Gene Information

Name : glnA (N220_12985)
Accession : YP_008339996.1
Strain : Mannheimia haemolytica USMARC_2286
Genome accession: NC_021883
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.1.2
Position : 2462877 - 2464298 bp
Length : 1422 bp
Strand : +
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGTCAAACGCAATCGCTAATGTATCTAAACTGATTCAAGACAATGATATTAAATTTGTCTTATTAAAATTTACTGATAT
TAAAGGTAAAGAACACGGGGTTTCGCTCCCTGTCAGCTTAGTTGCCAACGATTTGGAAGACTTATTCGAGGAAGGCAAAA
TGTTCGACGGTTCGTCCGTAGAAGGTTGGAAGGCAATTAACAAAGCAGATATGTTGTTAATGCCGATTGCTGAAACCGCT
GTAGTTGACCCTTTCGCCCGTATTCCTACCCTTTCTATTCGTTGTTCCATTTACGACCCAAACACAATGCAGTCTTATGA
CCGTGACCCTCGCTCTATTGCAACCCGTGCCGAAAACTACTTGAAATCCACCGGTATCGCCGATAGCGTAATGTTTGGAC
CTGAGCCTGAATTTTTCTTATTCGATGATGTGCGTTTTAGCACCGAAATGAACAATGTGTCATACCGAATTGACGATGTA
GAAGCGGCTTGGAATACCAACCGTAAATTTGAAGAAGGCAACAAAGCCTATCGTCCGTTGAAAAAAGGCGGCTACTGTGC
GGTTGCACCGATTGATACCGCCCACGATATTCGCTCCGAAATGTGTTTATTGATGGAAGAGATGGGTTTAGTGATTGAAG
CTCACCACCACGAAGTTGCGACAGCCGGACAAAATGAGATCGCAACCCGATTCAACAGCCTGACCTTAAAAGCCGATGAA
ACCCAAATCTATAAATACATCGTGCAAAATGTTGCCGTAGAACACGGAAAAACCGCTTGCTTTATGCCAAAACCGTTCGC
CGGCGACAACGGCTCGGGAATGCACTGTAATATGTCATTAAGCAAAGACGGCAAAAATGTGTTTATGGGCGATAAATACG
CCGGCTTATCTGAAACTGCCCTCTACTATATTGGCGGTATCATTAAACACGCAAAAGCATTAAATGCCTTTACTAACCCA
ACCACGAACTCTTATAAACGTTTAGTGCCGGGTTTTGAAGCACCGGTGTTATTGGCATATTCTGCAAGTAACCGCTCTGC
CTCTATCCGTATTCCGGCTGTGACCAGTCCGAAAGCGACCCGTGTAGAAGCACGCTTCCCGGATCCAATGGCAAACCCAT
ACCTTTGCTTTGCCGCCCTGTTAATGGCTGGCTTAGACGGTGTGATCAACAAAATCCACCCGGGCGATGCAATGGATAAA
AACTTATACGATTTACCGCCGGAAGAGTTAAAAGATATTCCAACGGTTGCCTCGTCTTTAGAACCCGCTCTTGACGCATT
AAGCAATGATTTTGAATTCTTAACACAAGGTGGCGTGTTCACGAAAGACTTTATTGATGCTTATATCGGTATTCGTCGCA
AAGAGGTGGAACGTGTAAATATGACTCCGCACCCGGTAGAATTTGAACTTTACTATTCATAG

Protein sequence :
MSNAIANVSKLIQDNDIKFVLLKFTDIKGKEHGVSLPVSLVANDLEDLFEEGKMFDGSSVEGWKAINKADMLLMPIAETA
VVDPFARIPTLSIRCSIYDPNTMQSYDRDPRSIATRAENYLKSTGIADSVMFGPEPEFFLFDDVRFSTEMNNVSYRIDDV
EAAWNTNRKFEEGNKAYRPLKKGGYCAVAPIDTAHDIRSEMCLLMEEMGLVIEAHHHEVATAGQNEIATRFNSLTLKADE
TQIYKYIVQNVAVEHGKTACFMPKPFAGDNGSGMHCNMSLSKDGKNVFMGDKYAGLSETALYYIGGIIKHAKALNAFTNP
TTNSYKRLVPGFEAPVLLAYSASNRSASIRIPAVTSPKATRVEARFPDPMANPYLCFAALLMAGLDGVINKIHPGDAMDK
NLYDLPPEELKDIPTVASSLEPALDALSNDFEFLTQGGVFTKDFIDAYIGIRRKEVERVNMTPHPVEFELYYS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 4e-92 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_008339996.1 glutamine synthetase VFG1399 Protein 7e-105 50