Gene Information

Name : SEEB0189_18135 (SEEB0189_18135)
Accession : YP_008309911.1
Strain : Salmonella enterica CFSAN000189
Genome accession: NC_021844
Putative virulence/resistance : Virulence
Product : lysine decarboxylase CadA
Function : -
COG functional category : -
COG ID : -
EC number : 4.1.1.18
Position : 3695595 - 3697736 bp
Length : 2142 bp
Strand : -
Note : constitutive; catalyzes the formation of cadaverine from lysine; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGAACATCATCGCCATTATGGGGCCGCACGGGGTTTATTATAAAGATGAACCCATCAAGGAGCTTGAGCGTGCATTACA
ATCCCTGGGATTTCAAATTATCTGGCCGCAAAATAGCGTTGACTTGTTGAAGTTTATTGAACATAACCCGCGCATCTGCG
GCGTTATTTTTGACTGGGATGAATACAGTCTCGACCTTTGTAGCGAAATCAACCAGCTAAATGAATACCTTCCTCTCTAC
GCCTTTATCAATACCAACTCCACGCTGGACGTTAGCGTTCACGATATGCGCATGGCGCTGTGGTTTTTTGAGTATGCATT
GGGGCTGGCTGAAGATATCGCGACGCGCATTCATCAATATACAAACGAATATCTCGATAATATTACGCCGCCGTTTACCA
AAGCGCTGTTTACCTACGCCAAAGAAGGAAAATATACCTTTTGTACGCCGGGTCATATGGCGGGAACGGCGTATCAGAAA
AGCCCGCCAGGCTGTCTGTTTTATGACTTTTTTGGCGGCAATACCTTAAAGGCCGATGTGTCGATTTCGGTGACTGAACT
GGGATCGCTGCTGGATCACACCGGGCCGCATCTGGAAGCGGAAGAGTATATCGCCCGTACTTTTGGCGCCGAGCAGAGTT
ATATGGTGACGAACGGTACGTCGACCTCGAATAAAATTGTCGGTATGTATGCCGCGCCTGCGGGAAGTACGCTACTTATT
GATCGCAATTGCCATAAATCGCTGGCGCATTTGCTGATGATGAGCGATGTGGTGCCTCTCTGGTTGAAGCCGACGCGCAA
TGCGCTCGGCATTCTCGGCGGTATTCCCCGAAGGGAATTTACCCGTGCAAGCATCGAAAGCAAGATAGAGGAGACCCCTC
AGGCGCAATGGCCGGTGCATGCGGTTATCACCAATTCGACTTACGATGGTCTGCTGTATAACACTAACTGGATCAAGCAA
ATGCTGGACGTTCCCTCGATCCATTTTGATTCCGCCTGGGTACCCTATACCCATTTCCATCCGATCTACCAGGGGAAAAG
CGGGATGAGCGGCGATCGGGTGCCCGGAAAAGTGATTTTCGAAACGCAATCCACCCATAAAATGCTGGCGGCTTTTTCGC
AGGCGTCGCTTATTCATATCAAAGGGGAATATGACGAAGAGACGTTTAACGAAGCGTTTATGATGCACACTTCCACATCG
CCGAGCTATCCCATTGTCGCCTCTATCGAGACCGCAGCGGCGATGCTGCGCGGCAATCCAGGGAAAAGATTGATTAATCG
TTCGGTGGAACGGGCGCTCCATTTTCGTAAAGAGGTACAGCGGCTACGTGAAGAGTCCGATAGCTGGTTCTTTGATATCT
GGCAGCCGGAAGAGGTTGATGAGGCCGAATGCTGGCCGGTCACGCCGGGAGAAACCTGGCATGGCTTCACCGATGCCGAT
GACGATCATATGTTCCTCGATCCGGTTAAGGTGACAATCCTGACGCCGGGGATGGATGAACAGGGCAACATGAGCGAAGA
GGGGATACCCGCCGCGCTGGTGGCGAAGTTCCTTGATGAGCGAGGCGTGGTGGTGGAAAAAACCGGGCCGTATAATCTGC
TGTTTTTGTTCAGCATAGGGATTGATAAGACCCGTGCGATGGGGCTGCTGCGCGGACTGACGGAATTTAAACGCGCCTAC
GATCTTAACCTGCGCGTCAAAAATATGTTGCCGGATCTGTATGCGGAAGATCCGGATTTTTATCGCAATATGCGCATTCA
GGATCTGGCGCAGGGGATCCATAAACTGATCCGCCAGCACGATCTTCCGGGGCTGATGCTGCGGGCGTTCGAGGTTTTAC
CGGAGATGATCATGACCCCGCACCAGGCCTGGCAGCGTCAGATCAAAGGTGAGGTGGAAACCGTGGCGCTCGATCAACTG
CCAGGGCGCGTTTCCGCGAATATGATCCTGCCTTATCCGCCAGGCGTTCCGCTGTTGATGCCCGGCGAGAGGATCACGCA
ACAGAGTCGGGCCGTGCTCGATTTTCTGCTGATGCTCTGCTCGATTGGCCAGCATTATCCCGGTTTTGAAACGGATATTC
ACGGCGCGAAACGGAATGAAGACGGGGTGTACCAGGTACGAGTCTTAAAACACGCCTGCTAG

Protein sequence :
MNIIAIMGPHGVYYKDEPIKELERALQSLGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSEINQLNEYLPLY
AFINTNSTLDVSVHDMRMALWFFEYALGLAEDIATRIHQYTNEYLDNITPPFTKALFTYAKEGKYTFCTPGHMAGTAYQK
SPPGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYMVTNGTSTSNKIVGMYAAPAGSTLLI
DRNCHKSLAHLLMMSDVVPLWLKPTRNALGILGGIPRREFTRASIESKIEETPQAQWPVHAVITNSTYDGLLYNTNWIKQ
MLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGDRVPGKVIFETQSTHKMLAAFSQASLIHIKGEYDEETFNEAFMMHTSTS
PSYPIVASIETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDSWFFDIWQPEEVDEAECWPVTPGETWHGFTDAD
DDHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGVVVEKTGPYNLLFLFSIGIDKTRAMGLLRGLTEFKRAY
DLNLRVKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRQHDLPGLMLRAFEVLPEMIMTPHQAWQRQIKGEVETVALDQL
PGRVSANMILPYPPGVPLLMPGERITQQSRAVLDFLLMLCSIGQHYPGFETDIHGAKRNEDGVYQVRVLKHAC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 71
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SEEB0189_18135 YP_008309911.1 lysine decarboxylase CadA VFG1670 Protein 0.0 62