Gene Information

Name : CYCME_2461 (CYCME_2461)
Accession : YP_008375125.1
Strain : Cycloclasticus zancles 7-ME
Genome accession: NC_021917
Putative virulence/resistance : Virulence
Product : Type I site-specific restriction-modification system, R (restriction) subunit-related helicase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2496887 - 2499913 bp
Length : 3027 bp
Strand : -
Note : -

DNA sequence :
ATGGTTAGCCAAACAAACGAACAGGCGCTGGAGGCCGCAATCGAGACAGCCTTGGTGGGTAGCTGTTTGGAAGAGCGCAA
AAACCAAGTAAAAGAAGTGATCCCCGACTATGGTAATAAATATTACCAGCCGGGTAGCCCTATCGACTTTAATAAGCAGT
ATGCGCTCGATGAGCGTTTCTTCTGGGCGTTTTTAGAAAAAACGCAGGAAGATGAGCTTGAAAAGATCAAACGCAATAAC
CCTAACGACTGGCAACGCAAAATATACGAGCGCTTTGACCGGCTCATCAAAAAACACGGTATTTTACATCTGCTCAAGAA
AGGCTTGAGCGTTGACGATGCTCACTTCAATTTAATGTATCCAGCACCGCTGGCTAGCAGTAGTGAGAAGGTTAAACAGA
ACTTTTCTGAAAACCTGTTTAGCTGTACCCGCCAATTACGTTATTCGCAGGCTAATCCGCTGCAAGAAATTGATATGGTT
TTGTTTATCAATGGTATTCCATTGATTACCCTAGAATTGAAGAACGCTTGGACAAATCAAACTGCCCGATACCACGGGCA
AAAACAATACCGTGAAGATCGAGATACGAATCAACCACTTCTGAATTTTGGTCGCTGTCTGGTGCATATGGCGGTAGATA
CCGATGAAGTCTATATGACGACCAAGTTGGCAGGTAAGGCGACGTTCTTCTTGCCGTTCAACAAAGGGCATAACCTCGGT
CAAGGCAATCCACCAAACCAAACAGGGCATAAAACGGCTTATTTATGGGAAGAGGTTTTCACCAAAGAAAGCTTAGCCAA
TATTATTCAGCACTTTGTAAGACTGGACGGTAGCAGCAAAGACCCACTTAACAAGCGCACTTTGTTTTTCCCGCGTTATC
ATCAAATGGATGTGGTACGAAAGTTGGTTAACGATGCTTCTGAGAATGGCGTTGGCCAAACATACTTAATTCAGCATTCG
GCGGGTTCTGGTAAGTCTAATTCAATCACTTGGGCTGCGTATCAGCTTATTGAAACTTACCCTGCTAACGAGGGTGTTCA
AGGTAGCCGAGGTTTAGATCAGCCATTATTTGATTCAGTGATTGTTGTGACTGACAGACGCTTACTCGATAAGCAGCTTC
GCGATAACATCAAAGACTTCTCGGAAGTGAAGAACATTGTTGCGCCAGCCCATAAATCGTCGGAGCTTAAGTCTGCACTT
GAGAATGGTAAGAAGATTATCATCACCACTATTCAGAAATTCCCATTCATTATTGATGGTATTGCCGATCTTAGCGATAA
GCGCTTTGCTGTCATTATTGATGAGGCGCACAGTTCGCAGTCAGGTTCAGCCCACGACAACATGAACCGTGCAATGGGTA
AATCTGAGGTGGAAGGGGCGGAAGACGCTCAAGACAAGATTCTACAGGCGATGAAATCACGCAAGATGCGTGGCAATGCC
TCATATTTAGCGTTTACCGCTACACCTAAAAATACCACCCTAGAAAAGTTTGGACAACAACAGCCTGATGGCAGCTTTGA
GCCATTCCATTTGTACACTATGAAGCAGGCGATTGAAGAAGGTTTCATTCTTGATGTGCTGGCTAATTACACGACTTACA
AAAGCTATTACGAAATCGAAAAGTCGATTCAAGACAACCCTGAATTTGATACCAAGAAAGCGCAAAAAAAACTCAGGGCT
TACGTTGAGAGCAGCCAACATACGATAGATACCAAAGCTGAGATTATGCTGGAGCATTTTGTGCCGCATGTCGTCAACGC
CAAGAAGCTTAAAGGCAAAGGTAAAGGTATGGTAGTGACACAGAATATTGAAACGGCTATTCGCTATTACAAAGCCATAA
CACGATTCCTTGAGGAACAGGGCAACCCCTTTAAGGCCGTGATTGCTTTCTCGGGCGAGAAGGAAGTAGATGGTATCAAA
TACACTGAAGCTGAAATGAATGGCTTTGCTGAGAATGAAACCAAGGATAAATTCGATAAAGACGAATATCGCCTTCTCGT
AGTGGCAAATAAGTATCTCACAGGCTTTGATCAACCTAAGCTCTGCGCGATGTATGTAGATAAGAAGCTGGCGAGTGTTT
TGTGTGTGCAGGCGCTATCGCGTTTAAACAGGTCAGCTCCTAAGCTAGGCAAGAAAACGGAAGATCTTTTCGTGCTAGAT
TTTTTCAATTCTATTGAAGAAATTAAAACGGCATTTGATCCATTCTATACAGCAACCTCACTGTCTGAAGCGACTGATGT
CAATGTACTCCATGAATTAAAAGATGAAATGGATGATGTAGGTGTTTATGAATGGACGGAAGTTGAAGAGTTTGTAAAAC
GGTATTTTGACAATGAAGATGCACAACGTCTAAGCCCCATAATCGATATTGCCGCAGCCCGATTCAATATTGAATTGGAG
CTAGAAAATGAAGCCAAAATCGACTTCAAAATCAAAGCCAAGCAGTTTGTTAAAATCTACGGCCAGATGGCTTCAATTAT
GTCCTATGAAATAGCTGTATGGGAAAAACTATTCTGGTTCTTAAAGTTCCTGATCCCCAAGCTTAAAGTTCAAGATCCTG
ATGCTGAATTATTAGATGAATTATTGGATTCAGTTGATCTGAGCTCATACGGTCTTCAAAGAGTTAAGCTAAGCCACACT
ATTGGTTTGGACGGAGAAGAAACAGAGTTAGATCCACAAAACCCTAACCCAAGAGGGGCGCACGGTGGCGACAAAGAAAC
CAACCCATTGGATGACATCATATACACGTTCAATGAACGCTGGTTCCAAGGTTGGAGTGCAACACCCGAAGAGCAACGTA
TTAAGTTTGTAAACATAGCAGATAGCGTAAAAGCGCACCCAGATTATGAAGACAAATATAAAAACAACGCCGATCCACAT
AACCGTGAATTGGCATTCGAAAAAATATTAAAAGAAATAATGCTTCAGCGCCGCAAAGACGAGCTAGAGCTATACAAGTT
GTTTGCTGGTGATGATGCCTTTAAGTCGTCTTGGAAGCAGAGTATTCAGCGCATTGTGGATATGTAG

