Gene Information

Name : I137_05680 (I137_05680)
Accession : YP_008380646.1
Strain : Salmonella enterica S06004
Genome accession: NC_021984
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1267514 - 1268815 bp
Length : 1302 bp
Strand : +
Note : Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGAAGAATGAATTGATGCAACGTCTGAGGCTGAAATATCCGCCCCCCGATGGTTATTGTCGATGGGGCCGAATTCAGGA
TGTCAGCGCAACGTTGTTAAATGCGTGGTTGCCTGGGGTATTTATGGGTGAGTTGTGCTGTATAAAGCCTGGAGAAGAAC
TTGCTGAAGTCGTGGGGATTAATGGCAGCAAAGCTTTGCTATCTCCTTTTACGAGTACAATCGGACTTCACTGCGGGCAG
CAAGTGATGGCCTTAAGGCGACGCCATCAGGTTCCCGTGGGCGAAGCGTTATTAGGGCGAGTCATTGATGGTTTTGGTCG
TCCCCTTGATGGCCGCGAACTGCCCGACGTCTGCTGGAAAGACTATGATGCAATGCCTCCTCCCGCAATGGTTCGACAGC
CTATCACTCAACCATTAATGACGGGGATTCGCGCTATTGATAGCGTTGCAACCTGTGGCGAAGGGCAACGAGTGGGTATT
TTTTCTGCTCCTGGCGTGGGGAAAAGCACGCTTCTGGCGATGCTGTGTAATGCGCCAGACGCAGACAGCAATGTTCTGGT
GTTAATTGGTGAACGTGGACGAGAAGTCCGCGAATTCATCGATTTTACACTGTCTGAAGAGACCCGAAAACGCTGTGTCA
TTGTTGTCGCAACCTCTGACAGCCCCGCCTTAGAGCGCGTGAGGGCGCTGTTTGTGGCTACCACGATAGCAGAATTTTTT
CGCGATAATGGAAAGCGAGTCGTCTTGCTTGCCGACTCACTGACGCGTTATGCCAGGGCCGCACGAGAAATCGCTCTGGC
CGCCGGAGAGACCGCAGTTTCTGGAGAATATCCGCCAGGCGTATTTAGTGCATTGCCACGACTTTTAGAACGTACAGGAA
TGGGGGAAAAAGGCAGTATTACCGCATTTTATACGGTACTGGTGGAAGGCGATGATATGAATGAGCCGTTGGCGGATGAA
GTCCGTTCACTACTTGATGGACATATTGTGCTATCCCGGCGGCTTGCAGAGAGGGGGCATTATCCTGCCATTGACGTGCT
GGCAACGCTCAGCCGCGTTTTTCCAGTCGTTACCAGCCATGAGCATCGTCAACTGGCGGCGATATTGCGGCGGCGCCTGG
CGCTTTACCAGGAGGTTGAACTGTTAATACGCATTGGGGAATACCAGCGAGGAGTTGATACTGATACTGACAAAGCCATT
GATACCTATCCGGATATTTGCACATTTTTGCGACAAAGTAAGGATGAAGTATGCGGACCCGAGCTACTTATAGAAAAATT
ACACCAAATACTCACCGAGTGA

Protein sequence :
MKNELMQRLRLKYPPPDGYCRWGRIQDVSATLLNAWLPGVFMGELCCIKPGEELAEVVGINGSKALLSPFTSTIGLHCGQ
QVMALRRRHQVPVGEALLGRVIDGFGRPLDGRELPDVCWKDYDAMPPPAMVRQPITQPLMTGIRAIDSVATCGEGQRVGI
FSAPGVGKSTLLAMLCNAPDADSNVLVLIGERGREVREFIDFTLSEETRKRCVIVVATSDSPALERVRALFVATTIAEFF
RDNGKRVVLLADSLTRYARAAREIALAAGETAVSGEYPPGVFSALPRLLERTGMGEKGSITAFYTVLVEGDDMNEPLADE
VRSLLDGHIVLSRRLAERGHYPAIDVLATLSRVFPVVTSHEHRQLAAILRRRLALYQEVELLIRIGEYQRGVDTDTDKAI
DTYPDICTFLRQSKDEVCGPELLIEKLHQILTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 0.0 99
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 0.0 99
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 0.0 99
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 0.0 99
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 0.0 99
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-106 59
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-92 55
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-72 52
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-69 51
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 6e-71 51
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-73 51
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-73 51
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-87 51
escN AAC38383.1 EscN Virulence LEE Protein 1e-86 51
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-83 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-83 51
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 6e-73 51
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-85 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-85 50
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-70 50
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-70 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-83 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-84 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-84 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-83 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-84 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 50
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-78 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-86 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-86 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-86 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 7e-87 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-86 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 7e-87 50
escN CAI43874.1 EscN protein Virulence LEE Protein 5e-87 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 7e-87 50
escN AAK26715.1 EscN Virulence LEE Protein 1e-86 50
escN AAL57542.1 EscN Virulence LEE Protein 1e-86 50
escN AAC31513.1 L0034 Virulence LEE Protein 1e-86 50
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-71 48
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-72 48
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-71 48
invC AAS66861.1 InvC Not tested SSR-2 Protein 4e-62 47
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-64 45
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-64 45
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-64 45
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-64 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-65 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-61 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
I137_05680 YP_008380646.1 type III secretion system ATPase VFG0515 Protein 0.0 99
I137_05680 YP_008380646.1 type III secretion system ATPase VFG0390 Protein 5e-90 57
I137_05680 YP_008380646.1 type III secretion system ATPase VFG0192 Protein 5e-92 55
I137_05680 YP_008380646.1 type III secretion system ATPase VFG0048 Protein 3e-88 53
I137_05680 YP_008380646.1 type III secretion system ATPase VFG0730 Protein 7e-87 51
I137_05680 YP_008380646.1 type III secretion system ATPase VFG2144 Protein 1e-77 51
I137_05680 YP_008380646.1 type III secretion system ATPase VFG1254 Protein 9e-72 51
I137_05680 YP_008380646.1 type III secretion system ATPase VFG0812 Protein 7e-87 50
I137_05680 YP_008380646.1 type III secretion system ATPase VFG2499 Protein 4e-63 47
I137_05680 YP_008380646.1 type III secretion system ATPase VFG1008 Protein 2e-66 45
I137_05680 YP_008380646.1 type III secretion system ATPase VFG0555 Protein 3e-64 45
I137_05680 YP_008380646.1 type III secretion system ATPase VFG1778 Protein 2e-63 45
I137_05680 YP_008380646.1 type III secretion system ATPase VFG2459 Protein 1e-63 43
I137_05680 YP_008380646.1 type III secretion system ATPase VFG2331 Protein 3e-62 43