Gene Information

Name : lysS (I137_14510)
Accession : YP_008382296.1
Strain : Salmonella enterica S06004
Genome accession: NC_021984
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 3098297 - 3099814 bp
Length : 1518 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTGAACAAAACGCACAGGGCGCTGACGAGGTAGTCGATCTTAACAATGAAATGAAGGCACGTCGCGAGAAGCTGGC
TGCACTGCGTGAGCAGGGTATCCCGTTCCCGAACGATTTCCGTCGTGACCGTACCTCAGACCAACTGCACGCAGAGTTTG
ACGCGAAAGAAGCTGAAGAAATGGAAGCGCTGAATATTGAAGTGTCCGTCGCGGGCCGTATGATGACTCGCCGTATTATG
GGTAAGGCCTCTTTTGTTACCCTGCAAGACGTAGGCGGCCGCATTCAGCTGTATGTGGCGCGCGATGATCTGCCGGAAGG
CGTTTACAACGAGCAGTTCAAGAAGTGGGATCTTGGCGATATCCTCGGCGCGAAAGGTAAGCTGTTCAAAACCAAAACCG
GCGAGCTGTCTATCCACTGCACCGAACTGCGCCTGCTGACGAAAGCGCTGCGTCCGTTGCCGGATAAATTCCACGGCTTG
CAGGACCAGGAAGCGCGCTATCGCCAGCGTTATCTGGATCTCATCTCTAACGATGAATCCCGTAACACCTTCAAAACCCG
TTCGAAGATCCTGGCCGGTATTCGCCAGTTTATGGTTGCTCGCGGCTTTATGGAAGTCGAAACCCCGATGATGCAGGTGA
TCCCAGGCGGCGCGTCTGCCCGTCCGTTTATCACCCATCACAACGCGCTGGATCTGGACATGTACCTGCGTATCGCGCCG
GAACTGTACCTCAAGCGTCTGGTGGTTGGCGGCTTCGAACGCGTATTCGAAATTAACCGTAACTTCCGTAACGAAGGCAT
CTCCGTGCGCCATAATCCTGAGTTCACCATGATGGAACTCTATATGGCGTATGCGGACTACAAAGACCTGATCGAGCTGA
CGGAGTCTCTGTTCCGTACGCTGGCGCAGGATGTTCTGGGCACCACCCAGGTTCCGTACGGTGATGAAGTGTTTGACTTC
GGTAAGCCGTTCGAAAAACTGACCATGCGTGAAGCGATCAAGAAATATCGCCCGGAAACGGATATGGCTGATCTGGACAA
CTTCGATTCCGCGAAGGCGATTGCTGAAAGCATCGGCATTCACGTCGAGAAAAGCTGGGGTCTGGGCCGTATCGTCACCG
AGATCTTTGACGAAGTCGCTGAAGCGCATCTGATTCAGCCGACCTTCATCACCGAATATCCGGCTGAAGTGTCTCCGCTG
GCGCGTCGTAATGATGTGAACCCGGAAATCACTGACCGCTTCGAGTTCTTTATCGGCGGTCGTGAAATCGGTAATGGCTT
TAGCGAGTTGAACGATGCGGAAGACCAGGCGCAGCGTTTCCTGGATCAGGTTAATGCAAAAGCGGCGGGCGACGACGAAG
CCATGTTCTACGACGAAGACTACGTGACGGCGCTGGAACACGGGTTACCGCCGACAGCGGGTCTGGGAATTGGTATCGAC
CGTATGGTGATGCTGTTTACTAACAGCCACACGATTCGCGACGTTATTCTGTTCCCGGCGATGCGTCCGGTGAAATAA

Protein sequence :
MSEQNAQGADEVVDLNNEMKARREKLAALREQGIPFPNDFRRDRTSDQLHAEFDAKEAEEMEALNIEVSVAGRMMTRRIM
GKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
QDQEARYRQRYLDLISNDESRNTFKTRSKILAGIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAP
ELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQDVLGTTQVPYGDEVFDF
GKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPL
ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVNAKAAGDDEAMFYDEDYVTALEHGLPPTAGLGIGID
RMVMLFTNSHTIRDVILFPAMRPVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-170 69

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_008382296.1 lysyl-tRNA synthetase VFG1668 Protein 3e-170 69