Gene Information

Name : M636_16750 (M636_16750)
Accession : YP_008316693.1
Strain :
Genome accession: NC_021848
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.38
Position : 1845675 - 1846430 bp
Length : 756 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; Derived by automated computational analysis using gene prediction method:

DNA sequence : 
ATGTCTTTTACGGTTGTGATACCGGCTCGTTACTCTTCGAGCCGTTTACCAGGTAAACCACTGGCTGATATCGGTGGTAA
ACCAATGGTGCAATGGGTTTACGAACAAGCAATGCAAGCTGGCGCTGATGACGTGATCATTGCTACTGACGATGAGCGAG
TTTCTGCGGCGGTTGAGCAATTCGGTGGCAAAGTTTGTATGACTTCGCCAAACCACGAATCTGGTACAGAGCGTTTAGCG
GAAGTGGTAGAGAAAATGGCCATTCCTGCTGACCACATTATTGTGAACGTTCAAGGTGATGAGCCTTTGGTACCACCAGT
TATCATCCGCCAAGTCGCAGATAACTTAGCCGCTAGTGATGCGCCTATGGCTACGTTGGCGGTTGAAATTGAATCTGAAG
ATGAAGTCTTCAACCCAAATGCCGTAAAAGTCGTTGCTGATGAGCGTGGTTATGCCATGTACTTTAGCCGAGCAACAATT
CCTTGGGATCGTGATAACTTCGCTAAGCAAGACAAAGCTATCGTGAATCCATTGATGCGTCACATCGGTATCTATGCATA
CCGCGCAGGTTTCATTAATACTTACGTAAACTGGGCGCCAAGTGCCCTAGAGCAAATTGAATGCCTAGAGCAGTTACGAG
TGCTTTGGTACGGCGAGAAAATCCACGTTGCAGTCGCTAAAGAAGCGCCAGCAGCAGGCGTTGATACGCCAGAAGATCTT
GAAGCCGTTAGAGCTATTGTGGCGAAAAAAGCGTAA

Protein sequence : 
MSFTVVIPARYSSSRLPGKPLADIGGKPMVQWVYEQAMQAGADDVIIATDDERVSAAVEQFGGKVCMTSPNHESGTERLA
EVVEKMAIPADHIIVNVQGDEPLVPPVIIRQVADNLAASDAPMATLAVEIESEDEVFNPNAVKVVADERGYAMYFSRATI
PWDRDNFAKQDKAIVNPLMRHIGIYAYRAGFINTYVNWAPSALEQIECLEQLRVLWYGEKIHVAVAKEAPAAGVDTPEDL
EAVRAIVAKKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 5e-42 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 8e-42 45
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-41 45