Gene Information

Name : glnA (YYY_05830)
Accession : YP_008335784.1
Strain : Anaplasma phagocytophilum Dog2
Genome accession: NC_021881
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.1.2
Position : 1319528 - 1320946 bp
Length : 1419 bp
Strand : +
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGTTCCTATTCACAAAAGACTTGCTGGACTATGTAGAAAAGCACGGAATAAAATTCATAGATTGGCGGTTCACTGACTT
GCTAGGAAGGTGGTATCATATCACTCATAGCACCAATTTCTTAGATCCAGGAGTTTTCACATCTGGTGTTGCTTTTGACA
GTTCTTCAGTTCCAGGATGGCAGCCCATCGAGGCGTCTGATATGCTTCTGGTGCCTGATATAAGCACTGCGTTTGTAGAT
CCTTTCTCTGCGCAGGCGACGTTGTCTGTAATCTGTAATGTTGTTTGTCCTGGTGACCGGACTGACTATTCACGTGATCC
AAGGTATACGGCACGTAAGGCTCATCACTACCTGGTGTCAAAGTCCATCGCTGACAAGTGCTTTTTTGGGCCCGAAGTTG
AGTTTTTTGTTTTTGATCGTGTGCGCTTTGCAGCAGAGTCACATAATTCGTTTTTCAAATTAACATCGGTAGAGAGCTCA
TCTGGAGCGTCGAAGAGGTTTGACTCAAGTCATGGATATGGCTTAAAGGAAAGAGGTGGTTATCTCTGTTCTTCACCGAT
GGACTCTTCTCACGACATGCGTTCTGAAGTGCTTTCTATGCTAGATGAAGTAGGCGTTAAGCCGTTGCTTCACCATCATG
AAGTGGCTTCATCGCAGTGTGAAGTTGGGTTCCATCATAACGAGTTAGTTGCTGCTGCGGATAGTGTGCAGAAGTGTAAG
TATGTGCTTAGAAATGTGGTGGGCTCATACGGAAAAAGCGTCACTTTCATGCCTAAGCCGGTGGTTGGTGATAACGGTAG
CGGTATGCATTGCCATCAATCATTATGGAAGGATGGTAATAACATATTTGCCGGTGATAACGGTACAGCTGGGCTTTCAG
ATACGTGTCTTTACTATATTGGGGGTATTCTTGCCCATGGAAAGGCGCTGAATGCTTTTGCTAATCCGTCTACTAACAGT
TACAAGCGTCTTGTGCCGAATTTTGAGGCTCCAACGTGGCTTGCGTATTCTCATGGAAATCGTTCGGCAGCTGTACGGGT
GCCTTTTGTGCCGAGTAATAGTGTTGCAGCGCGTCGTATAGAAGTGAGATTTCCGGATCCGTTGGCGAATCCATACTTGT
GTTTTGCATCGCAGCTGATGGCTGGGTTGGATGGTATAAAGAACAAGATTATGCCGCCAGAGGTGCAGGGTAGGTCATTA
TATGACATGAGTGAGGACGAAGTTCGAGGTTTGTCATCAGTTTGTTTCTCGCTGGAAGAGGCTTTAGAAGCTCTAGACAA
GGACAGAGGGTTTCTTGTAGAAGGTGGTGTTTTCACTAATGACCAAATAGATGCTTATATCAAGCTGAAGAGGCAGGAAG
CTCATGAGTTACGTATTCATCCGCATCCAGTGGAGTTTTCTAATTATTACGCGTTATAG

Protein sequence :
MFLFTKDLLDYVEKHGIKFIDWRFTDLLGRWYHITHSTNFLDPGVFTSGVAFDSSSVPGWQPIEASDMLLVPDISTAFVD
PFSAQATLSVICNVVCPGDRTDYSRDPRYTARKAHHYLVSKSIADKCFFGPEVEFFVFDRVRFAAESHNSFFKLTSVESS
SGASKRFDSSHGYGLKERGGYLCSSPMDSSHDMRSEVLSMLDEVGVKPLLHHHEVASSQCEVGFHHNELVAAADSVQKCK
YVLRNVVGSYGKSVTFMPKPVVGDNGSGMHCHQSLWKDGNNIFAGDNGTAGLSDTCLYYIGGILAHGKALNAFANPSTNS
YKRLVPNFEAPTWLAYSHGNRSAAVRVPFVPSNSVAARRIEVRFPDPLANPYLCFASQLMAGLDGIKNKIMPPEVQGRSL
YDMSEDEVRGLSSVCFSLEEALEALDKDRGFLVEGGVFTNDQIDAYIKLKRQEAHELRIHPHPVEFSNYYAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 1e-85 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_008335784.1 glutamine synthetase VFG1399 Protein 2e-85 46