCTCCGACCTGCGCGTGCCGGTCCGTCAGGTGCACCTCACCAACGGGCAGTCGGTCA
CCTTGTACGACACGTCGGGCCCGTACACCGATCCACTCGTCGACACCGATGTCCGCCGGGGACTGGCACCCCTGCGGGAG
AACTGGATCATCGCTCGCGGTGACACCGAGGAGTACGCGGGCCGTCCCGTCCGGCCCGAGGACGACGGCATCAAGCACAC
CGCGCCCCGCGGCGGACTGCGCAACCTCGACGCGGTCTTCCCCGGCCGCCCCCGCCAGCCCCGCCGGGGCCGTGCGGGTG
AGGCGGTCACCCAGCTCGCCTACGCGCGCCGGGGTGAGATCACGCCGGAGATGGAGTTCGTCGCGCTCCGGGAGAACGTC
GATCCCGACGTGGTCCGCGAGGAGATCGCTGCGGGACGCGCGGTGCTGCCGGCCAACGTCAACCACCCGGAGATCGAGCC
GATGATCATCGGCAAGCGGTTCCTGGTGAAGGTCAACGCCAACATCGGCAACTCGGCGGTCACCTCCTCCATCGAGGAGG
AGGTCGAGAAGATGACCTGGGCGACCCGCTGGGGCGCCGACACGGTCATGGACCTGTCCACCGGCCGCAACATCCACACC
ACCCGCGAGTGGGTGCTGCGCAACTCCCCCGTCCCCATCGGCACGGTGCCGCTCTACCAGGCGCTGGAGAAGGTCGACGG
CAGGGCCGAGGAACTGACCTGGGAGATCTACAAGGACACCGTCATCGAGCAGGCCGAGCAGGGCGTGGACTACATGACCG
TCCACGCGGGCGTCCGGCTGCCGTACGTGCCGCTCACCGCCCGCCGCAAGACCGGCATCGTCTCGCGCGGCGGCTCCATC
ATGGCCGCGTGGTGCCTGGCGCACCACAAGGAATCGTTCCTGTACGAGAACTTCGAGGAGCTCTGCGAGATCCTCGCCGC
CTACGACGTCACGTACTCGCTGGGCGACGGCCTGCGGCCGGGCTCGATCGCCGACGCCAACGACGAGGCGCAGTTCGCGG
AGTTGCGCACGCTCGGGGAACTCAACCGGATCGCCAGGCGTTTTGACGTACAGACGATGATCGAGGGCCCGGGCCACGTC
CCGATGCACAAGATCAAGGAGAACATCGACCTTCAGCAGGAGATCTGCGATGAAGCTCCGTTCTATACGCTCGGCCCGCT
GACCACCGACGTCGCGCCGGCGTACGACCACATCACCTCCGGCATCGGCGCCGCGATGATCGCCTGGTGGGGCACCGCGA
TGCTCTGCTACGTGACGCCCAAGGAGCACCTGGGTCTGCCCAACCGCGACGACGTCAAGACGGGCGTGATCACCTACAAG
ATCGCCGCGCACGCGGCCGACCTGGCCAAGGGCCACCCTGGCGCCCAGGAGTGGGACGACGCGCTCTCCGACGCCCGCTT
CGAGTTCCGCTGGGAGGACCAGTTCAATCTCGCGCTGGACCCGGACACGGCGCGGGAGTTCCACGACGAGACACTGCCGG
CCGAGCCCGCCAAGACGGCCCACTTCTGCTCGATGTGCGGGCCGAAGTTCTGCAGCATGAAGATCTCGCAGGACATCCGC
CGTGAACACGGGGGCAGTCAGGCCGAGATCGAGGAGGGCATGGCGCAGAAGTCGAAGGAGTTCGCCGCCGCGGGCAATCG
GGTGTACCTGCCGCTGGCGGAGTGA

Protein sequence :
MTNKDARTPASVQDDMSQEAGKSIGWHKAYVEGTRSDLRVPVRQVHLTNGQSVTLYDTSGPYTDPLVDTDVRRGLAPLRE
NWIIARGDTEEYAGRPVRPEDDGIKHTAPRGGLRNLDAVFPGRPRQPRRGRAGEAVTQLAYARRGEITPEMEFVALRENV
DPDVVREEIAAGRAVLPANVNHPEIEPMIIGKRFLVKVNANIGNSAVTSSIEEEVEKMTWATRWGADTVMDLSTGRNIHT
TREWVLRNSPVPIGTVPLYQALEKVDGRAEELTWEIYKDTVIEQAEQGVDYMTVHAGVRLPYVPLTARRKTGIVSRGGSI
MAAWCLAHHKESFLYENFEELCEILAAYDVTYSLGDGLRPGSIADANDEAQFAELRTLGELNRIARRFDVQTMIEGPGHV
PMHKIKENIDLQQEICDEAPFYTLGPLTTDVAPAYDHITSGIGAAMIAWWGTAMLCYVTPKEHLGLPNRDDVKTGVITYK
IAAHAADLAKGHPGAQEWDDALSDARFEFRWEDQFNLALDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMKISQDIR
REHGGSQAEIEEGMAQKSKEFAAAGNRVYLPLAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 63
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 63
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-170 58