Gene Information

Name : I137_01135 (I137_01135)
Accession : YP_008379812.1
Strain : Salmonella enterica S06004
Genome accession: NC_021984
Putative virulence/resistance : Virulence
Product : lysine decarboxylase CadA
Function : -
COG functional category : -
COG ID : -
EC number : 4.1.1.18
Position : 277258 - 279399 bp
Length : 2142 bp
Strand : +
Note : constitutive; catalyzes the formation of cadaverine from lysine; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGAACATCATCGCCATTATGGGGCCGCACGGGGTTTATTATAAAGATGAACCCATCAAGGAGCTTGAGCGTGCATTACA
ATCCCTGGGATTTCAAATTATCTGGCCGCAAAATAGCGTTGACTTGTTGAAGTTTATTGAACATAACCCGCGCATCTGCG
GCGTTATTTTTGACTGGGATGAATACAGTCTCGACCTTTGTAGCGAAATCAACCAGCTAAATGAATACCTTCCTCTCTAC
GCCTTTATCAATACCAACTCCACGCTGGACGTTAGCGTTCACGATATGCGCATGGCGCTGTGGTTTTTTGAGTATGCGTT
GGGGCTGGCTGAAGATATCGCGACGCGCATTCATCAATATACAAACGAATATCTCGATAATATTACGCCGCCGTTTACCA
AAGCGCTGTTTACCTACGCCAAAGAAGGAAAATATACCTTTTGTACGCCGGGTCATATGGCGGGAACGGCGTATCAGAAA
AGCCCGCCAGGCTGCCTGTTTTATGACTTTTTTGGCGGCAATACCTTAAAAGCTGATGTGTCGATTTCGGTGACTGAACT
GGGATCGCTGCTGGATCACACCGGGCCGCATCTGGAAGCGGAAGAGTATATCGCCCGTACTTTTGGCGCCGAGCAGAGCT
ATATGGTGACGAACGGTACGTCGACCTCGAATAAAATTGTCGGTATGTATGCCGCGCCTGCGGGAAGTACGCTACTCATT
GATCGTAATTGTCATAAATCGCTGGCGCATTTGCTGATGATGAGCGATGTGGTGCCTCTCTGGTTGAAGCCGACGCGCAA
TGCGCTCGGCATTCTCGGCGGTATTCCCCGAAGGGAATTTACCCGTGCAAGCATCGAAAGCAAGATAGAGGAGACCCCTC
AGGCGCAATGGCCGGTTCATGCGGTTATCACCAATTCGACTTACGATGGTCTGCTGTATAACACTAACTGGATCAAGCAG
ATGCTGGACGTTCCCTCGATCCATTTTGATTCCGCCTGGGTACCCTATACCCATTTCCATCCGATCTACCAGGGGAAAAG
CGGGATGAGCGGCGATCGGGTGCCTGGAAAAGTGATTTTCGAAACGCAATCCACCCATAAAATGCTGGCGGCTTTTTCGC
AGGCGTCGCTTATTCATATCAAAGGGGAATATGACGAAGAGACGTTTAACGAAGCGTTTATGATGCACACTTCTACATCG
CCGAGCTATCCCATTGTCGCCTCTATCGAGACCGCGGCGGCGATGCTGCGCGGCAATCCAGGGAAAAGATTGATTAATCG
TTCGGTGGAACGGGCGCTCCATTTTCGTAAAGAAGTACAGCGGTTACGTGAAGAGTCCGATAGCTGGTTCTTTGATATCT
GGCAGCCGGAAGAGGTTGATGAGGCCGAATGCTGGCCGGTCACGCCGGGAGAAACCTGGCATGGCTTCACCGATGCTGAT
GACGATCATATGTTCCTCGATCCGGTTAAGGTGACAATCCTGACGCCGGGGATGGATGAACAGGGCAACATGAGCGAAGA
GGGGATACCCGCCGCGCTGGTGGCGAAGTTCCTTGATGAGCGAGGCGTGGTGGTGGAAAAAACCGGGCCGTATAATCTGC
TGTTTTTGTTCAGCATAGGGATTGATAAGACCCGTGCGATGGGGCTGCTGCGCGGACTGACGGAATTTAAACGCGCCTAC
GATCTTAACCTGCGCGTCAAAAATATGTTGCCGGATCTGTATGCGGAAGATCCGGATTTTTATCGCAATATGCGCATTCA
GGATCTGGCGCAGGGGATCCATAAACTGATCCGCCAGCACGATCTTCCGGGGCTGATGCTGCGGGCGTTCGAGGTTTTAC
CGGAGATGATCATGACCCCGCACCAGGCCTGGCAGCGTCAGATCAAAGGCGAGGTGGAAACCGTGGCGCTCGATCAACTG
CCAGGGCGCGTTTCCGCGAATATGATCCTGCCTTATCCGCCAGGCGTTCCGCTGTTGATGCCCGGCGAGAGGATCACGCA
ACAGAGTCGGGCCGTGCTCGATTTTCTGCTGATGCTCTGCTCGATTGGCCAGCATTATCCCGGTTTTGAAACGGATATTC
ACGGCGCGAAACGGAATGAAGACGGGGTGTACCAGGTACGAGTCTTAAAACACGCCTGTTAG

Protein sequence :
MNIIAIMGPHGVYYKDEPIKELERALQSLGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSEINQLNEYLPLY
AFINTNSTLDVSVHDMRMALWFFEYALGLAEDIATRIHQYTNEYLDNITPPFTKALFTYAKEGKYTFCTPGHMAGTAYQK
SPPGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYMVTNGTSTSNKIVGMYAAPAGSTLLI
DRNCHKSLAHLLMMSDVVPLWLKPTRNALGILGGIPRREFTRASIESKIEETPQAQWPVHAVITNSTYDGLLYNTNWIKQ
MLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGDRVPGKVIFETQSTHKMLAAFSQASLIHIKGEYDEETFNEAFMMHTSTS
PSYPIVASIETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDSWFFDIWQPEEVDEAECWPVTPGETWHGFTDAD
DDHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGVVVEKTGPYNLLFLFSIGIDKTRAMGLLRGLTEFKRAY
DLNLRVKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRQHDLPGLMLRAFEVLPEMIMTPHQAWQRQIKGEVETVALDQL
PGRVSANMILPYPPGVPLLMPGERITQQSRAVLDFLLMLCSIGQHYPGFETDIHGAKRNEDGVYQVRVLKHAC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 71
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
I137_01135 YP_008379812.1 lysine decarboxylase CadA VFG1670 Protein 0.0 62