Gene Information

Name : B446_10500 (B446_10500)
Accession : YP_008385733.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2446382 - 2447818 bp
Length : 1437 bp
Strand : -
Note : COG0469 Pyruvate kinase

DNA sequence :
ATGCGCCGAGCAAAGATCGTTTGTACTCTGGGCCCCGCCACCGACACGTACGACCAGATCAAGGCACTGGTCGAGGCCGG
AATGGACGTCGCCCGGTTCAACCTCAGCCACGGCACGCACGCCGAGCACGAGGAGCGTTACCGGCGGGTGCGGAAGGCGG
CCGACGAAACCGGCCGCAGCGTCGGAATCCTCGCCGACCTTCAAGGTCCGAAGATCCGGCTGGGCCGCTTCGCCGAGGGC
CCCGTATTCCTTGAACGCGGCGACCCCTTCACCATCACCGTGGAGGAGGGCGTCGAGGGCGACCGTCACCGCTGCGGCAC
CACCTACGCGGGCCTCGCCGGTGACGTCACCCCCGGTGAGCGGGTCCTCGTGGACGACGGCAAGGTCTGCCTGGAGGTCA
CCGCGGTCGACGGGCCGCGCGTCCGCACCCGGGTGGTCGAGGGCGGGGTGATCTCCGATCACAAGGGCCTCAACCTCCCC
GGCGTGGCCGTCTCCGTCCCCGCCCTCTCCAAGAAGGACGAGGACGACCTGCGCTGGGCGCTGCGCACCGGCTTCGACGT
CGTCGCCCTCTCCTTCGTGCGCAGCGGCAGGGACGCCGACGACGTGCACCGCATCATGGCGGAGGAGGGCCGCCGCCTCC
CGGTCATCGCCAAGGTGGAGAAGCCGCAGGCCGTCGAGAACATCGACGACATCGTGGCCGCCTTCGACGGGATCATGGTC
GCCCGCGGCGACCTCGGCGTGGAGATGCCGCTGGAGCAGGTCCCGATCGTGCAGAAACGCGCCGTCAAGCTGGCCCGGCG
CAACGCCAAGCCGGTCATCGTGGCCACCCAGATGCTCGACTCGATGATCGACAACGCCCGCCCGACCCGCGCCGAGGCCT
CGGACGTCGCCAACGCGGTCATCGACGGCACGGACGCGGTGATGCTCTCCGGCGAGACCAGCGTCGGCAAGCACCCGATC
GAGACCGTGCGGACCATGGCGAAGATCATCGAGGCCGCCGAGGAGGACATCCTCGCCAAGGGCCTGGCGCCGCTGACCGA
GCGGAACAAGCCGCGCACCCAGGGCGGCGCGGTCGCCCGGGCCGCCGCCGAGATGGGCGACTTCCTCGGCGCCCGGTTCC
TGGTCGCCTTCACCCAGTCGGGAGACACCGCCCGCCGGCTGTCCCGCTACCGCTCGCCGATCCCGCTGCTGGCCTTCACC
CCCGAGCAGGCCACCCGCTCCCAGCTCAGCCTGACCTGGGGCGCCGAGACCTTCCTCGGTCCGCCGGTCGGCTCCACGGA
CGCCATGGTCGACCAGGTGGACGAACTGCTGCTGAAGTACGGCCGCTGCCGGAAGGGTGACGTCGTGGTCATCACGGCGG
GCTCCCCGCCCGGTGTCTCCGGCGCGACCAACATGGTCCGGGTGCACCACATCGGCGAGGACGACAGCCCCCGGTGA

Protein sequence :
MRRAKIVCTLGPATDTYDQIKALVEAGMDVARFNLSHGTHAEHEERYRRVRKAADETGRSVGILADLQGPKIRLGRFAEG
PVFLERGDPFTITVEEGVEGDRHRCGTTYAGLAGDVTPGERVLVDDGKVCLEVTAVDGPRVRTRVVEGGVISDHKGLNLP
GVAVSVPALSKKDEDDLRWALRTGFDVVALSFVRSGRDADDVHRIMAEEGRRLPVIAKVEKPQAVENIDDIVAAFDGIMV
ARGDLGVEMPLEQVPIVQKRAVKLARRNAKPVIVATQMLDSMIDNARPTRAEASDVANAVIDGTDAVMLSGETSVGKHPI
ETVRTMAKIIEAAEEDILAKGLAPLTERNKPRTQGGAVARAAAEMGDFLGARFLVAFTQSGDTARRLSRYRSPIPLLAFT
PEQATRSQLSLTWGAETFLGPPVGSTDAMVDQVDELLLKYGRCRKGDVVVITAGSPPGVSGATNMVRVHHIGEDDSPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-79 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-78 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-78 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-79 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
B446_10500 YP_008385733.1 pyruvate kinase VFG0479 Protein 3e-79 42