Gene Information

Name : SEEB0189_21540 (SEEB0189_21540)
Accession : YP_008310575.1
Strain : Salmonella enterica CFSAN000189
Genome accession: NC_021844
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4444448 - 4446343 bp
Length : 1896 bp
Strand : +
Note : catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Hom

DNA sequence :
ATGTCTACAACAACGTTAACCCGCCGCGAGCAGCGCGCTAAAGCCCAGCATTTTATCGATACGCTGGAAGGCACCGCGTT
TCCCAACTCGAAACGCATCTACGTGACCGGTTCGCAGCATGATATTCGCGTACCGATGCGCGAAATTCAACTTAGCCCCA
CGCTCATCGGCGGCAGTAAAGACAACCCGCAGTTTGAAGAGAACGAAGCCGTACCGGTATACGACACCTCCGGCCCCTAT
GGCGATCCTGAGGTGGCGATTAACGTCCAGCAGGGTCTGGCGAAACTGCGCCAGCCATGGATTGACGCACGTAACGATAG
CGAAGAATTAGACGACCGTAGCTCGGCTTACACCAGAGAACGTCTGGCCGACGATGGCCTGGACGATCTGCGTTTTACCG
GCCTGCTGACGCCGAAACGCGCCAAAGTGGGCAAGCGCGTCACCCAGTTACACTACGCCCGCCAGGGGATCGTCACTCCC
GAAATGGAGTTCATCGCCATCCGTGAAAACATGGGCCGCGAACGCATTCGTAGTGAAGTGCTGCGCCACCAGCATCCGGG
CATGAACTTTGGCGCGCGCCTGCCGGAAAACATTACGCCGGAATTCGTGCGTGATGAAGTCGCCGCGGGCCGCGCGATTA
TTCCCGCCAACATCAACCACCCGGAATCCGAGCCGATGATTATCGGCCGCAACTTCCTGGTCAAAGTGAATGCCAACATC
GGCAACTCGGCGGTCACCTCCTCCATCGAAGAAGAGGTGGAAAAACTGGTCTGGTCGACCCGCTGGGGCGCGGACACGGT
AATGGACCTCTCCACCGGCCGCTATATTCACGAAACCCGCGAATGGATCCTGCGTAACAGCCCGGTACCGATCGGTACCG
TCCCGATCTACCAGGCGCTGGAGAAGGTCAACGGGATCGCCGAAGATCTCACCTGGGAAGCGTTCCGCGACACGCTGCTG
GAGCAGGCAGAACAGGGCGTCGACTACTTCACCATTCACGCCGGCGTGCTGCTGCGCTACGTGCCGATGACCGCCAAACG
CCTGACCGGCATTGTCTCACGCGGCGGTTCGATCATGGCGAAATGGTGCCTCTCGCATCACAAAGAGAACTTCCTGTTCG
AACATTTCCGCGAGATTTGTGAAATCTGCGCCGCCTACGACGTTTCCCTGTCGCTGGGCGACGGCCTGCGTCCCGGCTCC
ATTCAGGACGCCAACGACGAAGCGCAGTTCTCCGAGCTGCATACGCTGGGCGAGCTGACCAAAATCGCCTGGGAATACGA
CGTGCAGGTGATGATTGAAGGACCGGGACACGTGCCGATGCATATGATTCAGCGCAACATGACCGAAGAGCTGGAGAGCT
GCCACGAAGCGCCGTTCTACACTTTGGGGCCGTTGACCACCGACATCGCGCCGGGCTATGACCACTTCACCTCCGGCATT
GGTGCCGCGATGATCGGCTGGTTTGGCTGCGCGATGCTGTGTTATGTGACGCCGAAAGAACACCTCGGCCTGCCGAACAA
AGAAGATGTGAAGCAGGGGCTAATCACCTACAAAATCGCCGCCCACGCCGCGGATTTAGCCAAAGGACATCCGGGCGCGC
AGATCCGCGATAACGCCATGTCGAAAGCGCGCTTTGAATTCCGCTGGGAAGATCAGTTTAACCTCGCACTCGACCCGTTC
ACCGCCCGCGCTTATCACGATGAAACCCTGCCGCAGGAGTCCGGTAAGGTCGCTCACTTCTGTTCCATGTGCGGGCCGAA
GTTCTGCTCGATGAAAATCAGCCAAGAAGTACGTGACTACGCCGCCGCACAAACCATTGAAGTCGGCATGGCGGATATGT
CGGAGAACTTCCGCGCCAAAGGCGGCGAAATTTATCTCAAACGGGAGGAAGCCTGA

Protein sequence :
MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPY
GDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKVGKRVTQLHYARQGIVTP
EMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRAKGGEIYLKREEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 70