Gene Information

Name : spaK (SEEB0189_05695)
Accession : YP_008307490.1
Strain : Salmonella enterica CFSAN000189
Genome accession: NC_021844
Putative virulence/resistance : Virulence
Product : type III secretion system chaperone SpaK
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1104160 - 1104567 bp
Length : 408 bp
Strand : +
Note : involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
ATGCAACATTTGGATATCGCTGAATTAGTTCGTTCCGCACTGGAAGTAAGTGGTTGCGATCCTTCACTCATCGGAGGAAT
AGATAGCCATTCAACAATTGTTCTGGATTTATTTGCATTGCCAAGTATCTGTATCAGCGTCAAGGACGATGATGTATGGA
TCTGGGCGCAATTGGGTGCTGACAGCATGGTGGTATTACAACAGCGGGCTTATGAAATCTTAATGACCATCATGGAAGGA
TGCCATTTTGCCCGCGGCGGGCAATTACTACTGGGGGAGCAGAATGGGGAGCTAACGCTTAAAGCCTTAGTGCATCCGGA
TTTTTTATCTGACGGTGAAAAGTTCTCTACTGCCTTGAATGGGTTTTACAACTATCTGGAAGTTTTTAGTCGGTCGCTAA
TGAGATGA

Protein sequence :
MQHLDIAELVRSALEVSGCDPSLIGGIDSHSTIVLDLFALPSICISVKDDDVWIWAQLGADSMVVLQQRAYEILMTIMEG
CHFARGGQLLLGEQNGELTLKALVHPDFLSDGEKFSTALNGFYNYLEVFSRSLMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spak NP_457289.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 1e-51 100
spak NP_806498.1 virulence-associated secretory protein Virulence SPI-1 Protein 1e-51 100
invB NP_461816.1 secretion chaperone Virulence SPI-1 Protein 1e-51 100
invB YP_217814.1 surface presentation of antigens; secretory proteins Virulence SPI-1 Protein 1e-51 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaK YP_008307490.1 type III secretion system chaperone SpaK VFG0556 Protein 4e-52 100