Gene Information

Name : guaA (REMIM1_CH00301)
Accession : YP_008363098.1
Strain : Rhizobium etli Mim1
Genome accession: NC_021905
Putative virulence/resistance : Unknown
Product : GMP synthase (glutamine-hydrolyzing)
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 302030 - 303592 bp
Length : 1563 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAGACAGCACATCCCGACTCCGTTCTCATCGTCGATTTCGGCAGCCAGGTGACCCAGCTCATCGCACGGCGCGT
GCGCGAGGCCGGCGTCTATTGCGAGATCGTTCCCTTTCAATCTGCCGAAGAAGGCTTCAAGCGCCTACAGCCGAAGGCCG
TGATCCTCTCCGGCAGCCCGGCTTCCACCGTGGACGAGGGATCGCCGCGAGCGCCTCAGATCATCTTCGACAGTGGCCTG
CCGGTCTTCGGCATCTGCTACGGTCAGCAGACGATGTGCATGCAGCTCGGCGGCAAGGTCGAAAGCGGCCATCACCGTGA
ATTCGGACGCGCCTTTCTGGATGTCGACAAGGATTGCGAGCTGTTCGAAGGCCTCTGGTCCTCCGGCTCGCGCCATCAGG
TGTGGATGAGCCATGGCGACCGCGTCACCGCGCTGCCCGATGGTTTCAAGGTGGTCGCCACCTCTTCCAATGCGCCCTTC
GCCTTCATCGCCGACGAGAAGCGCAAATATTACGGCGTGCAATTCCACCCCGAGGTCGTCCATACGCCTGACGGCGCCAA
GCTGATCGGCAACTTCATTCACAATGTCGCTGGCATCAGGGGCGACTGGTCGATGTCGGCCTATCGCCAAAAGGCGGTCG
AAGAGATCCGCAAGCAGGTGGGCGACAAGCGCGTCATCTGCGCGCTTTCGGGCGGCGTCGACAGCTCCGTCGCCGCGCTC
CTGATCCACGAGGCCGTGGGCGACCAACTGACCTGCATCCTGGTCGACCACGGCCTGATGCGGAAGGACGAGGCGGCCAA
TGTCGTCGCCATGTTCCGCGAGCACTACAATCTGCATCTGCTGCACGTCGATGCCTCGGACCGCTTCATCGGCGAGCTCG
AAGGCGTCAGCGACCCGGAAACCAAGCGCAAGATCATCGGCCGGCTCTTCATCGAGACCTTCGAGGAAGAGGCAAAGAAA
CTCGGCGGCGCCGATTTCCTCGGCCAGGGCACGCTCTATCCTGACGTGATCGAGAGCGTTTCCTTCACCGGCGGCCCGTC
GGTGACGATCAAGTCGCACCATAATGTCGGCGGCCTGCCGGAACGCATGAAGATGCAGCTCGTCGAGCCGCTGCGCGAAC
TCTTCAAGGACGAGGTGCGCGCGCTCGGCCGTGAACTCGGCCTGCCAGACAGCTTCATCGGCCGTCATCCCTTCCCCGGC
CCCGGCCTTGCCATCCGTTGCCCCGGCGGCATCACCCGCGAGAAGCTCGAGATCCTGCGCGAGGCCGATGCGATCTATCT
CGACGAAATCCGCAAGGCCGGCCTCTACGACGCCATCTGGCAGGCCTTCGCCGTGCTGCTCCCGGTCCAGACCGTCGGCG
TCATGGGCGACGGGCGCACCTATGAATTCGTCTGCGCGCTGCGCGCCGTCACCTCCGTCGACGGCATGACCGCCGATTTC
TACCACTACGACATGGAATTCCTCGGCCGCGCCGCCACCCGCATCATCAATGAGGTGCGCGGCATCAACCGTGTGGTCTA
TGACGTCACGTCAAAGCCGCCCGGCACCATCGAGTGGGAGTGA

Protein sequence :
MTQTAHPDSVLIVDFGSQVTQLIARRVREAGVYCEIVPFQSAEEGFKRLQPKAVILSGSPASTVDEGSPRAPQIIFDSGL
PVFGICYGQQTMCMQLGGKVESGHHREFGRAFLDVDKDCELFEGLWSSGSRHQVWMSHGDRVTALPDGFKVVATSSNAPF
AFIADEKRKYYGVQFHPEVVHTPDGAKLIGNFIHNVAGIRGDWSMSAYRQKAVEEIRKQVGDKRVICALSGGVDSSVAAL
LIHEAVGDQLTCILVDHGLMRKDEAANVVAMFREHYNLHLLHVDASDRFIGELEGVSDPETKRKIIGRLFIETFEEEAKK
LGGADFLGQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRALGRELGLPDSFIGRHPFPG
PGLAIRCPGGITREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADF
YHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-137 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-137 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-137 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-116 50