Gene Information

Name : spiC (SEEB0189_12570)
Accession : YP_008308829.1
Strain : Salmonella enterica CFSAN000189
Genome accession: NC_021844
Putative virulence/resistance : Virulence
Product : pathogenicity island chaperone protein SpiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2549130 - 2549513 bp
Length : 384 bp
Strand : -
Note : involved in macrophage infection; inhibits phagosome-lysosome fusion and cellular trafficking; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence : 
ATGCTGGCAGTTTTAAAAGGCATTCCATTAATTCAGGATATCAGGGCCGAAGGTAATAGCCGATCCTGGATAATGACTAT
TGATGGGCATCCTGCCAGAGGAGAAATTTTCTCAGAAGCATTTTCTATTTCTTTGTTCTTAAATGACCTGGAAAGCTTAC
CTAAGCCTTGTCTTGCCTATGTGACACTACTGCTTGCAGCACACCCGGACGTCCATGATTATGCTATACAGCTCACAGCG
GATGGGGGATGGTTAAACGGTTATTATACCACAAGTAGTAGCTCTGAGCTTATTGCTATTGAGATAGAAAAACACCTGGC
TTTAACTTGCATTTTAAAAAATGTAATACGCAATCACCATAAACTTTATTCGGGTGGGGTATAA

Protein sequence : 
MLAVLKGIPLIQDIRAEGNSRSWIMTIDGHPARGEIFSEAFSISLFLNDLESLPKPCLAYVTLLLAAHPDVHDYAIQLTA
DGGWLNGYYTTSSSSELIAIEIEKHLALTCILKNVIRNHHKLYSGGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spiC AEZ06299.1 pathogenicity island 2 secreted effector protein Virulence SPI-2 Protein 1e-49 100
spiC NP_456135.1 putative pathogenicity island 2 secreted effector protein Virulence SPI-2 Protein 1e-49 100
spiC NP_805064.1 pathogenicity island secreted effector protein Virulence SPI-2 Protein 1e-49 100
spiC AAC44300.1 SpiC Virulence SPI-2 Protein 9e-50 100
ssaB NP_460358.1 secreted effector protein Virulence SPI-2 Protein 1e-49 100
spiC AEZ06297.1 pathogenicity island 2 secreted effector protein Virulence SPI-2 Protein 4e-49 99
spiC AEZ06300.1 pathogenicity island 2 secreted effector protein Virulence SPI-2 Protein 4e-49 99
spiC AEZ06295.1 pathogenicity island 2 secreted effector protein Virulence SPI-2 Protein 2e-49 99
spiC AEZ06296.1 pathogenicity island 2 secreted effector protein Virulence SPI-2 Protein 2e-49 99
spiC AEZ06298.1 pathogenicity island 2 secreted effector protein Virulence SPI-2 Protein 1e-49 99
ssaB YP_216401.1 secretion system apparatus protein SsaB Virulence SPI-2 Protein 2e-49 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spiC YP_008308829.1 pathogenicity island chaperone protein SpiC VFG0494 Protein 3e-50 100