Gene Information

Name : ureC1 (B446_06450)
Accession : YP_008384925.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 1546599 - 1548320 bp
Length : 1722 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGCATGAGATCTCCCGCGCGGCCTACGCCGACCTGTTCGGCCCCACCACGGGCGACCGCATCCGGCTCGCCGACACCGA
CCTGCTGATCGAGATCGAGGAGGACCTCGCCGGCGGTCCCGGACGCGCCGGCGACGAGGCGGTCTTCGGCGGCGGCAAGG
TCGTCCGCGAGTCCATGGGCCAGTCCCGCGCCACCCGCGCCGAGGGCACCCCCGACACCGTCGTCACCGGAGTGGTCGTC
GTCGACCACTGGGGCGTCGTCAAGGCCGACGTGGGCATCCGCGACGGCCGGATCACCGGCATCGGCAAGGCCGGCAACCC
CGACACCATGGACGGCGTCCACCCCGACCTGGTCATCGGCCCCGAGACCGAGATCATCGCGGGCAACGGACGCATCCTCA
CCGCCGGTGCCATCGACGCGCACGTCCACTTCATCTGCCCCCAGGTCGCCGACGAGGCGCTGGCCTCCGGCATCACCACC
CTGGTCGGCGGCGGCACCGGGCCCGCCGAGGGCTCCAAGGCGACCACCGTGACACCCGGCCCCTGGCACCTGGCACGGAT
GCTGGAGGCGATGGAGGCTTACCCCGTCAACGTCGGCTTCCTCGGCAAGGGCAACACCGTCTCGCACGAGGCGATGCTCT
CCCAGATCCGCGGCGGCGCCCTCGGGCTGAAGCTGCACGAGGACTGGGGGTCCACGCCGGCCGTCATCGACGCCGCGCTC
ACGGTGGCCGACCGGACCGGCATCCAGGTCGCCATCCACACGGACACGCTCAACGAGGCGGGCTTCGTCGGCGACACGCT
CGCCGCCATCGCCGGGCGGGGCATCCACTCGTACCACACCGAGGGCGCGGGCGGCGGGCACGCGCCGGACATCATGACCG
TGGTCTCCCGGCCCAACGTGCTGCCCAGCTCCACCAACCCGACCCGGCCGTTCACCGTCAACACCGCCGAGGAACACCTC
GACATGCTGATGGTGTGCCACCACCTCAACCCCGCCGTCCCCGAGGACCTGGCGTTCGCCGAGTCGCGGATCAGGCCGTC
CACGATCGGCGCCGAGGACATCCTGCACGACCTGGGCGCCATCTCCATCATCTCGTCCGACTCCCAGGCCATGGGCCGCG
TCGGCGAGGTCGTCCTGCGCACCTGGCAGACCGCGCACGTCATGAAGCGGCGCCGGGGCGCGCTGCCCGGTGACGGGCGC
GCGGACAACCACCGGGTGCGGCGCTACGTCGCCAAGTACACGATCAACCCGGCGCTCGCCCAGGGCCTCGCCCACGAGAT
CGGCTCCGTCGAGACCGGCAAGCTCGCCGACCTGGTGCTGTGGGAGCCCGCGTTCTTCGGGGTCAAACCGCTCCTGGTGA
TCAAGGGCGGCCAGATCGCGTACGCGCAGATGGGCGACGCCAACGCCTCCATCCCCACCCCGCAGCCCGTCCTGCCCCGG
CCGATGTACGGCGCGATCGGCCGGGCCCCGGCCGCCAACTCGGTCAACTTCGTGGCCCCCCTCGCCATCGAGGACGGGCT
GCCGGAGCGGCTGCGGCTGGGCAAGCGGTTCGCCGCGATCGAGTCGACCCGCGCCGTGACCAAGGCGGACATGCGGGAGA
ACGACGCGCTCCCGCAGGTGCGGATCGACCCCGACAGCTTCGCCGTGCACATCGACGGCGAACTGGTCGAGGCGGAGCCG
GCCACCGAACTGCCCATGGCCCAGCGCTACTTCCTCTTCTGA

Protein sequence :
MHEISRAAYADLFGPTTGDRIRLADTDLLIEIEEDLAGGPGRAGDEAVFGGGKVVRESMGQSRATRAEGTPDTVVTGVVV
VDHWGVVKADVGIRDGRITGIGKAGNPDTMDGVHPDLVIGPETEIIAGNGRILTAGAIDAHVHFICPQVADEALASGITT
LVGGGTGPAEGSKATTVTPGPWHLARMLEAMEAYPVNVGFLGKGNTVSHEAMLSQIRGGALGLKLHEDWGSTPAVIDAAL
TVADRTGIQVAIHTDTLNEAGFVGDTLAAIAGRGIHSYHTEGAGGGHAPDIMTVVSRPNVLPSSTNPTRPFTVNTAEEHL
DMLMVCHHLNPAVPEDLAFAESRIRPSTIGAEDILHDLGAISIISSDSQAMGRVGEVVLRTWQTAHVMKRRRGALPGDGR
ADNHRVRRYVAKYTINPALAQGLAHEIGSVETGKLADLVLWEPAFFGVKPLLVIKGGQIAYAQMGDANASIPTPQPVLPR
PMYGAIGRAPAANSVNFVAPLAIEDGLPERLRLGKRFAAIESTRAVTKADMRENDALPQVRIDPDSFAVHIDGELVEAEP
ATELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-169 61
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-169 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-155 59
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-156 59
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 6e-156 59
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-156 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC1 YP_008384925.1 urease subunit alpha VFG0270 Protein 2e-143 54