Gene Information

Name : leuS (N220_05155)
Accession : YP_008338489.1
Strain : Mannheimia haemolytica USMARC_2286
Genome accession: NC_021883
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.4
Position : 1003790 - 1006375 bp
Length : 2586 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAACAGCAGTATAACCCAAGTGAGATTGAACCTAAGGTTCAGCGTTATTGGGCAGAAAATAAAGTTTTTAAAGCAGT
TAAAGACGTTACCAAAGAGAAATACTATTGCCTTTCAATGTTGCCTTATCCGTCAGGTAAGCTACATATGGGGCACGTTC
GTAACTACACCATTGGTGATGTAGTGTCTCGTTATCAGCGTATGATCGGTAAAAATGTATTACAGCCGATGGGTTGGGAC
GCTTTCGGTTTACCGGCGGAAGGTGCTGCGGTGAAAAATAATACCGCACCGGCAAAATGGACTTACGAAAACATCGAATA
TATGAAAGGTCAGCTTAAAATGTTGGGCTTCTCTTATGACTGGGATCGTGAAGTCACCACTTGCCGTCCGGAATACTACA
AATGGGAGCAATGGTTCTTCACAGAACTTTATAAAAAAGGCTTAGTGTATAAAAAAACCTCAACCGTAAACTGGTGTCCG
AATGATGAAACTGTGCTTGCCAACGAGCAAGTTCACGAAGGTTGTTGCTGGCGTTGTGACACCCCAGTGGAACAGCGTGA
AATTCCACAATGGTTTATCAAAATCACTGACTATGCTGAAGAATTACTCAATCAGTTAGATAATCTCCCACAGTGGCCGG
ATCAAGTAAAAACCATGCAACGCAACTGGATCGGTCGTTCCGAAGGGGTAGAAATCACCTTTAAAATTGCCGGTTCAAAC
GTAGAATTACCGGTTTACACTACCCGTCCGGATACCTTCTTCGGCGTAAGCTATGTGGCGATTGCTGCGGCTCACCCATT
AGCAGAATTAGCTGCACAAAATAACCCGGCATTGGCTGAATTTATCCGTGAAGCGAAAAACACCAAAGTGGCAGAAGCAG
AATTAGCCACCATGGAGAAAAAAGGAATGGCAACCGGCTTGTTCGCCATTCACCCGTTAACAGGAAAAGAAGTACCGGTT
TGGGTTGCTAACTTTGTGTTAATGCACTACGGTACAGGTGCGGTAATGGCGGTTCCGGCTCACGATGAGCGTGACTTTGA
ATTTGCACAAAAATACGATTTGCAAATTAATCAGGTAATTCAACCGCTTGATGGCTCAGAGTGGGATTTCAGCAAAGCCG
CTTACACCGAACACGGTAAATTAATCAACTCTGCCGAGTTTGACGGCTTGGAATTTGATGTGGCTTTCACTGCGATTGCC
GATAAATTAGAGGCAATGGGTGTAGGTAAACGCCAAGTGAATTTCCGTCTGCGTGACTGGGGTGTTTCTCGTCAACGTTA
TTGGGGTGCACCAATCCCAATGATGACCACAGAAGAGGGCGAAGTGGTTACCGTTCCATTACAAGATTTACCGGTGATTC
TCCCTGAAGATGTGGTAATGAACGGCGTGCAAAGCCCAATCAAAGCCGACCCAGAGTGGGCGAAAACCACTTACAACGGC
AAACCGGCATTGCGTGAAACCGATACCTTCGATACCTTTATGGAGTCCTCTTGGTATTATGCACGTTATACTTGCCCACA
ATATCACGAAGGAATGTTAGATTCAGACGAGGCAAACTACTGGCTACCGGTCGATCAATATATCGGCGGTATTGAACACG
CCACAATGCACTTGCTCTACTTCCGTTTCTTCCATAAATTGTTGCGTGATGCGGGTATTTTAAATTCGGACGAACCGGCG
ACTAAACTGTTATGCCAAGGTATGGTGCTTGCCGATGCGTTCTACTACACCAGCCCAACTAACGAGCGTATTTGGGTCAG
CCCGACACAAGTCACCTTAGAACGTGATGAGAAAGGTCGTATCATCAAAGCAACCGATCCACAAGGGCGTGAGCTGGTTC
ACAGCGGTATGACTAAAATGTCGAAATCAAAGAACAACGGTATCGATCCGCAAGAAATGGTGGAAAAATATGGTGCTGAC
ACAGTTCGCTTGTTTATGATGTTTGCCTCCCCTGCGGAAATGACATTAGAATGGCAAGAATCCGGCGTTGAAGGGGCAAA
ACGTTTCTTAGGTCGTGTTTGGAATTTAGTTTATAGCTATGCCCAAAATCCGGCAACGACTGCATTAGATGTGAATGCCT
TAGACAAGGATCAAAAAGAACTTCGCCGTGATGTACACAAAACGATTGCTAAGGTGAGTGATGATATTGGTCGTCGTCAA
ACCTTCAATACAGCGATTGCTGCGGTGATGGAATTGATGAACAAGCTCACCAAAGCCCCACTTGAAACCGAACAAGATAA
AGCCGTAATGGCAGAAGCTTTAAGTGCGGTGGTGCGTATGCTTTACCCAATCACGCCACATATCTGCTTTGAGTTATGGC
AAGTGTTAGGTAATGAACAAACCATCGATTTTGCCCCTTGGGTACAAGCCGATGAATCCGCAATGGTGGAAGATGAAAAA
TTAGTGGTAGTACAAGTCAACGGAAAAGTGCGTGGCAAAATCACTGTTTCAGCTACTGCTACGGAAGATGAAGTTAAAGC
TATCGCTAAAGCCGATCCAAACGTTGCTAAATTCTTAGATGGTCAGCAGATTGTAAAAGAAATCTACGTTCCATTTAAAA
TGTTGAGCTTTGCGGTTAAGGCGTAA

Protein sequence :
MQQQYNPSEIEPKVQRYWAENKVFKAVKDVTKEKYYCLSMLPYPSGKLHMGHVRNYTIGDVVSRYQRMIGKNVLQPMGWD
AFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDREVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP
NDETVLANEQVHEGCCWRCDTPVEQREIPQWFIKITDYAEELLNQLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSN
VELPVYTTRPDTFFGVSYVAIAAAHPLAELAAQNNPALAEFIREAKNTKVAEAELATMEKKGMATGLFAIHPLTGKEVPV
WVANFVLMHYGTGAVMAVPAHDERDFEFAQKYDLQINQVIQPLDGSEWDFSKAAYTEHGKLINSAEFDGLEFDVAFTAIA
DKLEAMGVGKRQVNFRLRDWGVSRQRYWGAPIPMMTTEEGEVVTVPLQDLPVILPEDVVMNGVQSPIKADPEWAKTTYNG
KPALRETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGILNSDEPA
TKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLERDEKGRIIKATDPQGRELVHSGMTKMSKSKNNGIDPQEMVEKYGAD
TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYSYAQNPATTALDVNALDKDQKELRRDVHKTIAKVSDDIGRRQ
TFNTAIAAVMELMNKLTKAPLETEQDKAVMAEALSAVVRMLYPITPHICFELWQVLGNEQTIDFAPWVQADESAMVEDEK
LVVVQVNGKVRGKITVSATATEDEVKAIAKADPNVAKFLDGQQIVKEIYVPFKMLSFAVKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-156 42