Gene Information

Name : I137_16345 (I137_16345)
Accession : YP_008382638.1
Strain : Salmonella enterica S06004
Genome accession: NC_021984
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3476908 - 3478803 bp
Length : 1896 bp
Strand : +
Note : catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Hom

DNA sequence :
ATGTCTACAACAACGTTAACCCGCCGCGAGCAGCGCGCTAAAGCCCAGCATTTTATCGATACGCTGGAAGGGACTGCCTT
TCCCAACTCGAAACGCATCTACGTGACCGGTTCGCAGCATGATATTCGCGTACCGATGCGTGAAATTCAACTGAGCCCGA
CGCTCATCGGCGGCAGTAAAGACAACCAGCAGTTTGAAGAGAACGAAGCCGTGCCGGTGTACGACACCTCCGGCCCCTAT
GGCGATCCTGAGGTGGCGATTAACGTCCAGCAGGGTCTGGCGAAACTGCGCCAGCCATGGATTGACGCACGTAACGATAG
CGAAGAATTAGACGACCGTAGCTCGGCTTATACCAGAGAACGTCTGGCCGACGATGGCCTGGACGATCTGCGTTTTACCG
GCCTGCTGACGCCAAAACGCGCTAAAGCGGGCAAGCGCATCACCCAGTTACACTACGCCCGCCAAGGGATCGTCACTCCC
GAAATGGAGTTCATCGCCATCCGTGAAAACATGGGCCGCGAGCGCATTTGCAGTGAAGTGCTGCGCCACCAGCATCCGGG
GATGAGCTTTGGCGCGCGCCTGCCGGAAAACATTACGCCGGAATTCGTGCGTGATGAAGTCGCCGCGGGCCGCGCGATTA
TTCCCGCCAACATCAACCACCCGGAATCGGAGCCGATGATTATTGGCCGCAACTTCCTGGTCAAAGTGAATGCCAACATC
GGTAACTCGGCGGTCACCTCCTCCATCGAAGAAGAGGTCGAGAAGCTGGTGTGGTCAACCCGCTGGGGCGCGGACACGGT
GATGGACCTCTCCACCGGTCGCTATATTCACGAAACCCGCGAATGGATCCTGCGTAACAGCCCGGTACCGATCGGCACCG
TCCCGATCTACCAGGCGCTGGAAAAGGTCAACGGGATCGCCGAAGATCTTACCTGGGAAGCGTTCCGCGACACGCTGCTG
GAGCAGGCCGAACAGGGCGTCGACTACTTCACCATCCACGCCGGCGTGCTGCTGCGCTACGTGCCGATGACCGCCAAACG
CCTGACCGGTATTGTCTCGCGCGGCGGTTCGATCATGGCGAAGTGGTGTCTCTCCCATCACAAAGAGAACTTCCTGTTCG
AACATTTCCGCGAGATCTGCGAAATCTGCGCCGCCTACGACGTTTCCCTGTCGTTGGGCGACGGCCTGCGCCCCGGCTCC
ATTCAGGACGCCAACGACGAAGCGCAGTTCTCCGAGCTGCATACGCTGGGCGAGCTGACCAAAATCGCCTGGGAATACGA
CGTGCAGGTGATGATTGAAGGCCCGGGTCATGTACCCATGCATATGATTCAGCGCAACATGACCGAAGAGCTGGAGAGCT
GCCATGAAGCACCGTTCTACACCTTAGGGCCATTGACTACCGATATCGCGCCGGGCTATGACCACTTCACCTCCGGGATC
GGTGCCGCGATGATCGGCTGGTTTGGCTGCGCGATGCTGTGTTATGTGACGCCGAAAGAGCATCTCGGCCTGCCGAACAA
AGAAGATGTGAAGCAGGGGCTAATCACCTACAAAATCGCCGCCCACGCCGCGGATTTAGCCAAAGGACATCCGGGCGCGC
AGATCCGCGATAACGCCATGTCGAAAGCGCGCTTCGAATTCCGCTGGGAAGATCAGTTTAACCTCGCGCTCGACCCGTTC
ACCGCCCGCGCTTATCACGATGAAACCCTGCCGCAGGAGTCCGGCAAAGTCGCCCACTTCTGTTCCATGTGCGGGCCGAA
ATTCTGCTCGATGAAAATCAGCCAGGAGGTCCGCGACTACGCCGCCGCGCAAGCCATTGAAGTCGGCATGGCGGATATGT
CGGAGAACTTCCGCGCCAAAGGCGGCGAAATTTATCTCAAACGGGAGGAAGCCTGA

Protein sequence :
MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNQQFEENEAVPVYDTSGPY
GDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRITQLHYARQGIVTP
EMEFIAIRENMGRERICSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 70