Gene Information

Name : CFSAN001921_02685 (CFSAN001921_02685)
Accession : YP_008253945.1
Strain : Salmonella enterica CFSAN001921
Genome accession: NC_021814
Putative virulence/resistance : Virulence
Product : pathogenicity island 1 effector protein StpP
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 545473 - 547104 bp
Length : 1632 bp
Strand : +
Note : GTP-activating protein/tyrosine phosphatase; facilitates bacterial survival in host cells; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGCTAAAGTATGAGGAGAGAAAATTGAATAATTTAACGTTGTCTTCGTTTTCAAAAGTTGGTGTGTCGAATGATGCCCG
ACTTTATATTGCTAAGGAAAATACTGATAAGGCATATGTTGCGCCTGAAAAATTTTCGTCAAAAGTATTAACCTGGCTTG
GAAAAATGCCGTTATTTAAAAACACTGAAGTGGTGCAAAAACATACGGAAAATATCAGAGTACAGGACCAAAAGATTTTA
CAGACATTTCTCCATGCACTAACGGAAAAATATGGGGAAACAGCGGTTAATGACGCACTGTTAATGTCCCGTATAAATAT
GAACAAACCCCTTACCCAACGTTTAGCAGTGCAGATCACGGAGTGTGTAAAAGCTGCTGACGAAGGGTTTATAAACCTTA
TTAAGAGCAAGGATAATGTTGGTGTCAGGAATGCCGCTTTAGTCATAAAAGGCGGCGATACAAAAGTGGCAGAAAAAAAT
AACGATGTTGGAGCAGAAAGTAAGCAACCTTTACTCGATATCGCGCTAAAGGGACTTAAAAGAACATTACCGCAACTGGA
ACAAATGGATGGAAATAGCCTGCGAGAAAACTTCCAGGAGATGGCTTCAGGTAACGGCCCGCTGCGTTCATTAATGACGA
ATTTACAGAATTTAAATAAAATTCCAGAGGCTAAACAACTTAATGATTATGTTACAACGTTAACAAATATTCAGGTCGGT
GTAGCCCGGTTCTCACAATGGGGAACCTGTGGAGGAGAGGTTGAGAGGTGGGTTGATAAAGCCTCTACTCATGAATTAAC
CCAGGCTGTAAAAAAAATTCACGTTATTGCTAAAGAACTGAAAAATGTTACAGCTGAACTTGAGAAAATAGAAGCCGGCG
CGCCAATGCCACAGACGATGAGCGGACCGACACTGGGCCTGGCACGATTTGCGGTCAGCAGCATTCCAATTAATCAGCAA
ACCCAGGTGAAACTGAGCGATGGAATGCCTGTGCCAGTGAATACGTTAACTTTTGACGGTAAGCCTGTGGCATTAGCCGG
TTCGTACCCAAAAAATACGCCGGATGCGCTGGAAGCGCATATGAAAATGCTTCTTGAAAAAGAATGCTCGTGCCTGGTGG
TGTTAACGTCGGAAGATCAGATGCAGGCAAAACAATTACCACCCTATTTCAGAGGGAGCTACACCTTTGGCGAGGTGCAT
ACCAACAGCCAAAAAGTGAGCTCAGCCAGTCAGGGAGAAGCGATAGACCAATACAATATGCAACTGTCCTGCGGGGAAAA
GCGGTATACAATCCCGGTATTGCATGTGAAAAATTGGCCAGATCACCAGCCGTTACCGTCTACGGATCAGTTAGAATACC
TGGCGGATAGGGTGAAAAATAGTAACCAAAATGGCGCGCCGGGGCGTAGTTCATCAGATAAGCATTTACCGATGATTCAT
TGTCTGGGCGGAGTGGGAAGAACCGGAACGATGGCGGCGGCCCTTGTACTTAAGGATAATCCTCATAGTAATCTGGAGCA
GGTACGTGCAGATTTCCGGGATTCACGGAACAATAGAATGCTGGAAGACGCCTCACAGTTTGTACAACTAAAAGCAATGC
AAGCCCAGTTGCTTATGACGACGGCAAGCTGA

Protein sequence :
MLKYEERKLNNLTLSSFSKVGVSNDARLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIRVQDQKIL
QTFLHALTEKYGETAVNDALLMSRINMNKPLTQRLAVQITECVKAADEGFINLIKSKDNVGVRNAALVIKGGDTKVAEKN
NDVGAESKQPLLDIALKGLKRTLPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQNLNKIPEAKQLNDYVTTLTNIQVG
VARFSQWGTCGGEVERWVDKASTHELTQAVKKIHVIAKELKNVTAELEKIEAGAPMPQTMSGPTLGLARFAVSSIPINQQ
TQVKLSDGMPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPPYFRGSYTFGEVH
TNSQKVSSASQGEAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIH
CLGGVGRTGTMAAALVLKDNPHSNLEQVRADFRDSRNNRMLEDASQFVQLKAMQAQLLMTTAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sptP NP_461799.1 protein tyrosine phosphatase/GTPase activating protein Virulence SPI-1 Protein 0.0 100
sptP YP_217797.1 protein tyrosine phosphate Not tested SPI-1 Protein 0.0 99
stpA NP_457272.1 tyrosine phosphatase (associated with virulence) Virulence SPI-1 Protein 0.0 95
stpA NP_806481.1 tyrosine phosphatase Virulence SPI-1 Protein 0.0 95

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CFSAN001921_02685 YP_008253945.1 pathogenicity island 1 effector protein StpP VFG0540 Protein 0.0 100