Gene Information

Name : glnA (K748_07870)
Accession : YP_008337428.1
Strain : Helicobacter pylori UM298
Genome accession: NC_021882
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.1.2
Position : 1540334 - 1541779 bp
Length : 1446 bp
Strand : -
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGGTAGTAAGAACTCAAAATAGTGAAAGCAAAATCAAAGAATTTTTTGAATTTTGCAAAGAAAATGAAGTGGAATTTGT
GGATTTTAGATTCAGCGATATTAAAGGCACTTGGAATCATATCGCTTATTCTTTTGGGGCTTTAACGCATGGCATGTTTA
AAGAGGGGATTCCTTTTGATGCGAGTTCTTTTAAGGGATGGCAAGGCATTGAACACTCCGATATGATTTTAACCCCCGAT
TTGGTGCGTTATTTCATTGACCCTTTTAGCGCGGATGTGAGCGTAGTCGTGTTTTGCGATGTGTATGATGTGTATAAAAA
CCAGCCTTATGAGAAATGCCCTAGAAGTATCGCTAAAAAAGCCTTACAACATTTAAAAGATTCAGGTTTGGGCGATGTGG
CTTATTTTGGTGCAGAGAATGAATTTTTCATCTTTGATTCCATTAAAATTAAAGACGCTTCCAATTCCCAATACTATGAA
GTGGATAGCGAAGAGGGCGAATGGAATAGGGATAGAAGTTTTGAAAATGGCGTGAATTTTGGGCATAGACCGGGCAAGCA
AGGGGGCTATATGCCTGTGCCACCAACGGATACGATGATGGATATTCGCACAGAAATTGTGAAAGTCTTAAACCAAGTGG
GGTTAGAAACTTTTGTCGTCCATCATGAAGTCGCACAAGCGCAAGGCGAAGTGGGCGTAAAATTTGGGGATTTAGTGGAA
GCCGCTGACAATGTCCAAAAACTCAAATATGTGGTTAAAATGGTCGCTCATTTAAACGGCAAAACCGCCACTTTCATGCC
AAAACCTTTATATGGGGATAACGGGAGCGGGATGCACACCCATGTGAGTGTTTGGAAAAACAACGAAAACCTTTTTAGCG
GCGAAACTTACAAGGGCTTGAGCGAGTTGGCGTTGCATTTTTTAGGGGGCGTGTTGCGTCACGCTAGAGGGTTAGCCGCT
TTCACTAACGCTTCCACTAATTCTTACAAACGCCTGATTCCTGGCTATGAAGCCCCATCTATTTTAACCTATTCGGCTAA
CAACAGGAGTGCGAGCGTGCGTATCCCTTATGGGATTTCTAAAAACAGCGCGAGGTTTGAATTCAGGTTTCCTGATAGCT
CATCAAACCCCTACTTGGCTTTTGCAGCGATTTTAATGGCAGGCATGGATGGCGTTAAAAACAAGATTGATCCTGGCGAA
GCGATGGACATTAACCTTTTCAAATTGACTTTAGATGAAATCAGAGAAAAGGGTATCAAGCAAATGCCCCACACCTTAAG
GAGATCGCTAGAAGAAATGCTAGCCGATAAGCAGTATTTAAAAGAAGGTCAGGTCTTTAGCGAAGAATTTATTCAAGCCT
ATCAGTCTCTTAAATTCAACGCTGAAGTGTTCCCATGGGAGAGCAAACCCCATCCTTTTGAATTTATCACCACTTATTCA
TGCTAA

Protein sequence :
MVVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFDASSFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDRSFENGVNFGHRPGKQGGYMPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNVQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGLSELALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFAAILMAGMDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRRSLEEMLADKQYLKEGQVFSEEFIQAYQSLKFNAEVFPWESKPHPFEFITTYS
C

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_008337428.1 glutamine synthetase VFG1399 Protein 1e-89 45