Gene Information

Name : SEEB0189_12460 (SEEB0189_12460)
Accession : YP_008308807.1
Strain : Salmonella enterica CFSAN000189
Genome accession: NC_021844
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2532539 - 2533840 bp
Length : 1302 bp
Strand : -
Note : Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGAAGAATGAATTGATGCAACGTCTGAGGCTGAAATATCCGCCCCCCGATGGTTATTGTCGATGGGGCCGAATTCAGGA
TGTCAGCGCAACGTTGTTAAATGCGTGGTTGCCTGGGGTATTTATGGGTGAGTTGTGCTGTATAAAGCCTGGAGAAGAAC
TTGCTGAAGTCGTGGGGATTAATGGCAGCAAAGCTTTGCTATCTCCTTTTACGAGTACAACCGGACTTCACTGCGGGCAG
CAAGTGATGGCCTTAAGGCGACGCCATCAGGTTCCCGTGGGCGAAGCGTTATTAGGGCGAGTCATTGATGGTTTTGGTCG
TCCCCTTGATGGCCGCGAACTGCCAGAAGTCTGCTGGAAAGACTATGATGCAATGCCTCCTCCCGCAATGGTTCGACAGC
CTATCACTCAACCATTAATGACGGGGATTCGCGCTATTGATAGCGTTGCGACCTGTGGCGAAGGGCAACGAGTGGGGATT
TTTTCTGCTCCTGGCGTGGGGAAAAGCACGCTTCTGGCGATGCTGTGTAATGCGCCAGACGCAGACTGCAATGTTCTGGT
GTTAATTGGTGAACGTGGACGAGAAGTCCGCGAGTTCATCGATTTTACACTGTCTGAAGAGACCCGAAAACGTTGTGTCA
TTGTTGTCGCAACCTCTGACAGACCCGCCTTAGAGCGCGTGAGGGCGCTGTTTGTGGCCACCACGATAGCAGAATTTTTT
CGCGATAATGGAAAGCGAGTCGTCTTGCTTGCCGACTCACTGACGCGTTATGCCAGGGCCGCACGGGAAATCGCTCTGGC
CGCCGGAGAGACCGCGGTTTCTGGAGAATATCCGCCAGGCGTATTTAGTGCATTGCCACGACTTTTAGAACGTACAGGAA
TGGGGGAAAAAGGCAGTATTACCGCATTTTATACGGTACTGGTGGAAGGCGATGATATGAATGAGCCGTTGGCGGATGAA
GTCCGTTCACTGCTTGACGGACATATTGTGCTATCCCGACGGCTTGCAGAGAGGGGGCATTATCCTGCCATTGACGTGTT
GGCAACGCTCAGCCGCGTTTTTCCAGTCGTTACCAGCCATGAGCATCGTCAACTGGCGGCGATATTGCGACGGTGCCTGG
CGCTTTACCAGGAGGTTGAACTGTTAATACGCATTGGGGAATACCAGCGAGGAGTTGATACTGATACTGACAAAGCCATT
GATGCCTATCCGGATATTTGTACATTTTTGCGACAAAGTAAGGATGAAGTATGCGGACCCGAGCTACTTATAGAAAAATT
ACACCAAATACTCACCGAGTGA

Protein sequence :
MKNELMQRLRLKYPPPDGYCRWGRIQDVSATLLNAWLPGVFMGELCCIKPGEELAEVVGINGSKALLSPFTSTTGLHCGQ
QVMALRRRHQVPVGEALLGRVIDGFGRPLDGRELPEVCWKDYDAMPPPAMVRQPITQPLMTGIRAIDSVATCGEGQRVGI
FSAPGVGKSTLLAMLCNAPDADCNVLVLIGERGREVREFIDFTLSEETRKRCVIVVATSDRPALERVRALFVATTIAEFF
RDNGKRVVLLADSLTRYARAAREIALAAGETAVSGEYPPGVFSALPRLLERTGMGEKGSITAFYTVLVEGDDMNEPLADE
VRSLLDGHIVLSRRLAERGHYPAIDVLATLSRVFPVVTSHEHRQLAAILRRCLALYQEVELLIRIGEYQRGVDTDTDKAI
DAYPDICTFLRQSKDEVCGPELLIEKLHQILTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 0.0 99
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 0.0 99
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 0.0 99
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 0.0 99
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 0.0 99
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-110 59
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-95 55
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 9e-75 52
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-88 51
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-88 51
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-76 51
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-76 51
escN AAL57542.1 EscN Virulence LEE Protein 3e-88 51
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-88 51
escN AAC31513.1 L0034 Virulence LEE Protein 3e-88 51
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-88 51
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-88 51
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-88 51
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-88 51
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-88 51
escN CAI43874.1 EscN protein Virulence LEE Protein 9e-89 51
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-88 51
escN AAK26715.1 EscN Virulence LEE Protein 3e-88 51
escN AAC38383.1 EscN Virulence LEE Protein 2e-88 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-87 51
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-86 51
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-75 51
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-72 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-87 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-87 50
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 6e-74 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-87 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-87 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-86 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-87 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-87 50
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-73 50
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-73 50
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-80 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-88 50
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-74 48
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-74 48
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-74 48
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-64 47
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-65 45
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-65 45
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-65 45
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-65 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-67 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 6e-64 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG0515 Protein 0.0 99
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG0390 Protein 3e-94 57
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG0192 Protein 3e-95 55
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG0048 Protein 4e-91 53
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG0812 Protein 1e-88 51
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG0730 Protein 1e-88 51
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG2144 Protein 4e-81 51
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG1254 Protein 2e-72 51
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG2499 Protein 2e-64 47
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG1008 Protein 2e-69 45
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG0555 Protein 7e-66 45
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG1778 Protein 2e-65 45
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG2459 Protein 4e-68 43
SEEB0189_12460 YP_008308807.1 type III secretion system ATPase VFG2331 Protein 4e-63 43