Gene Information

Name : SE451236_00080 (SE451236_00080)
Accession : YP_008263116.1
Strain : Salmonella enterica 08-1736
Genome accession: NC_021820
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 16338 - 18233 bp
Length : 1896 bp
Strand : +
Note : catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Hom

DNA sequence :
ATGTCTACAACAACGTTAACCCGCCGCGAGCAGCGCGCTAAAGCCCAGCATTTTATCGATACGCTGGAAGGCACCGCGTT
TCCCAACTCGAAACGCATCTACGTGACCGGTTCGCAGCATGATATTCGCGTACCGATGCGCGAAATTCAACTTAGCCCCA
CGCTCATCGGCGGCAGTAAAGACAACCCGCAGTTTGAAGAGAACGAAGCCGTACCGGTATACGACACCTCCGGCCCCTAT
GGCGATCCTGAGGTGGCGATTAACGTCCAGCAGGGTCTGGCGAAACTGCGCCAGCCATGGATTGACGCACGTAACGATAG
CGAAGAATTAGACGACCGTAGCTCGGCTTATACCAGAGAACGTCTGGCCGACGATGGCCTGGACGATCTGCGTTTTACCG
GCCTGCTGACGCCAAAACGCGCTAAAGCGGGCAAGCGCGTCACCCAGTTACACTACGCCCGCAAGGGGATCGTCACTCCC
GAAATGGAGTTCATCGCCATCCGTGAAAATATGGGCCGTGAGCGCATTCGCAGTGAAGTGCTGCGCCACCAGCATCCGGG
GATGAACTTTGGCGCGCGCCTGCCGGAAAACATTACGCCGGAATTCGTGCGTGATGAAGTCGCCGCGGGCCGCGCGATTA
TTCCCGCCAACATCAACCACCCGGAATCGGAGCCGATGATTATCGGCCGCAACTTCCTGGTCAAAGTGAATGCCAACATC
GGTAACTCGGCGGTCACCTCCTCCATCGAAGAAGAGGTGGAAAAACTGGTGTGGTCAACCCGCTGGGGCGCGGACACGGT
GATGGACCTCTCCACCGGTCGCTATATTCATGAAACCCGCGAATGGATCCTGCGTAACAGCCCGGTACCGATCGGCACCG
TCCCGATCTACCAGGCGCTGGAGAAGGTCAACGGGATCGCCGAAGATCTTACCTGGGAAGCGTTCCGCGACACGCTACTG
GAGCAGGCTGAACAGGGCGTCGACTACTTCACCATTCACGCGGGCGTGCTGCTGCGCAACGTGCCAATGACCGCCAAACG
CCTGACCGGGATTGTCTCACGCGGCGGTTCCATCATGGCAAAGTGGTGTCTCTCCCATCACAAAGAGAACTTCCTGTTCG
AACATTTCCGCGAGATTTGTGAAATTTGCGCCGCCTACGACGTCTCCTTGTCGCTGGGCGACGGCCTGCGCCCCGGCTCC
ATTCAGGATGCCAACGACGAAGCGCAGTTCTCCGAGCTGCATACGCTGGGCGAATTGACCAAAATCGCCTGGGAATACGA
CGTGCAGGTGATGATTGAAGGCCCGGGCCACGTACCCATGCATATGATCCAGCGCAACATGACCGAAGAGCTGGAGAGCT
GCCATGAAGCACCGTTCTACACCTTAGGGCCATTGACCACCGATATCGCGCCGGGCTATGACCACTTCACCTCCGGGATC
GGTGCCGCGATGATCGGCTGGTTTGGCTGCGCGATGCTGTGTTATGTGACGCCGAAAGAACACCTCGGCCTGCCGAACAA
AGAAGATGTGAAGCAGGGGCTAATCACCTACAAAATCGCCGCCCACGCCGCGGATTTAGCCAAAGGACATCCGGGCGCGC
AGATCCGCGATAACGCCATGTCGAAAGCGCGCTTTGAATTCCGCTGGGAAGATCAGTTTAACCTCGCGCTCGACCCGTTC
ACCGCCCGCGCTTATCACGATGAAACCCTGCCGCAGGAGTCCGGCAAGGTTGCCCACTTCTGCTCCATGTGCGGGCCGAA
GTTCTGCTCGATGAAAATCAGCCAGGAGGTCCGCGACTACGCCGCCGCACAAACTATTGAAATCGGCATGGCGGATATGT
CAGAGGACTTCCGCGCCAAAGGCGGCGAAATTTATCTCAAGCGGGAGGAAGCCTGA

Protein sequence :
MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPY
GDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARKGIVTP
EMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRNVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEIGMADMSEDFRAKGGEIYLKREEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 70