Gene Information

Name : lysS (N134_01395)
Accession : YP_008325631.1
Strain : Lactobacillus reuteri TD1
Genome accession: NC_021872
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 342830 - 344347 bp
Length : 1518 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGTCACAAGAACTAGATCAAATGCGCGTTCGGCGTGAAAAAATGGAAGAGTTAAAAGAAGCGGGGATTGAACCATTTGG
CCGCCGCTTCAAACGAGACCATCTTGCCCAAGACTTGCATGATAAGTTTGATCAATACGATAAAGAAGAATTAAACGAGA
TGGGCGCCAAAGTAATTATTGCGGGTCGAATGACAAGAAAGCGGAGTAGTGGTAAGGCTGGGTTCGCTGACTTTGTTGAT
CGGACTGGTAAGATTCAAGTTTACGCTCGTAAGGATATGGTCGGGGATGAGCCTTACCATGTTTTCAAGCGGTCAGATAT
TGGTGACTTCCTTGGAATTGAAGGGGATGTTATCAAGACAGATACAGGTGAATTAACTGTTCGTGCACATAAAATTACCT
TCTTGTCAAAAGCATTGCGTCCGCTTCCTAATAAGTGGGATGGGGTTACTGATCCTGAAACTATCTATCGTCAGCGCTAC
CTTGATTTAATTTCTAACCCAGAAAGCTTCAAGCGTTTCCACCAACGGACAGCGATCATCAAGGCCGTCCGGAAGTACAT
GGATGATAATGGCTTTACAGAGGTTGAAACTCCAATTTTGAACACCCAAGCTGGTGGTGCTAATGCGCGGCCATTTATCA
CTCACCATAATGCGCTTGATATTGATATGTACTTGCGGATTGCTACCGAATTGTACCTTAAGCGGTTAATCGTTGGTGGC
TTTGAACGGGTATACGAATTGGGCCGGATTTTCCGGAATGAAGGGATGGACCCTCACCATAACCCTGAATTTACGACAAT
GGAAACTTATGCTGCTTACTTTGACTTCCAAGATGTTATGGATGAAACAGAAGGAATCGTTAAGGCAGCAGCTAAAGTTG
TTTCAGATGATGGAAAGATTACTTACCAAGGACGTGAAATCGACCTTGGAGGAAACTTTAAACGGATTACGATGGTAGAT
GCCGTTAAGGAAAAGACTGGCATTAACTTTAGCGATGAATCAATGACGGACGAAGATGCTAAGAAGTTAGCCGATGAACA
TAAGGTTGAATATAAGCCTTACTGGACAAAGGGCCATATCTTGAATGCATTCTTTGAAGAGTTCGTTGAAGATACACTGA
TTCAACCAACTTTTGTCTATGAATTCCCAGTCGAAGTTTCACCATTAGCAAAGCGGAATGCTGATAATCCTGCGATGACT
GATCGTTTCGAATTGTATGTTGATGGTAGCGAATTGGCAAATGCCTTTAGTGAATTAAACGATCCAATTGATCAGAAGGA
ACGTTTTGAAATGCAAGCAAAGGAAAAAGCTAATGGTAATGATGAAGCTGAACCAGTCGACTTAGATTACGTTCAAGCCC
TCGAATACGGGATGCCACCTACTGGGGGACTTGGTATTGGAATCGACCGTCTTGTAATGCTCCTTACTGATGCTAAATCT
ATTCGGGATGTTATTCTCTTCCCAACAATGCGTCCAGAAAAGGAAGCTAAGAACGATTCAAAGAAAAAGAAGAAGTAA

Protein sequence :
MSQELDQMRVRREKMEELKEAGIEPFGRRFKRDHLAQDLHDKFDQYDKEELNEMGAKVIIAGRMTRKRSSGKAGFADFVD
RTGKIQVYARKDMVGDEPYHVFKRSDIGDFLGIEGDVIKTDTGELTVRAHKITFLSKALRPLPNKWDGVTDPETIYRQRY
LDLISNPESFKRFHQRTAIIKAVRKYMDDNGFTEVETPILNTQAGGANARPFITHHNALDIDMYLRIATELYLKRLIVGG
FERVYELGRIFRNEGMDPHHNPEFTTMETYAAYFDFQDVMDETEGIVKAAAKVVSDDGKITYQGREIDLGGNFKRITMVD
AVKEKTGINFSDESMTDEDAKKLADEHKVEYKPYWTKGHILNAFFEEFVEDTLIQPTFVYEFPVEVSPLAKRNADNPAMT
DRFELYVDGSELANAFSELNDPIDQKERFEMQAKEKANGNDEAEPVDLDYVQALEYGMPPTGGLGIGIDRLVMLLTDAKS
IRDVILFPTMRPEKEAKNDSKKKKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-113 47
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-84 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_008325631.1 lysyl-tRNA synthetase VFG1668 Protein 7e-114 47