Gene Information

Name : B446_05995 (B446_05995)
Accession : YP_008384834.1
Strain : Streptomyces collinus Tu 365
Genome accession: NC_021985
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1444154 - 1445677 bp
Length : 1524 bp
Strand : +
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGACCCGTTACGCGGCGCCCGGCTCCGAGGGCGCGATCGTCTCCTACCAGGCGCGCTACGACCACTTCATCGGCGGTGA
GTACGTGCCGCCGGCGCGGGGGCAGTACTTCGAGAACCCGTCGCCGGTGAACGGGCAGCCGTTCACCGAGGTCGCGCGCG
GTACCGCGGAGGACGTCGAGCGGGCGCTGGACGCGGCGCACGCGGCCGCGCCCGGATGGGGCCGTACGTCGGTCACGGAG
CGGTCCGACATCCTGCGCAGGATCGCCGACCGCATGGAGGCGAACCTCGAATCGCTCGCCGTGGCGGAGAGCTGGGAGAA
CGGCAAGCCGGTGCGCGAGACGCTGGCGGCCGACATCCCGCTCGCCATCGACCACTTCCGCTACTTCGCGGGAGCGATCC
GGGCGCAGGAGGGCTCGCTGGGCGAGATCGACGACGACACGGTGGCGTACCACTTCCACGAGCCGCTCGGCGTGGTCGCG
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCCACCTGGAAGCTCGCCCCGGCGCTCGCCGCGGGCAACGCGGTGGT
CCTCAAGCCGGCGGAGCAGACCCCGGCGTCCATCCACTACTGGATGAGCCTGATCGCGGACCTGCTGCCGCCGGGCGTGG
TGAACATCGTCAACGGCTTCGGCGTGGAGGCGGGCAAGCCGCTGGCGTCCAGCCCGCGGGTGGCGAAGGTCGCGTTCACC
GGGGAGACCACGACCGGGCGGCTGATCATGCAGTACGCCTCGGAGAACATCAAGCCGGTCACGCTGGAGCTCGGCGGCAA
GTCGCCGAACATCTTCTTCGACGACGTCTGGGCGCAGGACGACGACTTCCGGGACAAGGCGCTCGAGGGCTTCACCATGT
TCGCGCTGAACCAGGGCGAGGTGTGCACCTGTCCCTCGCGGGCGCTGGTCCAGCGCGGGAACTACGCGGAGTTCCTGGAG
GCGGCCGTGGCCCGCACCCGGCAGATCAAGCCGGGGCACCCCCTCGACACGGACACGATGATCGGCGCGCAGGCCTCCAA
CGACCAGCTGGAGAAGATCCTCTCCTACCTGGACATCGGCCGGCAGGAGGGCGCCAAGGTCCTCACCGGTGGCGAGCGCG
TCGAGTACGACGGCGAGCTGAAGGGCGGCTACTACGTCCAGCCGACCATCTTCGAGGGCGACAACCGGATGCGGGTCTTC
CAGGAGGAGATCTTCGGTCCGGTGGTGTCGGTGGCGTCCTTCGACGACTTCGACGACGCCATCAAGATCGCGAACGACAC
GCTCTACGGGCTGGGCGCGGGCGTGTGGACCCGTGACATGAACACCGCCTACCGGGCAGGGCGTGCGATCCAGGCGGGCC
GTGTCTGGACCAACTGCTACCACGCCTACCCGGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGCGAG
ACGCACAAGATGATGCTCGAGCACTACCAGCAGACGAAGAACCTGCTGGTGAGCTACTCGCCGAAGAAGCTGGGCTTCTT
CTAG

Protein sequence :
MTRYAAPGSEGAIVSYQARYDHFIGGEYVPPARGQYFENPSPVNGQPFTEVARGTAEDVERALDAAHAAAPGWGRTSVTE
RSDILRRIADRMEANLESLAVAESWENGKPVRETLAADIPLAIDHFRYFAGAIRAQEGSLGEIDDDTVAYHFHEPLGVVA
QIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASIHYWMSLIADLLPPGVVNIVNGFGVEAGKPLASSPRVAKVAFT
GETTTGRLIMQYASENIKPVTLELGGKSPNIFFDDVWAQDDDFRDKALEGFTMFALNQGEVCTCPSRALVQRGNYAEFLE
AAVARTRQIKPGHPLDTDTMIGAQASNDQLEKILSYLDIGRQEGAKVLTGGERVEYDGELKGGYYVQPTIFEGDNRMRVF
QEEIFGPVVSVASFDDFDDAIKIANDTLYGLGAGVWTRDMNTAYRAGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRE
THKMMLEHYQQTKNLLVSYSPKKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-144 60
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-150 59
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-150 59
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-150 59
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-150 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
B446_05995 YP_008384834.1 aldehyde dehydrogenase VFG0082 Protein 7e-145 60