Gene Information

Name : SEEB0189_05760 (SEEB0189_05760)
Accession : YP_008307503.1
Strain : Salmonella enterica CFSAN000189
Genome accession: NC_021844
Putative virulence/resistance : Virulence
Product : pathogenicity island 1 effector protein SipA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1115800 - 1117857 bp
Length : 2058 bp
Strand : +
Note : cell invasion protein A; actin-binding; required for entry of the Salmonella into the host cell; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGGTTACAAGTGTAAGGACTCAGCCCCCCGTCATAATGCCAGGTATGCAGACCGAGATCAAAACGCAGGCCACGAATCT
TGCGGCGAATCTTTCCGCAGTCAGAGAAAGTGCCACAACGACGCTGTCAGGGGAAATTAAAGGCCCGCAACTGGAAGATT
TTCCCGCGCTGATCAAACAGGCGAGTCTGGATGCATTGTTTAAATGCGGGAAAGACGCTGAGGCGTTAAAAGAAGTTTTT
ACCAATTCAAATAATGTCGCCGGTAAGAAAGCGATAATGGAGTTTGCCGGGCTCTTTCGTTCAGCGCTCAACGCCACCAG
TGATTCTCCTGAGGCGAAGACGCTACTGATGAAGGTGGGGGCAGAGTATACCGCGCAAATCATAAAAGATGGCCTGAAAG
AAAAGTCAGCTTTTGGGCCATGGCTGCCAGAAACAAAGAAAGCGGAAGCGAAGCTGGAAAACCTGGAAAAGCAGCTGTTA
GATATTATCAAAAATAACACTGGTGGTGAATTAAGTAAATTATCGACGAATCTTGTTATGCAGGAGGTGATGCCCTATAT
TGCCAGCTGCATTGAACATAACTTTGGCTGTACGTTAGATCCGTTAACCCGCAGCAATCTTACGCACCTTGTTGACAAAG
CGGCGGCGAAGGCGGTTGAGGCGCTTGATATGTGCCACCAAAAATTAACGCAAGAGCAGGGTACCAGCGTAGGACGGGAA
GCCCGGCACCTTGAAATGCAAACGTTGATACCCCTGCTGCTACGTAATGTTTTTGCACAAATTCCTGCAGATAAACTGCC
TGACCCTAAAATTCCGGAACCTGCGGCTGGACCAGTACCTGATGGTGGGAAAAAAGCAGAACCTACGGGTATTAATATCA
ATATTAATATTGATAGCAGTAACCATAGCGTGGATAACAGTAAGCATATTAACAATAGCCGAAGCCATGTCGATAATAGC
CAGCGCCATATCGATAATAGCAACCATGATAATAGCCGGAAGACGATTGATAATAGCCGAACATTTATTGATAACAGCCA
ACGCCATGGCGAGTCACACCATTCGACTAACAGCAGCAACGTAAGTCATAGTCATTCGCGTGTGGATTCGACTACGCATC
AAACGGAGACGGCACACAGCGCCAGCACAGGGGCAATTGACCATGGCATCGCGGGTAAAATTGACGTCACGGCTCATGCG
ACGGCAGAGGCTGTGACCAACGCTTCATCCGAAAGTAAAGATGGAAAGGTGGTCACGTCAGAAAAGGGCACTACGGGTGA
AACAACCTCTTTTGATGAAGTCGATGGCGTAACCAGCAAGAGCATTATCGGCAAGCCGGTACAGGCCACGGTGCACGGCG
TTGATGATAATAAACAGCAAAGCCAGACGGCAGAGATTGTGAATGTGAAGCCGCTTGCCAGTCAACTGGCTGGCGTCGAG
AATGTTAAAACCGATACCTTACAATCAGACACGACGGTAATTACAGGTAATAAAGCCGGTACGACCGATAATGATAATAG
TCAGACAGATAAGACTGGCCCATTTTCTGGTTTGAAGTTTAAGCAAAATAGTTTCCTCTCAACAGTACCGAGCGTTACGA
ATATGCATTCAATGCATTTCGACGCCCGTGAGACGTTTTTGGGTGTGATACGTAAAGCCCTGGAGCCAGATACCTCCACA
CCGTTCCCTGTACGCAGAGCGTTTGACGGCTTGCGTGCGGAAATATTACCCAATGACACGATAAAGAGTGCAGCGTTGAA
AGCGCAATGTAGCGATATTGACAAGCACCCAGAATTGAAAGCGAAAATGGAGACTCTCAAAGAGGTCATTACTCATCATC
CACAAAAAGAAAAACTGGCTGAGATTGCACTGCAGTTTGCCAGAGAGGCGGGGCTGACCAGGCTAAAAGGGGAAACTGAC
TATGTGTTAAGTAATGTGCTGGACGGACTTATCGGAGACGGTAGCTGGCGAGCTGGCCCGGCTTACGAGTCATACCTGAA
TAAACCTGGCGTGGATCGGGTTATTACTACCGTTGATGGCTTGCACATGCAGCGTTAA

Protein sequence :
MVTSVRTQPPVIMPGMQTEIKTQATNLAANLSAVRESATTTLSGEIKGPQLEDFPALIKQASLDALFKCGKDAEALKEVF
TNSNNVAGKKAIMEFAGLFRSALNATSDSPEAKTLLMKVGAEYTAQIIKDGLKEKSAFGPWLPETKKAEAKLENLEKQLL
DIIKNNTGGELSKLSTNLVMQEVMPYIASCIEHNFGCTLDPLTRSNLTHLVDKAAAKAVEALDMCHQKLTQEQGTSVGRE
ARHLEMQTLIPLLLRNVFAQIPADKLPDPKIPEPAAGPVPDGGKKAEPTGINININIDSSNHSVDNSKHINNSRSHVDNS
QRHIDNSNHDNSRKTIDNSRTFIDNSQRHGESHHSTNSSNVSHSHSRVDSTTHQTETAHSASTGAIDHGIAGKIDVTAHA
TAEAVTNASSESKDGKVVTSEKGTTGETTSFDEVDGVTSKSIIGKPVQATVHGVDDNKQQSQTAEIVNVKPLASQLAGVE
NVKTDTLQSDTTVITGNKAGTTDNDNSQTDKTGPFSGLKFKQNSFLSTVPSVTNMHSMHFDARETFLGVIRKALEPDTST
PFPVRRAFDGLRAEILPNDTIKSAALKAQCSDIDKHPELKAKMETLKEVITHHPQKEKLAEIALQFAREAGLTRLKGETD
YVLSNVLDGLIGDGSWRAGPAYESYLNKPGVDRVITTVDGLHMQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sipA NP_461803.1 secreted effector protein Virulence SPI-1 Protein 0.0 99
sipA YP_217801.1 cell invasion protein Virulence SPI-1 Protein 0.0 99
sipA NP_457276.1 pathogenicity island 1 effector protein (function unknown) Virulence SPI-1 Protein 0.0 98
sipA NP_806485.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SEEB0189_05760 YP_008307503.1 pathogenicity island 1 effector protein SipA VFG0543 Protein 0.0 99