Gene Information

Name : CFSAN002050_03635 (CFSAN002050_03635)
Accession : YP_008258688.1
Strain : Salmonella enterica CFSAN002050
Genome accession: NC_021818
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 439161 - 441056 bp
Length : 1896 bp
Strand : -
Note : catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Hom

DNA sequence :
ATGTCTACAACAACGTTAACCCGCCGCGAGCAGCGCGCTAAAGCCCAGCATTTTATCGATACGCTGGAAGGGACTGCCTT
TCCCAACTCGAAACGCATCTACGTGACCGGTTCGCAGCATAATATTCGCGTACCGATGCGCGAAATTCAACTGAGCCCGA
CGCTCATCGGCGGCAGCAAAGACAACCCGCAGTTTGAAGAGAACGAAGCCGTGCCGGTGTACGACACCTCCGGCCCGTAT
GGCGATCCTGAGGTGGCGATTAACGTCCAGCAGGGTCTGGCGAAACTGCGCCAGCCGTGGATTGACGCACGTAACGATAG
CGAAGAACTAGACGACCGTAGCTCGGCTTACACCAAAGAACGTCTGGCCGACGATGGCCTGGACGATCTGCGTTTTACTG
GCCTGCTGACGCCGAAACGCGCTAAAGCGGGCAAGCGCGTCACCCAGTTACATTACGCCCGCCAGGGGATCGTCACTCCC
GAAATGGAGTTCATCGCCATCCGTGAAAATATGGGCCGCGAGCGCATTCGCAGTGAAGTGCTGCGCCACCAGCATCCGGG
CATGAACTTTGGCGCGCGCCTGCCGGAAAACATTACGCCGGAATTCGTGCGTGATGAAGTGGCTGCGGGCCGCGCGATTA
TTCCTGCCAACATCAACCACCCGGAATCGGAGCCGATGATTATCGGCCGCAACTTCCTGGTCAAAGTGAATGCCAATATC
GGCAACTCGGCGGTCACCTCCTCCATCGAAGAAGAGGTGGAGAAGCTGGTCTGGGCGACGCGCTGGGGCGCGGATACGGT
AATGGACCTTTCCACCGGCCGCTATATTCACGAAACCCGTGAGTGGATCCTACGTAACAGCCCGGTACCGATCGGCACCG
TCCCGATCTACCAGGCGCTGGAAAAGGTTAACGGGATCGCCGAAGATCTTACCTGGGAAGCGTTCCGCGACACGCTGCTG
GAGCAGGCTGAACAGGGCGTCGACTACTTCACCATCCACGCGGGCGTGCTGCTGCGCTACGTGCCGATGACCGCCAAGCG
CCTGACCGGCATTGTCTCACGCGGCGGTTCAATCATGGCGAAATGGTGCCTCTCCCATCACAAAGAGAACTTCCTGTTCG
AACATTTCCGCGAGATCTGCGAAATCTGTGCCGCCTACGACGTTTCCCTGTCGCTGGGCGACGGCCTGCGCCCCGGCTCC
ATTCAGGACGCCAACGACGAAGCGCAGTTCTCCGAGCTGCATACGCTGGGCGAGCTGACCAAAATCGCCTGGGAATACGA
CGTGCAGGTGATGATTGAAGGCCCGGGCCACGTGCCGATGCATATGATTCAGCGCAACATGACCGAAGAGCTGGAGAGCT
GCCACGAAGCGCCGTTCTACACCTTAGGGCCGTTGACCACCGATATCGCGCCGGGCTATGACCACTTCACCTCCGGCATT
GGCGCCGCGATGATCGGCTGGTTTGGCTGCGCGATGCTGTGTTACGTGACGCCGAAAGAACATCTCGGCCTGCCGAACAA
AGAAGATGTGAAACAGGGGCTGATCACCTACAAAATCGCCGCCCACGCAGCGGATTTAGCCAAAGGCCATCCGGGCGCGC
AGATCCGCGATAACGCGATGTCGAAAGCGCGCTTCGAATTCCGCTGGGAAGATCAGTTTAACCTCGCGCTCGACCCGTTC
ACCGCCCGCGCTTATCACGATGAAACCCTGCCACAGGAGTCCGGCAAGATTGCCCACTTCTGCTCCATGTGCGGGCCGAA
ATTCTGCTCGATGAAAATCAGCCAGGAGGTCCGCGACTACGCCGCCGCGCAAGCCATTGAAGTCGGCATGGCGGATATGT
CGGAAAACTTCCGCGCCAAAGGTGGCGAAATCTATCTCAAGCGGGAGGAAGCCTGA

Protein sequence :
MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHNIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPY
GDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTKERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARQGIVTP
EMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKIAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 70