Gene Information

Name : guaA (A7H1H_0932)
Accession : YP_008330866.1
Strain : Arcobacter butzleri 7h1h
Genome accession: NC_021878
Putative virulence/resistance : Unknown
Product : GMP synthase (glutamine-hydrolyzing)
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 889304 - 890839 bp
Length : 1536 bp
Strand : -
Note : bifunctional; Pfam matches to PF00117.23 GATase, and to PF00958.17 GMP_synt_C, and to PF02540.12 NAD_synthase

DNA sequence :
ATGAAACATGTACCAATAGTAGTTTTAGATTTCGGTAGTCAATATACTCAAATCATTGCTAGAAAACTTAGAGAAGCAGG
TGTTTACTCTGAAATAGTTCCTTATAATGAACCTATTGGAGATATAGTAGCTAGAACTCCAAAAGGAATTATTCTATCAG
GTGGACCAGCATCTGTTTATGCTGTTGATGCTTATCATCCAGATACTACAATATTTGAATTGGGTCTTCCAATTTTAGGT
ATTTGTTATGGAATGCAACTAATCTCTCAACACTTTGGTGGAAGTGTAATTCCAGCAAGCCACCACGAATATGGAAAAGC
TAAATTACAATTTGAAGTTGAAAATCCAATTTTCAAAGATACACAAGATGGTCAAATTGTTTGGATGAGCCACGGAGATA
GAGTTGAAAATATCCCTGCTGGATTTGAAAAAATCGCAACAAGTGAAAATTCTCCATATGCAGCTATTGCAGATATAAAT
AGAAATATTTATGCGTTCCAATTTCACCCAGAAGTTTATCACTCACAAGAAGGAAGCAAACTTCTTAAAAACTTTGCTAA
ACATATTTGTGGTTGTGAATCTACTTGGAATATGGGAAGTTTTGCAAAAGAACAAATAAAACAAATCCAAGATAAAGTTG
GAAATAAAAAAGTATTATGTGCAGTTTCAGGTGGAGTTGATAGCTCAGTTGTAGCAACTTTATTAGCTGAAGCTATTGGA
GAGCAAGTAATTCCTGTATTTGTAGACAATGGACTTTTAAGAGCAAATGAAAGAGAACAAGTTGAAACTATGTTCAAAAG
CAGAGGTGTAAATCTAATCACTGTTGATGCAAGTGAAACTTTCTTATCAAAACTAGCTGGTGTTACGGACCCAGAGAAAA
AAAGAAAAATCATTGGTGAAACATTTATCGAAGTATTTGATGTAGAAGCAAAAAAACACTCTGGAATTGAGTTTTTAGCA
CAAGGAACTTTATATACAGATGTTATCGAATCAGTTTCTGTAAAAGGTCCAAGTAAAACTATCAAATCTCACCACAATGT
TGGTGGTCTTCCTGATTGGATGAAATTTGAACTAATTGAGCCTCTAAGAGAGATTTTTAAAGATGAAGTTAGAGCTTTAG
GATTAGAACTTGGTCTTCCAAAAAGTATGATAAGCAGACATCCATTCCCTGGTCCTGGTCTTGCTATTAGAATTATGGGT
GAAGTAAATAAACCTGATTTAGAACTTTTAAGAAAAGCTGATGTTATCATGCTTGATGTATTACATTCAACTGGATATTA
TGATAAAACTTGGCAAGCATTTACAGTATTATTAAATGTAAAATCTGTTGGTGTTATGGGTGATAATAGAACTTATGATA
ACACAGTTTGTGTAAGAATAGTAGATGCAACAGATGGTATGACAGCAACTTTTGCACATATTCCACATGAAATACTTGAA
ACTATCTCAAGAAGAATTATCAACGAAGTTGATGGAATCAATAGAGTAGTTTATGATATTTCATCAAAACCCCCAGCAAC
TATCGAGTGGGAATAA

Protein sequence :
MKHVPIVVLDFGSQYTQIIARKLREAGVYSEIVPYNEPIGDIVARTPKGIILSGGPASVYAVDAYHPDTTIFELGLPILG
ICYGMQLISQHFGGSVIPASHHEYGKAKLQFEVENPIFKDTQDGQIVWMSHGDRVENIPAGFEKIATSENSPYAAIADIN
RNIYAFQFHPEVYHSQEGSKLLKNFAKHICGCESTWNMGSFAKEQIKQIQDKVGNKKVLCAVSGGVDSSVVATLLAEAIG
EQVIPVFVDNGLLRANEREQVETMFKSRGVNLITVDASETFLSKLAGVTDPEKKRKIIGETFIEVFDVEAKKHSGIEFLA
QGTLYTDVIESVSVKGPSKTIKSHHNVGGLPDWMKFELIEPLREIFKDEVRALGLELGLPKSMISRHPFPGPGLAIRIMG
EVNKPDLELLRKADVIMLDVLHSTGYYDKTWQAFTVLLNVKSVGVMGDNRTYDNTVCVRIVDATDGMTATFAHIPHEILE
TISRRIINEVDGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-134 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-135 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-135 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-116 50