Gene Information

Name : tpx (SEEB0189_11095)
Accession : YP_008308537.1
Strain : Salmonella enterica CFSAN000189
Genome accession: NC_021844
Putative virulence/resistance : Virulence
Product : lipid hydroperoxide peroxidase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2252799 - 2253305 bp
Length : 507 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homolog

DNA sequence : 
ATGTCACAGACTGTACATTTCCAGGGTAACCCGGTCACCGTTGCCAACGTTATTCCGCAGGCTGGTAGCAAAGCACAGGC
TTTTACTCTTGTCGCAAAAGATTTGTCTAACGTTTCCCTCAGCCAATATGCAGGCAAACGCAAAGTGCTGAATATTTTCC
CAAGCATTGATACTGGCGTATGCGCCGCATCAGTTCGTAAGTTTAATCAACTGGCCACAGAAGTGGAGAATACCGTCGTA
TTGTGCGTTTCTGCTGACCTGCCTTTTGCACAGTCGCGTTTTTGCGGCGCGGAAGGCCTGAGCAACGTTATTACGCTTTC
CACTCTGCGTAATAACGAGTTTCTGAAAAACTACGGCGTCGAAATCGTTGACGGTCCGCTGAAAGGTTTGGCGGCGCGCG
CAGTCATCGTGCTTGACGAAAACGACAACGTTATTTTCAGCCAGTTGGTGGATGAAATCACCCACGAGCCGGATTACGAC
GCCGCGCTTAATGTCCTGAAGGCATAA

Protein sequence : 
MSQTVHFQGNPVTVANVIPQAGSKAQAFTLVAKDLSNVSLSQYAGKRKVLNIFPSIDTGVCAASVRKFNQLATEVENTVV
LCVSADLPFAQSRFCGAEGLSNVITLSTLRNNEFLKNYGVEIVDGPLKGLAARAVIVLDENDNVIFSQLVDEITHEPDYD
AALNVLKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 4e-34 48
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-34 48
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 3e-34 48
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-34 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_008308537.1 lipid hydroperoxide peroxidase VFG0087 Protein 6e-35 48