Gene Information

Name : CTRC122_04035 (CTRC122_04035)
Accession : YP_008348545.1
Strain : Chlamydia trachomatis RC-J(s)/122
Genome accession: NC_021891
Putative virulence/resistance : Resistance
Product : tetracycline resistance structural protein TetA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 872499 - 873689 bp
Length : 1191 bp
Strand : -
Note : COG0477 Permeases of the major facilitator superfamily

DNA sequence :
ATGAAATCTAACAATGCGCTCATCGTCATCCTCGCCACCGTCACCCTGGATGCTGTAGGCATAGGCTTGGTTATGCCGGT
ACTGCCGGGCCTCTTGCGGGATATCGTCCATTCCGACAGCATCGCCAGTCACTATGGCGTGCTGCTAGCGCTATATGCGT
TGATGCAATTTCTATGCGCACCCGTTCTCGGAGCACTGTCCGACCGCTTTGGCCGCCGCCCAGTCCTGCTCGCTTCGCTA
CTTGGAGCCACTATCGACTACGCGATCATGGCGACCACACCCGTCCTGTGGATCCTCTACGCCGGACGCATCGTGGCCGG
CATCACCGGCGCCACAGGTGCGGTTGCTGGCGCCTATATCGCCGACATCACCGATGGGGAAGATCGGGCTCGCCACTTCG
GGCTCATGAGCGCTTGTTTCGGCGTGGGTATGGTGGCAGGCCCCGTGGCCGGGGGACTGTTGGGCGCCATCTCCTTGCAT
GCACCATTCCTTGCGGCGGCGGTGCTCAACGGCCTCAACCTACTACTGGGCTGCTTCCTAATGCAGGAGTCGCATAAGGG
AGAGCGTCGACCGATGCCCTTGAGAGCCTTCAACCCAGTCAGCTCCTTCCGGTGGGCGCGGGGCATGACTATCGTCGCCG
CACTTATGACTGTCTTCTTTATCATGCAACTCGTAGGACAGGTGCCGGCAGCGCTCTGGGTCATTTTCGGCGAGGACCGC
TTTCGCTGGAGCGCGACGATGATCGGCCTGTCGCTTGCGGTATTCGGAATCTTGCACGCCCTCGCTCAAGCCTTCGTCAC
TGGTCCCGCCACCAAACGTTTCGGCGAGAAGCAGGCCATTATCGCCGGCATGGCGGCCGACGCGCTGGGCTACGTCTTGC
TGGCGTTCGCGACGCGAGGCTGGATGGCCTTCCCCATTATGATTCTTCTCGCTTCCAGCGGCATCGGGATGCCCGCGTTG
CAGGCCATGCTGTCCAGGCAGGTAGATGACGAGCATCAGGGACAGCTTCAAGGATCGCTCGCGGCTCTTACCAGCCTAAC
TTCGATCATTGGACCGCTGATCTTCACGGCGATTTATGCCGCCTCGGCGAGCACATGGAACGGGTTGGCATGGATTGTAG
GCGCCGCCCTATACCTTGTCTGCCTCCCCGCGTTGCGTCGCGGTGCATGGAGCCGGGCCACCTCGACCTGA

Protein sequence :
MKSNNALIVILATVTLDAVGIGLVMPVLPGLLRDIVHSDSIASHYGVLLALYALMQFLCAPVLGALSDRFGRRPVLLASL
LGATIDYAIMATTPVLWILYAGRIVAGITGATGAVAGAYIADITDGEDRARHFGLMSACFGVGMVAGPVAGGLLGAISLH
APFLAAAVLNGLNLLLGCFLMQESHKGERRPMPLRAFNPVSSFRWARGMTIVAALMTVFFIMQLVGQVPAALWVIFGEDR
FRWSATMIGLSLAVFGILHALAQAFVTGPATKRFGEKQAIIAGMAADALGYVLLAFATRGWMAFPIMILLASSGIGMPAL
QAMLSRQVDDEHQGQLQGSLAALTSLTSIIGPLIFTAIYAASASTWNGLAWIVGAALYLVCLPALRRGAWSRATST

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 3e-124 80
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 3e-124 80
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 4e-124 80
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 3e-124 80
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 5e-124 80
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 4e-124 80
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 6e-91 61
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 6e-91 61
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 6e-91 61
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 6e-91 61
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 3e-93 60
tetA YP_005797160.1 tetracycline resistance protein, class G (TETA(G)) Not tested AbaR4e Protein 1e-66 49
tet(H) YP_005176248.1 tetracycline efflux protein, class H Not tested ICEPmu1 Protein 3e-64 49
tetB AEA34667.1 tetracycline resistance determinant Not tested Not named Protein 2e-67 48
tetA(B) AEZ06045.1 tetracycline efflux protein Not tested Tn6167 Protein 3e-67 48
tetA(B) AAL08445.1 tetracycline resistance protein TetA(B) Not tested SRL Protein 2e-67 48
BJAB07104_00277 YP_008207742.1 Permeases of the major facilitator superfamily Not tested AbaR25 Protein 5e-67 48
BJAB0868_00281 YP_008211607.1 Permeases of the major facilitator superfamily Not tested AbaR26 Protein 5e-67 48
tetA(B) AEQ20905.1 tetracycline resistance protein Not tested Tn6166 Protein 5e-67 48
ABZJ_00260 YP_005524216.1 Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) Not tested AbaR22 Protein 5e-67 48
tetA(B) AFH57202.1 tetracycline resistance protein Not tested AbaR4a Protein 3e-67 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA Y19114.gene.p01 Protein 1e-144 99
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA NC_011586.7045189.p0 Protein 1e-115 81
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA X75761.gene.p01 Protein 7e-124 80
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA NC_010410.6002597.p0 Protein 2e-124 80
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA CP001485.1.gene2821. Protein 2e-124 80
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AF534183.gene.p01 Protein 7e-125 79
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA NC_010410.6002612.p0 Protein 2e-93 60
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AF133140.gene.p01 Protein 2e-93 60
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AF133139.gene.p01 Protein 1e-94 59
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AY264780.2.gene3.p01 Protein 6e-77 54
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AF070999.gene.p01 Protein 2e-81 54
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA Y19116.gene.p01 Protein 1e-72 53
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA L06940.gene.p01 Protein 6e-74 53
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AY743590.gene.p01 Protein 3e-70 50
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA Y15510.gene.p01 Protein 4e-65 50
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AJ420072.gene.p01 Protein 3e-63 49
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AF121000.gene.p01 Protein 4e-64 48
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA V00611.gene.p01 Protein 4e-67 48
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA NC_010558.1.6275971. Protein 1e-67 48
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA CP004022.1.gene2534. Protein 3e-66 48
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AF038993.gene.p01 Protein 2e-66 48
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AF090987.gene.p01 Protein 2e-63 48
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA L06798.gene.p01 Protein 2e-62 47
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AB084246.gene.p01 Protein 1e-67 47
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA AJ250203.gene.p01 Protein 2e-57 45
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA NC_011586.7043399.p0 Protein 1e-49 44
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA NC_011595.7059241.p0 Protein 3e-49 44
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA NC_010410.6003291.p0 Protein 2e-49 44
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA NC_009085.4918440.p0 Protein 4e-45 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CTRC122_04035 YP_008348545.1 tetracycline resistance structural protein TetA VFG1036 Protein 1e-67 48