Gene Information

Name : guaA (M636_18740)
Accession : YP_008317061.1
Strain :
Genome accession: NC_021848
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 2259940 - 2261493 bp
Length : 1554 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGACTAAAAATATCCATGACCAACGTATTCTGATCTTGGACTTCGGTTCTCAGTACACTCAATTAGTTGCGCGTCGCGT
ACGTGAAATCGGCGTTTACTGTGAACTATGGAGCTGGGACGTAGAAGAAGCGGATATTCGCGAATTCAACCCAGATGGCA
TCATCCTTTCTGGTGGCCCAGAAAGCGTTACAGAAGAAAACTCTCCTCGCGCTCCTCAATATGTATTTGACTCAGGTGTT
CCTGTACTTGGTGTATGTTACGGCATGCAAACCATGGCAGAACAGCTAGGTGGTAAAGTAGCGGGCTCAAACGAGCGTGA
ATTTGGCTACGCACAAGTAAAAGTTTCTGGCGAATCTGCGATCTTCAAAGATCTTGAAGCGACTCAAGACGTTTGGATGA
GCCACGGCGACAAAGTTGTAGAAATTCCAGCAGACTTCGTAAAAGTCGGTGAGACAGACACTTGTCCTTACGCGGCAATG
GCGAACGAAGAGAAGAAATACTACGGCGTTCAGTTCCACCCAGAAGTAACACACACGAAAGGTGGCCTACAAATGCTAGA
GAACTTCGTTCTTGGCGTGTGTGGTTGTGAACGTCTATGGACATCAGAATCTATCATTGAAGACGCGGTTGCTCGCATTA
AAGAACAAGTGGGTGACGATGAAGTGATCCTAGGTCTATCTGGCGGTGTGGATTCATCCGTTGTTGCTATGCTGGTTCAC
CGTGCAATTGGCGACAAGCTTACATGTGTATTCGTGGATAACGGCCTGCTTCGTCTAAACGAAGGTCAGCAAGTAATGGA
TATGTTCGGCGATAAGTTCGGCCTAAACATCATCAAAGTTGACGCAGAAGAGCGTTTCCTTGAAGCGCTGAAAGGCAAGT
CTGACCCAGAAGAAAAACGTAAGACTATCGGTCACGTGTTCGTAGACGTATTCGATGAAGAATCGAAGAAGCTGAAAAAC
GCAAAATGGCTTGCTCAGGGTACTATCTACCCAGACGTAATCGAGTCTGCAGCATCTAAAACTGGTAAAGCGCACGTGAT
CAAATCACACCACAACGTGGGCGGTCTACCTGACGATATGGAAATGGGTCTAGTTGAGCCACTACGTGAGTTGTTCAAAG
ATGAAGTTCGTAAGATTGGTCTGGAGCTAGGTCTTCCGTACAACATGCTTTACCGTCACCCGTTCCCAGGTCCAGGTCTA
GGTGTTCGCGTTCTTGGCGAGATCAAGAAAGAATACTGTGACTTGCTACGTCGTGCTGACGCTATCTTTATTGAAGAGCT
TCACGCAGCAGACCTATACGACAAAGTATCTCAAGCGTTCACGGTATTCCTACCAGTTCGTTCTGTAGGCGTAATGGGCG
ACGGTCGTAAATACGATTGGGTGGTATCACTGCGTGCAGTTGAAACTATCGACTTTATGACAGCGCATTGGGCACACCTA
CCATACGACTTCCTAGGTAAGGTATCTAACCGTATTATCAACGAAGTTGAAGGTATTTCACGAGTTGTTTACGACATTTC
TGGTAAGCCACCAGCGACAATCGAGTGGGAATAA

Protein sequence :
MTKNIHDQRILILDFGSQYTQLVARRVREIGVYCELWSWDVEEADIREFNPDGIILSGGPESVTEENSPRAPQYVFDSGV
PVLGVCYGMQTMAEQLGGKVAGSNEREFGYAQVKVSGESAIFKDLEATQDVWMSHGDKVVEIPADFVKVGETDTCPYAAM
ANEEKKYYGVQFHPEVTHTKGGLQMLENFVLGVCGCERLWTSESIIEDAVARIKEQVGDDEVILGLSGGVDSSVVAMLVH
RAIGDKLTCVFVDNGLLRLNEGQQVMDMFGDKFGLNIIKVDAEERFLEALKGKSDPEEKRKTIGHVFVDVFDEESKKLKN
AKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGL
GVRVLGEIKKEYCDLLRRADAIFIEELHAADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHL
PYDFLGKVSNRIINEVEGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-134 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-134 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-134 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-113 49