Gene Information

Name : CFSAN002050_20710 (CFSAN002050_20710)
Accession : YP_008262013.1
Strain : Salmonella enterica CFSAN002050
Genome accession: NC_021818
Putative virulence/resistance : Virulence
Product : pathogenicity island 1 effector protein SipA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3955533 - 3957590 bp
Length : 2058 bp
Strand : -
Note : cell invasion protein A; actin-binding; required for entry of the Salmonella into the host cell; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGGTTACAAGTGTAAGGACTCAGCCCCCCGTCATAATGCCAGGTATGCAGGCCGAGATCAAAACGCAGGCCACGAATCT
TGCGGCGAATCTTTCCGCAGTCAGAGAAAGTGCCACAACGACGCTGTCAGGGGAAATTAGAGGCCCGCAACTGGAAGATT
TTCCCGCGCTGATCAAACAGGCGAGTCTGGATGCGTTGTTTAAATGCGGGAAAGACGCTGAGGCGTTAAAAGAAGTTTTT
ACCAATTCAAATAATGTCGCCAGTAAGAAAGCGATAATGGAATTTGCCGGGCTCTTTCGTTCAGCGCTCAACGCCACCAG
TGATTCTCCTGCGGCGAAGACGCTACTGATGAAGGTGGGGGCAGAGTATACCGCGCAAATCATAAAAGATGGCCTGAAAG
AAAAGTCAGCTTTTGGGCCATGGCTGCCAGAAACAAAGAAAGCGGAAGCGAAGCTGGAAAACCTGGAAAAGCAGCTGTTA
GATATCATCAAAAATAACACTGGCGGTGAATTAAGTAAATTATCGACGAATCTTGTTATGCAGGAGGTGATGCCCTATAT
TGCCAGCTGCATTGAACATAACTTTGGCTGTACGTTGGATCCGTTAACCCGCAGCAGTCTTACGCAGCTTGTTGACAAAG
CGGCGGCGAAGGCGGTTGAGGCGCTTGATATGTGCCACCAAAAATTAACGCAAGAGCAGGGTACCAGCGTAGGACGGGAA
GCCCGGCACCTTGAAACGCAAACGTTGATACCCCTGCTGCTACGTAATGTTTTTGCACAAATTCCTGCAGATAAACTGCC
TGACCCTAAAATTCCGGAACCTGCGGCTGGACCAGTACCTGATGGTGGGAAAAAAGCAGAACCTACGGGTATTAATATCA
ATATTAATATTGATAGCAGTAGCCATAGCGTGGATAACAGTAAGCATATTAACAATAGCCGAAGCCATGTCGATAATAGC
CAGCGCCATATCGATAATAGCAACCATGATAATAGCCGGAAGACGATTGATAATAGCCGAACATTTATTGATAACAGCCA
ACGCCATGGCGAGTCACACCATTCGACTAACAGCAGTAACGTAAGTCATAGTCATTCGCGTGTGGATTCGACTACGCATC
AAACGGAGACGGCACACAGCGCCAGCACAGGGGCAATTGACCATGGCATCGCGGGTAAAATTGACGTCACGGCTCATGCG
ACGGCAGAAGCTGTGACCAATTCTTCATCCGAAAGTAAAGATGGAAAGGTGGTCACGTCAGAAAAGGGCACTACGGGTGA
AACACCCTCTTTTGATGAAGTTGATGGCGTAACCAGCAAGAACATTATCGGCAAGCCTGTACAGGCCACGGTGCACGGCG
TTGGTGATAATAAACAGCAAAGCCAGACGGCAGAGATTGTGAATGTGAAGCCGCTTGCCAGTCAACTGGCTGGCGTCGAG
AATGTTAAAATCGATACCTTACAATCAGACTCGACGGTAATTACAGGTAATAAAGCCGGTACGACCGATAATGATAATAG
CCAGACAGATAAGACTGGCCCATTTTCTGGTTTGAAGTTTAAGCAAAATAGTTTCCTCTCAACAGTACCGAGCGTTACGA
ATATGCATTCAATGCATTTCGACGCCCGTGAGGCGTTTTTGGGTGTGATACGTAAAGCCCTGGAGCCGGATGCCTCTACA
CCGTTTCCTGTACGCAGAGCGTTTGACGGCTTGCGTGCGGAAATATTACCCAATGACACGATAAAGAGTGCAGCGTTGAA
AGCGCAATGTAGCGATATTGACAAGCACCCAGAATTGAAAGCGAAAATGGATACGCTTAAAGAGGTCATTACTCATCATC
CACAAAAAGAAAAACTGGCTGAGATTGCACTGCAGTTTGCCAGAGAGGCGGGGCTGACCAGGCTAAAAGGGGAAACTGAC
TATGTGTTAAGTAATGTGCTGGACGGCCTTATCGGAGACGGTAGCTGGCGAGCTGGCCCGGCTTACGAGTCATACCTGAA
TAAACCTGGCGTGGATCGGGTTATTACTACCGTTGATGGCTTGCACATGCAGCGTTAA

Protein sequence :
MVTSVRTQPPVIMPGMQAEIKTQATNLAANLSAVRESATTTLSGEIRGPQLEDFPALIKQASLDALFKCGKDAEALKEVF
TNSNNVASKKAIMEFAGLFRSALNATSDSPAAKTLLMKVGAEYTAQIIKDGLKEKSAFGPWLPETKKAEAKLENLEKQLL
DIIKNNTGGELSKLSTNLVMQEVMPYIASCIEHNFGCTLDPLTRSSLTQLVDKAAAKAVEALDMCHQKLTQEQGTSVGRE
ARHLETQTLIPLLLRNVFAQIPADKLPDPKIPEPAAGPVPDGGKKAEPTGINININIDSSSHSVDNSKHINNSRSHVDNS
QRHIDNSNHDNSRKTIDNSRTFIDNSQRHGESHHSTNSSNVSHSHSRVDSTTHQTETAHSASTGAIDHGIAGKIDVTAHA
TAEAVTNSSSESKDGKVVTSEKGTTGETPSFDEVDGVTSKNIIGKPVQATVHGVGDNKQQSQTAEIVNVKPLASQLAGVE
NVKIDTLQSDSTVITGNKAGTTDNDNSQTDKTGPFSGLKFKQNSFLSTVPSVTNMHSMHFDAREAFLGVIRKALEPDAST
PFPVRRAFDGLRAEILPNDTIKSAALKAQCSDIDKHPELKAKMDTLKEVITHHPQKEKLAEIALQFAREAGLTRLKGETD
YVLSNVLDGLIGDGSWRAGPAYESYLNKPGVDRVITTVDGLHMQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sipA NP_806485.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 0.0 98
sipA NP_461803.1 secreted effector protein Virulence SPI-1 Protein 0.0 98
sipA YP_217801.1 cell invasion protein Virulence SPI-1 Protein 0.0 98
sipA NP_457276.1 pathogenicity island 1 effector protein (function unknown) Virulence SPI-1 Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CFSAN002050_20710 YP_008262013.1 pathogenicity island 1 effector protein SipA VFG0543 Protein 0.0 98