Gene Information

Name : CYCME_0209 (CYCME_0209)
Accession : YP_008372910.1
Strain : Cycloclasticus zancles 7-ME
Genome accession: NC_021917
Putative virulence/resistance : Resistance
Product : Mercuric reductase MerA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 205925 - 207373 bp
Length : 1449 bp
Strand : -
Note : -

DNA sequence :
ATGACTAATCAAGAAAATAACGAACAATCATCCTGTTGTACCGGCAACAAGGAATCATTGCATGTTGCCATTGTTGGCAG
TGGTTCTGGGGCGTTTGCCTGTGCCATCAAGGCAGCGGAAGGCGGTGCCAAGGTTACCATCATCGAAGGGGCTGACGTGA
TTGGCGGCTGCTGTGTCAATGTTGGTTGTGTGCCTTCTAAAATTTTAATCCGGGCGGCGCAATTGGCGCAGCAACAACGC
CATAACCCCTTTGCCGGTCTGGCAAATCACACGCCCGAATTAAGTCGTGCTCTGCTGGCGCAACAACAAACGGCGCGTGT
AGAAGAATTGCGGGCCGCCAAATACCAAAATATTCTCGATTCTAACCCGGCATTGAGTTTGGTCAAAGGTTATGCGAAAT
TTAAAGACGCAAATACCTTAATCGTCAGCAAGGCCGATGGTTCTGAACAAGATATTCACGCTGATAAGATTTTGATTGCC
ACCGGTTCAACACCGACTATTCCACCGATTGATGGTCTCGTGGATACTCCTTATTGGACATCCACCGAAGCGCTGTTTGC
CAAGAACCTGCCACAACACCTGATGGTGATCGGTTCGTCTGTTGTCGCACTGGAAATTGCCCAGGCTTACCGTCGTTTGG
GCAGTGAAGTGACGGTATTGGCACGTCACACCTTGCTCTATCGGGAAGACCCGCTACTCGGTGAAAAACTGGCTGAATGC
TTTGAAAAAGAAGGGATGCGCATTCTCAGCGATACTCGAGCGTCCAGCGTTTCCTACGACGGTCAGCGGTTCACTCTTGA
ATCCAACGCAGGCACCTTGATTTGTGACCAATTGTTGATCAGCACCGGGCGTCATGCCAATACGGCCCAACTGAATCTGG
ATACGGTCGGTGTCAACACCGAGAAAAACGGTGAGATCATCGTCAATGAGCGCATGGAAACCAGCGTCCCCGGTATTTAT
GCGGCGGGTGATTGCTCTAATATGCCGCAATTTGTCTATGTCGCGGCAGCAGCGGGTAGTCGTGCCGGGGTCAATATGAC
GGGAGGGGATGCCAAACTGGATCTATCCACCATGCCAGCGGTGATCTTTACGGATCCTCAGGTGGCCACAGTCGGACTGA
CCGAAAAGCAGGCCAACGCGCAGGGTATTGACACCGACAGTCGCGTATTGGATATGGAAAACGTGCCGCGAGCGCTGGCC
AACTTTGAAACTGACGGCTTTATCAAGCTCGTCGTTGAAATGGCAACCGGACGCTTGATCGGCGCGCAGATTTTGGCTCA
CGAAGGCGGTGAGCTCATTCAAAGCGCAGTCTTAGCGATCCGTAATCGCATGACTGTCATCGACCTGGGCGATCAACTGT
TTCCCTACTTAACCATGGTGGAAGGTTTGAAACTCTGTGCACAAACTTTCAACAAGGATGTGAAAGAACTGTCCTGCTGC
GCTGGATAA

Protein sequence :
MTNQENNEQSSCCTGNKESLHVAIVGSGSGAFACAIKAAEGGAKVTIIEGADVIGGCCVNVGCVPSKILIRAAQLAQQQR
HNPFAGLANHTPELSRALLAQQQTARVEELRAAKYQNILDSNPALSLVKGYAKFKDANTLIVSKADGSEQDIHADKILIA
TGSTPTIPPIDGLVDTPYWTSTEALFAKNLPQHLMVIGSSVVALEIAQAYRRLGSEVTVLARHTLLYREDPLLGEKLAEC
FEKEGMRILSDTRASSVSYDGQRFTLESNAGTLICDQLLISTGRHANTAQLNLDTVGVNTEKNGEIIVNERMETSVPGIY
AAGDCSNMPQFVYVAAAAGSRAGVNMTGGDAKLDLSTMPAVIFTDPQVATVGLTEKQANAQGIDTDSRVLDMENVPRALA
NFETDGFIKLVVEMATGRLIGAQILAHEGGELIQSAVLAIRNRMTVIDLGDQLFPYLTMVEGLKLCAQTFNKDVKELSCC
AG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 1e-118 61
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 1e-118 61
merA AFG30120.1 MerA Not tested PAGI-2 Protein 1e-118 61
merA AGK07021.1 MerA Not tested SGI1 Protein 1e-119 60
merA AGK07079.1 MerA Not tested SGI1 Protein 1e-119 60
merA ABQ57371.1 MerA Not tested SGI1 Protein 1e-119 60
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 4e-118 60
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 2e-122 60
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 2e-118 60
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-114 58
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 1e-74 44
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 1e-74 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CYCME_0209 YP_008372910.1 Mercuric reductase MerA BAC0652 Protein 4e-119 60
CYCME_0209 YP_008372910.1 Mercuric reductase MerA BAC0650 Protein 3e-118 59
CYCME_0209 YP_008372910.1 Mercuric reductase MerA BAC0653 Protein 2e-120 58
CYCME_0209 YP_008372910.1 Mercuric reductase MerA BAC0651 Protein 6e-75 44
CYCME_0209 YP_008372910.1 Mercuric reductase MerA BAC0224 Protein 5e-69 42