Protein sequence :
MVSQTNEQALEAAIETALVGSCLEERKNQVKEVIPDYGNKYYQPGSPIDFNKQYALDERFFWAFLEKTQEDELEKIKRNN
PNDWQRKIYERFDRLIKKHGILHLLKKGLSVDDAHFNLMYPAPLASSSEKVKQNFSENLFSCTRQLRYSQANPLQEIDMV
LFINGIPLITLELKNAWTNQTARYHGQKQYREDRDTNQPLLNFGRCLVHMAVDTDEVYMTTKLAGKATFFLPFNKGHNLG
QGNPPNQTGHKTAYLWEEVFTKESLANIIQHFVRLDGSSKDPLNKRTLFFPRYHQMDVVRKLVNDASENGVGQTYLIQHS
AGSGKSNSITWAAYQLIETYPANEGVQGSRGLDQPLFDSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPAHKSSELKSAL
ENGKKIIITTIQKFPFIIDGIADLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKSEVEGAEDAQDKILQAMKSRKMRGNA
SYLAFTATPKNTTLEKFGQQQPDGSFEPFHLYTMKQAIEEGFILDVLANYTTYKSYYEIEKSIQDNPEFDTKKAQKKLRA
YVESSQHTIDTKAEIMLEHFVPHVVNAKKLKGKGKGMVVTQNIETAIRYYKAITRFLEEQGNPFKAVIAFSGEKEVDGIK
YTEAEMNGFAENETKDKFDKDEYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKLGKKTEDLFVLD
FFNSIEEIKTAFDPFYTATSLSEATDVNVLHELKDEMDDVGVYEWTEVEEFVKRYFDNEDAQRLSPIIDIAAARFNIELE
LENEAKIDFKIKAKQFVKIYGQMASIMSYEIAVWEKLFWFLKFLIPKLKVQDPDAELLDELLDSVDLSSYGLQRVKLSHT
IGLDGEETELDPQNPNPRGAHGGDKETNPLDDIIYTFNERWFQGWSATPEEQRIKFVNIADSVKAHPDYEDKYKNNADPH
NRELAFEKILKEIMLQRRKDELELYKLFAGDDAFKSSWKQSIQRIVDM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1765 NP_231400.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 79
VC0395_A1363 YP_001217306.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 79
VPI2_0013c ACA01830.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 79
SAS0025 YP_042158.1 type I restriction enzyme protein Not tested SCC476 Protein 7e-125 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CYCME_2461 YP_008375125.1 Type I site-specific restriction-modification system, R (restriction) subunit-related helicase VFG1098 Protein 0.0 79