Gene Information

Name : M641_05055 (M641_05055)
Accession : YP_008298523.1
Strain : Listeria monocytogenes R2-502
Genome accession: NC_021838
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 963627 - 964799 bp
Length : 1173 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
GTGGCTAATGAATATGCGCAAGATACGGCTGTGATTAAAGCGAGCCTCGGGATTGATAAAGAGACAGGTGCGCTTAATAC
GCCAATTCATTTATCGTCTACTTTCCATCAGCATGACTTTGATAATTATCACGCTTATGATTATGCGAGAAGTGGGAACC
CAACGAGAGAAAAAGTGGAACAAGCGATTGCGGAACTGGAAGGTGGTACGAATGGTTTTGCCTTTGCTAGTGGGATGGCG
GCTGTTTCTGCAGCGCTCTTTACTCTTTCTAAGGGAGACCATTTTATCATTGCGAAAGATGTGTACGGCGGGACGTTTCG
TTTGGTGGAGCAAGTGTTGCCGCGTTTTGGGATTACGCATACTTTTGTTGATACGACAAATATTGACGAAGTTGCGAAGG
CATTTCAAGCGAATACGAAACTGGTTTACTTGGAAACACCTTCTAATCCGTTGCTGCATGTGACAGATATTCGGACTGTT
GCAAAACTTGCGAAAGCGAATGGGTGTTATACGTTTGTTGATAATACATTTTTGACGCCGTTAATTCAAAAACCGTTAGA
ATTAGGTGCAGACTTGGTTATTCATAGTGCGACGAAATTTCTTGGAGGGCATAGTGATATTTTGGCGGGGCTAATTGTCA
CCAATAATCCTAATCTGGCTGAAGCAGTGTACTTTTTGCAAAATTCGACTGGTGGGGTTCTTGGAGTGCAGGATTCGTGG
TTGTTATTGCGCGGACTAAAAACACTTTCTGTGCGGATGAAGGCTGGGACGGAAACAGCGGAGAAAATTGCGCTATTTTT
AAATGCGGAGCCAGATGTGGTGGCAGTGCATTATCCGGGGTTACCTTCTCATGCGGGTTATGACATTCAAGTGGAACAGG
CGACAAGTGGCGGGGCCGTTTTATCGTTTGATTTAGGCAGTGAGGAAGCTGTGCGAGAACTAGTAACACATTTGGAATTG
CCGGTATTTTCTGTGAGTTTGGGCGCGGTGGAGAGTATTCTTTCTTACCCGGCTAAAATGTCTCATGCGGCTGTTCCGGA
AGAGGAGCGTTTGGCGCAAGGAATTACGCCAGGATTATTACGTTTTTCAGCTGGACTAGAAGATGCCGATGACTTGATTG
CTGATTTAAAACAAGCACTTTCTTTCATTAAGAAGGGAAGTGTTGCGAAATGA

Protein sequence :
MANEYAQDTAVIKASLGIDKETGALNTPIHLSSTFHQHDFDNYHAYDYARSGNPTREKVEQAIAELEGGTNGFAFASGMA
AVSAALFTLSKGDHFIIAKDVYGGTFRLVEQVLPRFGITHTFVDTTNIDEVAKAFQANTKLVYLETPSNPLLHVTDIRTV
AKLAKANGCYTFVDNTFLTPLIQKPLELGADLVIHSATKFLGGHSDILAGLIVTNNPNLAEAVYFLQNSTGGVLGVQDSW
LLLRGLKTLSVRMKAGTETAEKIALFLNAEPDVVAVHYPGLPSHAGYDIQVEQATSGGAVLSFDLGSEEAVRELVTHLEL
PVFSVSLGAVESILSYPAKMSHAAVPEEERLAQGITPGLLRFSAGLEDADDLIADLKQALSFIKKGSVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-75 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-76 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-75 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M641_05055 YP_008298523.1 cystathionine beta-lyase BAC0207 Protein 1e-54 43