Gene Information

Name : M636_22130 (M636_22130)
Accession : YP_008317711.1
Strain :
Genome accession: NC_021848
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2979079 - 2981019 bp
Length : 1941 bp
Strand : +
Note : catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Hom

DNA sequence :
ATGTCGAGTCGCAAACAAGCGAGACTGGAAGCAAAACAGTTTATTGATACTCTCTCGGTACAGCCGTACCCAAACTCAAC
CAAAGTGTATGTAGAGGGTTCTCGTCCTGACATCCGAGTGCCAATGCGTGAAATTTCTTTGGCTGATAGCCTAATTGGTG
GCACCAAAGAGGCTCCTGTTTTCGAGTCAAACGAATCAGTACGTGTTTATGACACCTCTGGTGTATACACTGACCCAAAT
CACTCTATCGACCTTTACAATGGCTTACCAAAGCTTAGAGAAGGGTGGATTGAAGAACGCAATGATACTGAAATCCTTGA
AGATGTGAGCTCTGTTTACGCAAAAGAGCGTCTTGACGATGAAACCTTAGATGATTTGCGTTATGGCAACTTACCACGTA
TTCGACGAGCTAAAGCCGGAAAATGTGTCACTCAACTACACTATGCTCGTAAAGGCATTGTTACTCCGGAAATGGAATAC
ATTGCACTGCGTGAGAACATGGGTCGCGCTAAATATCGCGATGACGTGCTGACTCAGCAGCATCCTGGTCAAAGCTTCGG
TGCAAATCTACCTAAAGACATTACTGCAGAATTCGTTCGTAAAGAAGTTGCAGAAGGTCGCGCCATCATTCCTTCGAATA
TCAATCATCCAGAATCTGAACCAATGATTATTGGCCGTAACTTCTTAGTTAAGGTGAATGCCAATATTGGTAACTCATCG
GTCACGTCTTCAATCGAAGAAGAAGTGGAGAAACTTGTCTGGGCGACACGCTGGGGTGGCGATACCGTGATGGACCTTTC
TACCGGCCGCAACATTCACGAAACTCGCGAATGGATTTTACGCAATAGCCCGGTGCCAATTGGTACGGTTCCTATGTATC
AGGCTTTGGAGAAAGTAAATGGCATTGCTGAGAACCTGAATTGGGAAGTCATGCGTGACACGTTAATCGAACAAGCAGAG
CAGGGCGTTGATTACTTTACTATCCATGCGGGTTTACTACTTCGCTATGTTCCAATGACGGCGAAACGAGTGACGGGGAT
TGTTTCGCGTGGTGGCTCGATTATCGCTAAGTGGTGTCTAGCACATCACCAAGAAAGCTTCTTATACACTCATTTCCGCG
AGATCTGTGAAATTTGTGCGAAGTACGATGTCGCTCTATCTCTTGGTGATGGCTTGCGTCCTGGCTCGGTTGCAGACGCG
AACGATGAAGCGCAATTCGCAGAGCTGCGTACGCTCGGCGAGTTGACGAAAATCGCATGGGAATATGATGTGCAGGTCAT
CATTGAAGGCCCTGGCCATATTCCAATGCATATGATTAAAGAAAATATGGACCAACAGCTGGAACACTGTCATGAAGCGC
CATTCTACACCTTGGGTCCTCTAACGACAGATATCGCTCCGGGTTATGACCACATTACATCCGGTATAGGTGCGGCGATG
ATTGGTTGGTATGGCTGCGCTATGTTGTGCTACGTGACCCCTAAGGAGCACTTGGGGCTTCCAAATAAAGAAGACGTTAA
AACCGGTATGATCACCTACAAGTTAGCTGCGCATGCTGCGGATTTAGCAAAAGGGCATCCGGGAGCACAAGTTCGTGACA
ATGCTTTATCAAAGGCGCGTTTTGAATTCCGCTGGGAAGACCAATTTAACCTCGCTTTAGACCCCGATACCGCACGTGCA
TTTCATGATGAAACGCTGCCGCAAGAGTCTGGAAAAGTAGCGCACTTCTGCTCAATGTGCGGCCCTAAATTCTGCTCAAT
GAAGATTTCTCAAGAAGTCAGGGAGTATGCCAAAGATACAGAGCAAGTTGCCGCGGATCAGGCGATTTCTATCAAGATGT
TAGATGACCCGATGGAAGGCATGCGTAAGAAGTCTGAAGAGTTTCGTGCGACAGGTTCCGAGCTTTATCACCCAGCCGTG
CACGCCGAGGCGGATGAGTAA

Protein sequence :
MSSRKQARLEAKQFIDTLSVQPYPNSTKVYVEGSRPDIRVPMREISLADSLIGGTKEAPVFESNESVRVYDTSGVYTDPN
HSIDLYNGLPKLREGWIEERNDTEILEDVSSVYAKERLDDETLDDLRYGNLPRIRRAKAGKCVTQLHYARKGIVTPEMEY
IALRENMGRAKYRDDVLTQQHPGQSFGANLPKDITAEFVRKEVAEGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSS
VTSSIEEEVEKLVWATRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGIAENLNWEVMRDTLIEQAE
QGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSVADA
NDEAQFAELRTLGELTKIAWEYDVQVIIEGPGHIPMHMIKENMDQQLEHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAM
IGWYGCAMLCYVTPKEHLGLPNKEDVKTGMITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLALDPDTARA
FHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDTEQVAADQAISIKMLDDPMEGMRKKSEEFRATGSELYHPAV
HAEADE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 68