Gene Information

Name : guaA (SEEB0189_07010)
Accession : YP_008307744.1
Strain : Salmonella enterica CFSAN000189
Genome accession: NC_021844
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1407381 - 1408958 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGACGGAAAACATTCATAAGCATCGCATCCTCATTCTGGACTTCGGTTCTCAGTACACTCAACTGGTTGCGCGCCGCGT
GCGTGAGCTGGGTGTTTACTGTGAACTGTGGGCGTGGGATGTGACAGAAGCACAAATTCGTGACTTCAACCCAAGCGGCA
TTATTCTTTCCGGCGGCCCGGAAAGCACCACCGAAGAAAACAGCCCGCGCGCGCCGCAGTATGTCTTTGAAGCAGGCGTG
CCGGTATTTGGCGTCTGCTACGGGATGCAGACCATGGCGATGCAGCTTGGCGGTCATGTAGAAGGTTCTAATGAGCGTGA
ATTTGGTTACGCGCAGGTCGAAGTATTGACCGACAGCGCGCTGGTTCGCGGTATTGAAGATTCCCTGACCGCCGACGGCA
AACCGCTGCTGGACGTGTGGATGAGCCACGGCGATAAAGTGACGGCGATTCCGGCCGACTTCGTAACCGTCGCCAGCACC
GAGAGCTGCCCGTTCGCCATCATGGCTAACGAAGAAAAACGCTTCTACGGCGTACAGTTCCACCCGGAAGTGACCCACAC
CCGCCAGGGTATGCGCATGCTGGAGCGTTTTGTGCGTGATATCTGCCAGTGTGAAGCGCTGTGGACGCCGGCGAAGATCA
TCGACGACGCCGTGGCGCGCATTCGCGAGCAGGTAGGCGACGATAAAGTGATCCTCGGTCTCTCCGGCGGTGTGGATTCT
TCCGTCACCGCGATGCTGCTGCACCGCGCGATCGGTAAAAATCTGACCTGTGTATTCGTCGACAACGGCCTGCTGCGTCT
CAACGAAGCCGAGCAGGTGATGGACATGTTTGGCGACCATTTTGGCCTGAATATCGTTCACGTTCCGGCGGAAGAGCGCT
TCCTGTCCGCGCTGGCTGGTGAGAACGATCCGGAAGCCAAGCGTAAGATCATCGGCCGCGTTTTCGTTGAAGTGTTCGAC
GAAGAAGCGCTCAAACTGGAAGACGTGAAATGGCTGGCGCAGGGCACCATCTACCCTGACGTTATCGAATCTGCGGCGTC
TGCAACCGGTAAAGCGCACGTCATCAAATCTCACCACAATGTCGGCGGCCTGCCGAAAGAGATGAAGATGGGTCTGGTTG
AACCGCTGAAAGAGCTGTTCAAAGACGAAGTGCGTAAGATTGGTCTGGAGCTGGGCCTGCCGTACGACATGCTGTACCGT
CACCCGTTCCCGGGGCCGGGCCTCGGCGTACGCGTACTGGGCGAAGTGAAGAAAGAGTACTGCGACCTGCTGCGTCGCGC
GGACGCTATCTTCATTGAAGAGCTGCGCAAAGCGGATCTGTACGACAAAGTCAGTCAGGCGTTTACCGTCTTCCTGCCGG
TCCGTTCCGTAGGCGTGATGGGCGATGGTCGTAAGTACGATTGGGTGGTCTCCCTGCGTGCCGTCGAAACCATCGACTTT
ATGACCGCGCACTGGGCGCACCTGCCGTATGACTTCCTCGGTCGTGTTTCCAACCGCATCATCAATGAAGTCAACGGGAT
TTCCCGTGTGGTGTATGACATCAGCGGTAAACCACCGGCTACCATTGAGTGGGAATAA

Protein sequence :
MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGV
PVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPADFVTVAST
ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEERFLSALAGENDPEAKRKIIGRVFVEVFD
EEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-127 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-128 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-128 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-110 48